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THROMBOSIS OF THE CAVERNOUS SINUS WITH HEMOLYTIC STREPTOCOCCIC BACTEREMIA: TREATMENT BY INTRAVENOUS INJECTION OF SULFADIAZINE AND PENICILLIN, WITH RECOVERY

THROMBOSIS OF THE CAVERNOUS SINUS WITH HEMOLYTIC STREPTOCOCCIC BACTEREMIA: TREATMENT BY... Abstract Prior to the era of chemotherapy, true cases of thrombosis of the cavernous sinuses were invariably fatal. None that I know was ever reported with cure. Medical treatment was of no avail. Surgical procedures, such as ligation of the facial vein, met with similar results. Since the introduction of sulfonamide compounds, however, a number of cases of thrombosis of the cavernous sinus have been reported with cure.1 Before presenting my case I shall review briefly the etiology and trace the course of the thrombus from the source of infection to the cavernous sinus. Infection originates from anterior, intranasal, posterior and inferior foci. In this case the port of entrance was anterior: a furuncle on the bridge of the nose. The septic thrombus spread to the angular, to the supraorbital, to the supratrochlear and to the ophthalmic vein, emptying into the cavernous sinus. There it extended to the opposite side, affecting References 1. Seydell, E. M.: Recovery from Thrombosis of the Cavernous Sinus , Arch. Otolaryng. 30:429 ( (Sept.) ) 1939.Crossref 2. Morrison, L. F., and Schindler, M.: Cavernous Sinus Thrombosis , Arch. Otolaryng. 31:948 ( (June) ) 1940.Crossref 3. Skemp, H. L.; Afremow, M. L., and Rhoads, P. S.: Cavernous Sinus Thrombosis , Arch. Otolaryng. 34:1025 ( (Nov.) ) 1941.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

THROMBOSIS OF THE CAVERNOUS SINUS WITH HEMOLYTIC STREPTOCOCCIC BACTEREMIA: TREATMENT BY INTRAVENOUS INJECTION OF SULFADIAZINE AND PENICILLIN, WITH RECOVERY

Archives of Otolaryngology , Volume 40 (1) – Jul 1, 1944

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Publisher
American Medical Association
Copyright
Copyright © 1944 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1944.00680020045004
Publisher site
See Article on Publisher Site

Abstract

Abstract Prior to the era of chemotherapy, true cases of thrombosis of the cavernous sinuses were invariably fatal. None that I know was ever reported with cure. Medical treatment was of no avail. Surgical procedures, such as ligation of the facial vein, met with similar results. Since the introduction of sulfonamide compounds, however, a number of cases of thrombosis of the cavernous sinus have been reported with cure.1 Before presenting my case I shall review briefly the etiology and trace the course of the thrombus from the source of infection to the cavernous sinus. Infection originates from anterior, intranasal, posterior and inferior foci. In this case the port of entrance was anterior: a furuncle on the bridge of the nose. The septic thrombus spread to the angular, to the supraorbital, to the supratrochlear and to the ophthalmic vein, emptying into the cavernous sinus. There it extended to the opposite side, affecting References 1. Seydell, E. M.: Recovery from Thrombosis of the Cavernous Sinus , Arch. Otolaryng. 30:429 ( (Sept.) ) 1939.Crossref 2. Morrison, L. F., and Schindler, M.: Cavernous Sinus Thrombosis , Arch. Otolaryng. 31:948 ( (June) ) 1940.Crossref 3. Skemp, H. L.; Afremow, M. L., and Rhoads, P. S.: Cavernous Sinus Thrombosis , Arch. Otolaryng. 34:1025 ( (Nov.) ) 1941.Crossref

Journal

Archives of OtolaryngologyAmerican Medical Association

Published: Jul 1, 1944

References