This Week in JAMA
Abstract
Lansoprazole for Poorly Controlled Asthma Asymptomatic gastroesophageal reflux (GER) is prevalent in children with asthma, and untreated GER has been postulated as a cause of poor asthma control. Investigators from 19 American Lung Association Asthma Clinical Research Center sites randomly assigned 306 children with poor asthma control despite inhaled corticosteroid treatment and without symptomatic GER to receive either the proton pump inhibitor lansoprazole or placebo for 24 weeks. The...