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The Utility of the Dexamethasone Suppression Test

The Utility of the Dexamethasone Suppression Test Abstract To the Editor.— IN the December 1985 issue of the Archives, Arana and colleagues1 extensively review the use of the dexamethasone suppression test (DST) in various clinical states and comment on the "ability of the DST to differentiate depression from selected, clinically pertinent conditions." The authors summarize the DST results in major depressive disorder vs the selected comparison groups in Table 5 of their article. Chronic pain is one of the selected comparison groups, and the authors quote from two references2,3 on chronic pain and major depressive disorder and one reference on chronic pain4 to calculate the sensitivity and specificity of the DST. It should be noted that two of the references2,3 refer to a study of the DST but contain no mention of the DST in patients with chronic pain. The article by Blumer et al5 does indeed report on the results of the References 1. Arana GW, Baldessarini RJ, Ornsteen M: The dexamethasone suppression test for diagnosis and prognosis in psychiatry . Arch Gen Psychiatry 1985;42:1193-1204.Crossref 2. Vital-Herne J, Halbreich U, Zander KJ, Asnis G, Goldstein S, Gasparini F: Clinical correlates of the afternoon cortisol test in depression, abstract 109. Program and abstracts of the Society for Biological Psychiatry Scientific Proceedings, Los Angeles, May 2-6, 1984, p 151. 3. Dewan MJ, Pandurangi AK, Boucher ML, Levy BF, Major LF: Abnormal dexamethasone suppression test results in chronic schizophrenic patients . Am J Psychiatry 1982;139:1501-1503. 4. France RD, Krishnan KRR, Houpt JL, Maltbie AA: Differentiation of depression from chronic pain with the dexamethasone suppression test and DSM-III . Am J Psychiatry 1984;141:1577-1579. 5. Blumer D, Zorick F, Heilbronn M, Roth T: Biological markers for depression in chronic pain . J Nerv Ment Dis 1982;170:425-428.Crossref 6. Atkinson J, Kremer E, Risch S, Janowsky D: Neuroendocrine markers of affective disorder in chronic pain . Pain Suppl 1984;2:209.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of General Psychiatry American Medical Association

The Utility of the Dexamethasone Suppression Test

The Utility of the Dexamethasone Suppression Test

Abstract

Abstract To the Editor.— IN the December 1985 issue of the Archives, Arana and colleagues1 extensively review the use of the dexamethasone suppression test (DST) in various clinical states and comment on the "ability of the DST to differentiate depression from selected, clinically pertinent conditions." The authors summarize the DST results in major depressive disorder vs the selected comparison groups in Table 5 of their article. Chronic pain is one of the selected comparison...
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Publisher
American Medical Association
Copyright
Copyright © 1987 American Medical Association. All Rights Reserved.
ISSN
0003-990X
eISSN
1598-3636
DOI
10.1001/archpsyc.1987.01800130107017
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.— IN the December 1985 issue of the Archives, Arana and colleagues1 extensively review the use of the dexamethasone suppression test (DST) in various clinical states and comment on the "ability of the DST to differentiate depression from selected, clinically pertinent conditions." The authors summarize the DST results in major depressive disorder vs the selected comparison groups in Table 5 of their article. Chronic pain is one of the selected comparison groups, and the authors quote from two references2,3 on chronic pain and major depressive disorder and one reference on chronic pain4 to calculate the sensitivity and specificity of the DST. It should be noted that two of the references2,3 refer to a study of the DST but contain no mention of the DST in patients with chronic pain. The article by Blumer et al5 does indeed report on the results of the References 1. Arana GW, Baldessarini RJ, Ornsteen M: The dexamethasone suppression test for diagnosis and prognosis in psychiatry . Arch Gen Psychiatry 1985;42:1193-1204.Crossref 2. Vital-Herne J, Halbreich U, Zander KJ, Asnis G, Goldstein S, Gasparini F: Clinical correlates of the afternoon cortisol test in depression, abstract 109. Program and abstracts of the Society for Biological Psychiatry Scientific Proceedings, Los Angeles, May 2-6, 1984, p 151. 3. Dewan MJ, Pandurangi AK, Boucher ML, Levy BF, Major LF: Abnormal dexamethasone suppression test results in chronic schizophrenic patients . Am J Psychiatry 1982;139:1501-1503. 4. France RD, Krishnan KRR, Houpt JL, Maltbie AA: Differentiation of depression from chronic pain with the dexamethasone suppression test and DSM-III . Am J Psychiatry 1984;141:1577-1579. 5. Blumer D, Zorick F, Heilbronn M, Roth T: Biological markers for depression in chronic pain . J Nerv Ment Dis 1982;170:425-428.Crossref 6. Atkinson J, Kremer E, Risch S, Janowsky D: Neuroendocrine markers of affective disorder in chronic pain . Pain Suppl 1984;2:209.Crossref

Journal

Archives of General PsychiatryAmerican Medical Association

Published: Jan 1, 1987

References