Abstract The introduction of sulfanilamide to the medical profession in 1936 has brought about many changes in therapy in practically every field of medicine. Probably there is no field or specialty in which its value has not been tested clinically as well as experimentally in the laboratory. Nor is there any field in which its value has not been proved as a decided aid to therapy of conditions for which there has been heretofore no valuable remedy. With the introduction of any new effective drug there is a tendency to extend its use more or less promiscuously. Such spectacular results were obtained with sulfanilamide in many cases of streptococcic infections that it was soon used for all recalcitrant ailments. Its improper use was partly due to the popular belief at the outset that the drug was harmless and did not cause any untoward manifestations. This practice precipitated a large number of References 1. Domagk, G.: Deutsche med. Wchnschr. 61:250, 1935.Crossref 2. 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B.: Recurrent Erysipelas Successfully Treated with Sulfanilamide , Arch. Dermat. & Syph. 40:498 ( (Sept.) ) 1939. 64. Sandler, I. L.: Sulfanilamide Treatment of Syphilitic Interstitial Keratitis , Arch. Dermat. & Syph. 39:528 ( (March) ) 1939. 65. Shaffer, L. W., and Arnold, E.: Lymphogranuloma Venereum; Especially Its Treatment with Sulfanilamide , Arch. Dermat. & Syph. 38:705 ( (Nov.) ) 1938. 66. Montel, L. R., and Nguyen-van-Tho: Bull. Soc. franç. de dermat. et syph. 45:652, 1938. 67. Warren, L. H.: Lymphogranuloma Venereum , Arch. Dermat. & Syph. 38:262 ( (Aug.) ) 1938. 68. Greenbaum, S. S., in discussion on Warren.67 69. Kornblith, B. A.; Jacoby, A., and Wishengrad, M.: Treatment of Chancroid with Sulfanilamide , J. A. M. A. 111:523 ( (Aug. 6) ) 1938. 70. Fox, H.: Chancroidal Ulcer of Long Standing Cured by Sulfanilamide , Arch. Dermat. & Syph. 38:660 ( (Oct.) ) 1938. 71. Lepinay: Bull. Soc. franç. de dermat. et syph. 45:1728, 1938. 72. Schwartz, W. 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Archives of Dermatology and Syphilology – American Medical Association
Published: Jul 1, 1940
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