Abstract The U wave has in the past received but little attention in clinical electrocardiography, as its significance was not clear. However, during the last few years methods have been developed which allow electrocardiographic leads to be taken directly from the inside of the heart muscle cell and thus make it possible to obtain new information concerning the significance of the U wave and the electrochemical processes responsible for it. On the other hand, an increasing number of reports is appearing in which changes of the U wave are found to be the chief clue leading toward the correct clinical diagnosis. Furthermore, the study of the U waves may furnish important information concerning the genesis of ventricular arrhythmias. I first became interested in the U wave and the after-potentials responsible for it almost exactly 20 years ago, when, as a student, I watched the experiments of Drs. C. J. Rothberger and References 1. References 1 and 12. 2. References 1 and 2. 3. References 1 and 10. 4. References 7-9 and 12. 5. References 7-9. 6. References 5 and 6. 7. References 3 and 4. 8. References 9, 12, and 18. 9. References 3 and 6. 10. References 3 and 5. 11. References 3 and 4. 12. References 3, 4, 7, and 11. 13. References 4 and 5. 14. References 2, 15, and 17. 15. References 15 and 17. 16. References 2 and 15-17. 17. E. Lepeschkin (with comments by E. Bozler, D. Littman, J. H. Palmer, C. Papp, T. Sjöstrand, and B. Surawicz): Definition and Measurement of the U Wave. 18. Max Holzmann: The Various Types of Fusion between the T and U Wave. 19. Marcel Segers (with comments by S. Bellet, E. Bozler, E. Lepeschkin, and L. Nahum): The After-Potentials of the Frog's Heart. 20. Emil Bozler (with comments by E. Lepeschkin, L. Nahum, F. Sichel, and B. Surawicz): Non-Propagated Action Potentials of Cardiac Muscle. 21. E. Lepeschkin (with comments by H. H. Hecht, M. Kleinfeld, M. Trautwein, and S. Weidmann): The Intracellular After-Potentials of the Heart and Their Interpretation. 22. Lepeschkin (with comments by E. Bozler and L. Nahum): The Genesis of the U Wave. 23. L. H. Nahum and S. Nuland (with comments by E. Lepeschkin): Instantaneous Equipotential Distribution on the Body Surface During Moments in the U Wave in Normal Subjects and in Patients with Cardiac Pathology. 24. Jan Nyboer (with comments by E. Lepeschkin): The U Wave in Esophageal Electrocardiograms. 25. E. Lepeschkin: The Form of the Normal U Wave. 26. E. Lepeschkin and B. Surawicz: The Duration of the U Wave in Relation to the Heart Rate and the Mechanical Events of the Cardiac Cycle. 27. M. B. Rosenbaum and E. Lepeschkin: The Coupling Interval of Ventricular Extrasystoles in Relation to the U Wave and the Supernormal Phase of Excitability. 28. Borys Surawicz, Robert L. Kemp, and Samuel Bellet: The Polarity and Amplitude of the U Wave of the Electrocardiogram in Relation to that of the T Wave. 29. Robert L. Kemp, Borys Surawicz, John C. Bettinger, Harry Gottlieb, and Samuel Bellet: The Prognostic Significance of Negative U Waves of the Electrocardiogram in Hypertension. 30. Joseph Lambert: Clinical Study of the Abnormalities of the Terminal Complex TU-U of the Electrocardiogram. 31. Cornelio Papp (with comments by R. L. Kemp, E. Lepeschkin, M. B. Rosenbaum, and B. Surawicz): The U Wave in Coronary Disease. 32. J. H. Palmer (with comments by M. Holzmann, R. L. Kemp, E. Lepeschkin, L. Nahum, M. B. Rosenbaum, and B. Surawicz): The Clinical Significance of Inverted U Waves. 33. E. Lepeschkin and Borys Surawicz: The U Wave in Positive and Negative Exercise Tests. 34. Stephen R. Elek: Some Positive Knowledge Regarding the U Wave.
A.M.A. Archives of Internal Medicine – American Medical Association
Published: Nov 1, 1955