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THE TREATMENT OF PERNICIOUS ANEMIA WITH DESICCATED HOG'S STOMACH: PROF. I. SNAPPER, M.D. AND J. D. G. DU PREEZ, M.D. AMSTERDAM, HOLLAND

THE TREATMENT OF PERNICIOUS ANEMIA WITH DESICCATED HOG'S STOMACH: PROF. I. SNAPPER, M.D. AND J.... Abstract On the continent of Europe this subject has been investigated chiefly by Faber, Ewald, Zadek, Weinberg and others, Faber expressing as his opinion that achylia gastrica is generally preceded by a chronic gastritis. In England Hurst was the chief exponent; he also showed by means of the fractional test meal that the absence of free hydrochloric acid in pernicious anemia invariably persists throughout the whole period of digestion, whereas in other conditions, such as cancer of the stomach, it is not uncommon to find a small quantity of free acid in one or more of the fractions. The significance of this achylia was pointed out by Castle,1 who in a series of experiments with normal gastric juice and beef muscle, administered in different ways to patients with pernicious anemia, endeavored to establish an etiologic relationship between achylia gastrica and pernicious anemia. This constant achylia and the facts concerning the familial References 1. Castle: Brit. M. J. 1:1120, 1929 2. Am. J. M. Sc. 178:748, 1929.Crossref 3. Castle and Townsend: Am. J. M. Sc. 178:764, 1929.Crossref 4. Sharp, E. H.: Antianemic Factor in Desiccated Stomach , J. A. M. A. 93:749 ( (Sept. 7) ) 1929.Crossref 5. Sturgis, C. S., and Isaacs, R.: Desiccated Stomach in the Treatment of Pernicious Anemia , J. A. M. A. 93:747 ( (Sept. 7) ) 1929.Crossref 6. Conner, H. M.: Treatment of Pernicious Anemia with Swine Stomach , J. A. M. A. 94:388 ( (Feb. 8) ) 1930.Crossref 7. Minot and Medearis: J. Clin. Investigation 3:541 ( (Feb. 20) ) 1927.Crossref 8. Snapper, I., and du Preez, J. D. G.: Nederl. tijdschr. v. geneesk. 74:745 ( (Feb. 15) ) 1930. 9. Wilkinson: Brit. M. J. 1:236 ( (Feb. 8) ) 1930.Crossref 10. Renshaw: Brit. M. J. 1:334 ( (Feb. 22) ) 1930.Crossref 11. Hitzenberger: Wien. klin. Wchnschr. 43:367, 1930. 12. Rosenow: Klin. Wchnschr. 9:652 ( (April 5) ) 1930.Crossref 13. Meulengracht and Hecht-Johansen: Klin. Wchnschr. 9:1162 ( (June 21) ) 1930.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

THE TREATMENT OF PERNICIOUS ANEMIA WITH DESICCATED HOG'S STOMACH: PROF. I. SNAPPER, M.D. AND J. D. G. DU PREEZ, M.D. AMSTERDAM, HOLLAND

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Publisher
American Medical Association
Copyright
Copyright © 1931 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1931.00140230098007
Publisher site
See Article on Publisher Site

Abstract

Abstract On the continent of Europe this subject has been investigated chiefly by Faber, Ewald, Zadek, Weinberg and others, Faber expressing as his opinion that achylia gastrica is generally preceded by a chronic gastritis. In England Hurst was the chief exponent; he also showed by means of the fractional test meal that the absence of free hydrochloric acid in pernicious anemia invariably persists throughout the whole period of digestion, whereas in other conditions, such as cancer of the stomach, it is not uncommon to find a small quantity of free acid in one or more of the fractions. The significance of this achylia was pointed out by Castle,1 who in a series of experiments with normal gastric juice and beef muscle, administered in different ways to patients with pernicious anemia, endeavored to establish an etiologic relationship between achylia gastrica and pernicious anemia. This constant achylia and the facts concerning the familial References 1. Castle: Brit. M. J. 1:1120, 1929 2. Am. J. M. Sc. 178:748, 1929.Crossref 3. Castle and Townsend: Am. J. M. Sc. 178:764, 1929.Crossref 4. Sharp, E. H.: Antianemic Factor in Desiccated Stomach , J. A. M. A. 93:749 ( (Sept. 7) ) 1929.Crossref 5. Sturgis, C. S., and Isaacs, R.: Desiccated Stomach in the Treatment of Pernicious Anemia , J. A. M. A. 93:747 ( (Sept. 7) ) 1929.Crossref 6. Conner, H. M.: Treatment of Pernicious Anemia with Swine Stomach , J. A. M. A. 94:388 ( (Feb. 8) ) 1930.Crossref 7. Minot and Medearis: J. Clin. Investigation 3:541 ( (Feb. 20) ) 1927.Crossref 8. Snapper, I., and du Preez, J. D. G.: Nederl. tijdschr. v. geneesk. 74:745 ( (Feb. 15) ) 1930. 9. Wilkinson: Brit. M. J. 1:236 ( (Feb. 8) ) 1930.Crossref 10. Renshaw: Brit. M. J. 1:334 ( (Feb. 22) ) 1930.Crossref 11. Hitzenberger: Wien. klin. Wchnschr. 43:367, 1930. 12. Rosenow: Klin. Wchnschr. 9:652 ( (April 5) ) 1930.Crossref 13. Meulengracht and Hecht-Johansen: Klin. Wchnschr. 9:1162 ( (June 21) ) 1930.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: May 1, 1931

References