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THE TOXIN OF THE GONOCOCCUS.

THE TOXIN OF THE GONOCOCCUS. In view of the prevalence of gonorrhea and of the obstinacy of this disease to treatment, all new facts in regard to the biology of its microbe must be of interest. De Christmas and others have demonstrated that the gonococcus elaborates toxic substances capable of producing suppuration and fever in animals, and a purulent urethritis in man. The latter is characterized by abundant pus formation and heals spontaneously in a few days. The toxic substance or substances are found partly in the bodies of the cocci, partly dissolved in the liquid of the culture medium. De Christmas states that animals may be immunized against the toxin by the inoculation of successively increasing doses thereof. These observations have been questioned by other writers who found the gonococcus more or less feeble in its power to produce toxin. Evidently the composition of the medium upon which it is grown plays an important http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

THE TOXIN OF THE GONOCOCCUS.

JAMA , Volume XXXV (1) – Jul 7, 1900

THE TOXIN OF THE GONOCOCCUS.

Abstract


In view of the prevalence of gonorrhea and of the obstinacy of this disease to treatment, all new facts in regard to the biology of its microbe must be of interest. De Christmas and others have demonstrated that the gonococcus elaborates toxic substances capable of producing suppuration and fever in animals, and a purulent urethritis in man. The latter is characterized by abundant pus formation and heals spontaneously in a few days. The toxic substance or substances are found partly...
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Publisher
American Medical Association
Copyright
Copyright © 1900 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1900.02460270044012
Publisher site
See Article on Publisher Site

Abstract

In view of the prevalence of gonorrhea and of the obstinacy of this disease to treatment, all new facts in regard to the biology of its microbe must be of interest. De Christmas and others have demonstrated that the gonococcus elaborates toxic substances capable of producing suppuration and fever in animals, and a purulent urethritis in man. The latter is characterized by abundant pus formation and heals spontaneously in a few days. The toxic substance or substances are found partly in the bodies of the cocci, partly dissolved in the liquid of the culture medium. De Christmas states that animals may be immunized against the toxin by the inoculation of successively increasing doses thereof. These observations have been questioned by other writers who found the gonococcus more or less feeble in its power to produce toxin. Evidently the composition of the medium upon which it is grown plays an important

Journal

JAMAAmerican Medical Association

Published: Jul 7, 1900

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