Abstract The goal of therapy in the burn patient is to secure coverage of the injured area with the body's own tissues with or without operative assistance. Apart from the problems of initial resuscitation, burn wound sepsis constitutes the greatest threat to recovery. Studies of burn wound sepsis and the vascular destruction causing death of tissue have shown that topically applied antibacterial agents are more effective than those systemically administered.1,2 The agent must, however, be applied often enough and in such concentrations as to make it effective. Topical therapy does not include the application of a medically impregnated gauze which is not changed for several days. Topical agents in water-soluble bases can be used without any dressings or bandages. Daily hydrotherapy removes topical agent and dead tissue and a progressive debridement is achieved. During the four year period (1964-1967), 282 children, ranging in age from 1 month to 15 years, References 1. Teplitz, C., et al: Pseudomonas Burn Wound Sepsis: I. Pathogenesis of Experimental Pseudomonas Burn Wound Sepsis , J Surg Res 4:200-216 ( (May) ) 1964.Crossref 2. Order, S.E., et al: Vascular Destructive Effects of Thermal Injury and Its Relationship to Burn Wound Sepsis , J Trauma 5:62-71 ( (Jan) ) 1965.Crossref 3. Moncrief, J.A., et al: The Use of a Topical Sulfonamide in the Control of Burn Wound Sepsis , J Trauma 6:407-419 ( (May) ) 1966.Crossref 4. Moncrief, J.A.: The Status of Topical Antibacterial Therapy in the Treatment of Burns , Surgery 63:862-867 ( (May) ) 1968. 5. Larson, cited by Rittenbury, M.S., and Yarbrough, D.R., III: Special Report: the Eighth National Burn Seminar , J Surg Res 8:142-150 ( (March) ) 1968.Crossref 6. Boles, E.T., Jr., and Terry, J.L.: Practical Aspects of the Management of Severely Burned Children , Amer J Surg 101:668-676 ( (May) ) 1961.Crossref 7. Markley, L., et al: The Influence of Fluid Therapy Upon Water and Electrolyte Equilibria and Upon the Circulation During the Shock Period in Burned Patients , Surgery 49:161-178 ( (Feb) ) 1961. 8. Feller, I., and DeWeese, M.S.: A Reappraisal of Fluid Therapy in the Burned Patient , JAMA 181:361-365 ( (Aug 4) ) 1962.Crossref 9. Shook, CD.; MacMillan, B.G.; and Altemeier, W.A.: Pulmonary Complications of the Burn Patient , Arch Surg 97:215-224 ( (Aug) ) 1968.Crossref 10. Foley, F.D.; Moncrief, J.A.; and Mason, A.D., Jr.: Pathology of the Lung in Fatally Burned Patients , Ann Surg 167:251-264 ( (Feb) ) 1968.Crossref 11. Stone, H.H., et al: Respiratory Burns: A Correlation of Clinical and Laboratory Results , Ann Surg 165:157-168 ( (Feb) ) 1967.Crossref 12. O'Neill, J.A., Jr., et al: Studies Related to the Pathogenesis of Curling's Ulcer , J Trauma 7:275-287 ( (March) ) 1967.Crossref 13. Haynes, B.W., Jr., and Bright, R.: Burn Coma: A Syndrome Associated With Severe Burn Wound Infection , J Trauma 7:464-475 ( (May) ) 1967.Crossref 14. Evans, E.B.: Orthopaedic Measures in the Treatment of Severe Burns , J Bone Joint Surg 48A:643-669 ( (June) ) 1966.
Archives of Surgery – American Medical Association
Published: Apr 1, 1969