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The Timing of Reoperation for Incidental Gallbladder Cancer

The Timing of Reoperation for Incidental Gallbladder Cancer Optimal Time for Re-resection for Incidental Gallbladder Cancer Original Investigation Research analysis of surgical findings and survival. J Surg Oncol. 15. Isambert M, Leux C, Métairie S, Paineau J. why and which reoperation? J Visc Surg. 2011;148 2010;102(6):620-625. Incidentally-discovered gallbladder cancer: when, (2):e77-e84. Invited Commentary Sooner or Later? Vatche G. Agopian, MD; Jonathan R. Hiatt, MD Incidental gallbladder cancer is reported in approximately They suggest that early reoperation (less than 4 weeks) may not 0.7% of patients undergoing a cholecystectomy. While the allow for an adequate assessment of advanced subclinical dis- need for surgical re-resection and staging portal lymphad- ease, while late reoperation (more than 8 weeks) may allow for enectomy in the absence of metastatic disease is not debated, dissemination of subclinical disease that remains undetected, the optimal timing of reoperation is unknown. explaining the inferior outcomes in these 2 groups. While it is Ethun and colleagues investigate this question using ret- undeniable that time allows for manifestation of subclinical dis- rospective data from the multi-institution US Extrahepatic Bili- ease, it is difficult to reconcile the authors’ contention that a few ary Malignancy Consortium database. They suggest that re- extra weeks of early observation allowed the identification of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Surgery American Medical Association

The Timing of Reoperation for Incidental Gallbladder Cancer

Agopian, Vatche G.; Hiatt, Jonathan R.
JAMA Surgery , Volume 152 (2) – Feb 26, 2017
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The Timing of Reoperation for Incidental Gallbladder Cancer

Abstract

Optimal Time for Re-resection for Incidental Gallbladder Cancer Original Investigation Research analysis of surgical findings and survival. J Surg Oncol. 15. Isambert M, Leux C, Métairie S, Paineau J. why and which reoperation? J Visc Surg. 2011;148 2010;102(6):620-625. Incidentally-discovered gallbladder cancer: when, (2):e77-e84. Invited Commentary Sooner or Later? Vatche G. Agopian, MD; Jonathan R. Hiatt, MD Incidental gallbladder cancer is reported in approximately They suggest...
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Publisher
American Medical Association
Copyright
Copyright 2016 American Medical Association. All Rights Reserved.
ISSN
2168-6254
eISSN
2168-6262
DOI
10.1001/jamasurg.2016.3643
pmid
27784061
Publisher site
See Article on Publisher Site

Abstract

Optimal Time for Re-resection for Incidental Gallbladder Cancer Original Investigation Research analysis of surgical findings and survival. J Surg Oncol. 15. Isambert M, Leux C, Métairie S, Paineau J. why and which reoperation? J Visc Surg. 2011;148 2010;102(6):620-625. Incidentally-discovered gallbladder cancer: when, (2):e77-e84. Invited Commentary Sooner or Later? Vatche G. Agopian, MD; Jonathan R. Hiatt, MD Incidental gallbladder cancer is reported in approximately They suggest that early reoperation (less than 4 weeks) may not 0.7% of patients undergoing a cholecystectomy. While the allow for an adequate assessment of advanced subclinical dis- need for surgical re-resection and staging portal lymphad- ease, while late reoperation (more than 8 weeks) may allow for enectomy in the absence of metastatic disease is not debated, dissemination of subclinical disease that remains undetected, the optimal timing of reoperation is unknown. explaining the inferior outcomes in these 2 groups. While it is Ethun and colleagues investigate this question using ret- undeniable that time allows for manifestation of subclinical dis- rospective data from the multi-institution US Extrahepatic Bili- ease, it is difficult to reconcile the authors’ contention that a few ary Malignancy Consortium database. They suggest that re- extra weeks of early observation allowed the identification of

Journal

JAMA Surgery – American Medical Association

Published: Feb 26, 2017

References

  • Clinical characteristics of incidental or unsuspected gallbladder cancers diagnosed during or after cholecystectomy: a systematic review and meta-analysis
    Choi, KS; Choi, SB; Park, P; Kim, WB; Choi, SY
  • Gallbladder cancer: expert consensus statement
    Aloia, TA; Járufe, N; Javle, M
  • Association of optimal time interval to re-resection for incidental gallbladder cancer with overall survival: a multi-institutional analysis from the US Extrahepatic Biliary Malignancy Consortium [published online October 26, 2016]
    Ethun, CG; Postlewait, LM; Le, N

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