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The Summating Potential and Meniere's Disease: I. Summating Potential Amplitude in Meniere and Non-Meniere Ears

The Summating Potential and Meniere's Disease: I. Summating Potential Amplitude in Meniere and... Abstract • We investigated the relationship between Meniere's disease and the abnormally enlarged summating potential (SP) in a series of patients and normal subjects. Cochlear and auditory nerve responses to rectangular-pulse clicks, delivered at a rate of 8/s and an intensity of 115 dB peak-equivalent sound pressure level, were recorded from ear canal skin. We performed a parabolic regression for SP amplitudes as a function of auditory nerve action potential (AP) amplitudes in normal ears and obtained the 95% confidence interval (±2 SD) for normal scatter around the fitted curve. Sixty-eight percent of SP amplitudes from ears with Meniere's disease exceeded the upper normal confidence limit. In contrast, only 7% of the cochlear ears and none of the retrocochlear ears had SP amplitudes above this normal upper limit. Cochlear microphonic potentials and APs from the ears with Meniere's disease also tended to be larger than normal, but this tendency was not strong enough to be of diagnostic use. (Arch Otolaryngol 1981;107:199-208) References 1. Eggermont JJ: Summating potentials in electrocochleography: Relation to hearing disorders , in Ruben RJ, Elberling C, Salomon G (eds): Electrocochleography . Baltimore, University Park Press, 1976, pp 67-87. 2. Yoshie N: Electrocochleographic classification of sensorineural defects: Pathological pattern of the cochlear nerve compound action potential in man , in Ruben RJ, Elberling C, Salomon G (eds): Electrocochleography . Baltimore, University Park Press, 1976, pp 353-386. 3. Gibson WPR, Moffat DA, Ramsden RT: Clinical electrocochleography in the diagnosis and management of Meniere's disorder . Audiology 1977;16:389-401.Crossref 4. Eggermont JJ: Summating potentials in Meniere's disease . Arch Otolaryngol 1979;222:63-75. 5. Ramsden RT, Moffat DA, Gibson WPR: Transtympanic electrocochleography in patients with syphilis and hearing loss . Ann Otol Rhinol Laryngol 1977;86:827-834. 6. Coats AC: On electrocochleographic electrode design . J Acoust Soc Am 1974;56:708-711.Crossref 7. Coats AC, Martin JL, Kidder HR: Normal short-latency electrophysiological filtered click responses recorded from vertex and external auditory meatus . J Acoust Soc Am 1979;65:747-758.Crossref 8. Coats AC, Kidder HR: Effect of earspeaker coupling on auditory action potential and brainstem responses . Arch Otolaryngol 1980;106:339-344.Crossref 9. Eggermont JJ, Odenthal DW: The summating potential in man: Identification and properties . Acta Otolaryngol 1974;316:52-53. 10. Hallpike CS, Cairns H: Observations on the pathology of Meniere's syndrome . J Laryngol Otol 1938;53:625-654.Crossref 11. Hallpike CS, Wright AJ: On the histological changes in temporal bones of a case of Meniere's disease . J Laryngol Otol 1940;55:59-66. 12. Brunner H: Meniere's disease . J Laryngol Otol 1948;62:627-638.Crossref 13. Lindsay JR: Hydrops of the labyrinth . Arch Otolaryngol 1960;71:500-512.Crossref 14. Kristensen HK: Histopathology in Meniere's disease . Acta Otolaryngol 1961;53:237-248.Crossref 15. Schuknecht HF, Benitez JT, Beekhuis J: Further observations on the pathology of Meniere's disease . Ann Otol Rhinol Laryngol 1962;71:1039-1053. 16. Schuknecht HF: Meniere's disease: A correlation of symptomatology and pathology . Laryngoscope 1963;73:651-665.Crossref 17. Altmann F, Kornfeld M: Histological studies of Meniere's disease . Ann Otol Rhinol Laryngol 1965;74:915-944. 18. Schuknecht HF: Pathology of Meniere's disease . Otolaryngol Clin North Am 1968;1:331-337. 19. Schuknecht HF: Pathology of the Ear . Cambridge, Mass, Harvard University Press, 1974. 20. Alford BR: Meniere's disease: Criteria for diagnosis and evaluation of therapy for reporting . Trans Am Acad Ophthalmol Otolaryngol 1972;76:1462-1464. 21. Croxton FE, Cowden DJ: Applied General Statistics . Englewood Cliffs, NJ, Prentice-Hall, 1955. 22. Aran J-M: Clinical measures of VIIIth nerve function . Adv Otorhinolaryngol 1973; 20:374-394. 23. Coats AC, Martin JL: Human auditory nerve action potentials and brain stem evoked responses: Effects of audiogram shape and lesion location . Arch Otolaryngol 1977;103:605-622.Crossref 24. Dallos P, Schoeny ZG, Cheatman MA: Cochlear summating potentials . Acta Otolaryngol 1972;302:1-43. 25. Aran J-M, de Sauvage RC: Clinical value of cochlear microphonic recordings , in Ruben RJ, Elberling C, Salomon G (eds): Electrocochleography . Baltimore, University Park Press, 1976, pp 55-65. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

The Summating Potential and Meniere's Disease: I. Summating Potential Amplitude in Meniere and Non-Meniere Ears

Archives of Otolaryngology , Volume 107 (4) – Apr 1, 1981

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Publisher
American Medical Association
Copyright
Copyright © 1981 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1981.00790400001001
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Abstract

Abstract • We investigated the relationship between Meniere's disease and the abnormally enlarged summating potential (SP) in a series of patients and normal subjects. Cochlear and auditory nerve responses to rectangular-pulse clicks, delivered at a rate of 8/s and an intensity of 115 dB peak-equivalent sound pressure level, were recorded from ear canal skin. We performed a parabolic regression for SP amplitudes as a function of auditory nerve action potential (AP) amplitudes in normal ears and obtained the 95% confidence interval (±2 SD) for normal scatter around the fitted curve. Sixty-eight percent of SP amplitudes from ears with Meniere's disease exceeded the upper normal confidence limit. In contrast, only 7% of the cochlear ears and none of the retrocochlear ears had SP amplitudes above this normal upper limit. Cochlear microphonic potentials and APs from the ears with Meniere's disease also tended to be larger than normal, but this tendency was not strong enough to be of diagnostic use. (Arch Otolaryngol 1981;107:199-208) References 1. Eggermont JJ: Summating potentials in electrocochleography: Relation to hearing disorders , in Ruben RJ, Elberling C, Salomon G (eds): Electrocochleography . Baltimore, University Park Press, 1976, pp 67-87. 2. Yoshie N: Electrocochleographic classification of sensorineural defects: Pathological pattern of the cochlear nerve compound action potential in man , in Ruben RJ, Elberling C, Salomon G (eds): Electrocochleography . Baltimore, University Park Press, 1976, pp 353-386. 3. Gibson WPR, Moffat DA, Ramsden RT: Clinical electrocochleography in the diagnosis and management of Meniere's disorder . Audiology 1977;16:389-401.Crossref 4. Eggermont JJ: Summating potentials in Meniere's disease . Arch Otolaryngol 1979;222:63-75. 5. Ramsden RT, Moffat DA, Gibson WPR: Transtympanic electrocochleography in patients with syphilis and hearing loss . Ann Otol Rhinol Laryngol 1977;86:827-834. 6. Coats AC: On electrocochleographic electrode design . J Acoust Soc Am 1974;56:708-711.Crossref 7. Coats AC, Martin JL, Kidder HR: Normal short-latency electrophysiological filtered click responses recorded from vertex and external auditory meatus . J Acoust Soc Am 1979;65:747-758.Crossref 8. Coats AC, Kidder HR: Effect of earspeaker coupling on auditory action potential and brainstem responses . Arch Otolaryngol 1980;106:339-344.Crossref 9. Eggermont JJ, Odenthal DW: The summating potential in man: Identification and properties . Acta Otolaryngol 1974;316:52-53. 10. Hallpike CS, Cairns H: Observations on the pathology of Meniere's syndrome . J Laryngol Otol 1938;53:625-654.Crossref 11. Hallpike CS, Wright AJ: On the histological changes in temporal bones of a case of Meniere's disease . J Laryngol Otol 1940;55:59-66. 12. Brunner H: Meniere's disease . J Laryngol Otol 1948;62:627-638.Crossref 13. Lindsay JR: Hydrops of the labyrinth . Arch Otolaryngol 1960;71:500-512.Crossref 14. Kristensen HK: Histopathology in Meniere's disease . Acta Otolaryngol 1961;53:237-248.Crossref 15. Schuknecht HF, Benitez JT, Beekhuis J: Further observations on the pathology of Meniere's disease . Ann Otol Rhinol Laryngol 1962;71:1039-1053. 16. Schuknecht HF: Meniere's disease: A correlation of symptomatology and pathology . Laryngoscope 1963;73:651-665.Crossref 17. Altmann F, Kornfeld M: Histological studies of Meniere's disease . Ann Otol Rhinol Laryngol 1965;74:915-944. 18. Schuknecht HF: Pathology of Meniere's disease . Otolaryngol Clin North Am 1968;1:331-337. 19. Schuknecht HF: Pathology of the Ear . Cambridge, Mass, Harvard University Press, 1974. 20. Alford BR: Meniere's disease: Criteria for diagnosis and evaluation of therapy for reporting . Trans Am Acad Ophthalmol Otolaryngol 1972;76:1462-1464. 21. Croxton FE, Cowden DJ: Applied General Statistics . Englewood Cliffs, NJ, Prentice-Hall, 1955. 22. Aran J-M: Clinical measures of VIIIth nerve function . Adv Otorhinolaryngol 1973; 20:374-394. 23. Coats AC, Martin JL: Human auditory nerve action potentials and brain stem evoked responses: Effects of audiogram shape and lesion location . Arch Otolaryngol 1977;103:605-622.Crossref 24. Dallos P, Schoeny ZG, Cheatman MA: Cochlear summating potentials . Acta Otolaryngol 1972;302:1-43. 25. Aran J-M, de Sauvage RC: Clinical value of cochlear microphonic recordings , in Ruben RJ, Elberling C, Salomon G (eds): Electrocochleography . Baltimore, University Park Press, 1976, pp 55-65.

Journal

Archives of OtolaryngologyAmerican Medical Association

Published: Apr 1, 1981

References