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The Significance of Jaundice In Acute Pancreatitis

The Significance of Jaundice In Acute Pancreatitis Abstract I. Introduction COMPLICATIONS which arise during the management of acute pancreatitis are numerous and complex. One particular problem is the coincidental presence of jaundice. From the files of the Los Angeles County Hospital, 300 autopsy records containing the diagnosis of acute pancreatitis were examined. Seventy-five (25%) of this group were found to have been jaundiced. The icterus was either recorded during the clinical course or the postmortem examination. II. Findings With Comment The Obstructed Group. —Obstruction of the common bile duct was the cause of jaundice in 31 or 41.3% of the 75 cases of acute pancreatitis with jaundice. Of these, 19 were due to calculi impacted in the choledochus or ampulla; ten were due to encroachment on the common bile duct by enlargement of the inflamed head of the pancreas; one was due to a carcinoma of the head of the pancreas; and one was the result of a References 1. Lium, R., and Maddock, S.: Etiology of Acute Pancreatitis , Surgery 24:593, 1948. 2. Rich, A. R., and Duff, G. L.: Experimental and Pathological Studies on Pathogenesis of Acute Hemorrhagic Pancreatic Pancreatitis , Bull Hopkins Hosp 58:212, 1936. 3. Wangensteen, O. H.; Leven, N. L.; and Manson, M. D.: Acute Pancreatitis: Experimental and Clinical Study, With Special Reference to Significance of Biliary Tract Factor , Arch Surg 23:470, 1931.Crossref 4. Ogilvie, R. F.: Duodenal Diverticula and Their Complications With Particular Reference to Acute Pancreatic Necrosis , Brit J Surg 28:362, 1941.Crossref 5. Hollinshead, W. H.: Lower Part of Common Bile Duct: Review , Surg Clin N Amer 37:939, 1957. 6. Hughes, E. S. R., and Kernutt, R. H.: Terminal Portion of Common Bile Duct and Pancreatic Duct of Wirsung , Aust New Zeal J Surg 23:223, 1954.Crossref 7. Rienhoff, W. F., Jr., and Pickerell, K. I.: Pancreatitis: Anatomic Study of Extrahepatic Biliary Systems , Arch Surg 51:205, 1945.Crossref 8. Sterling, J. A.: Common Channel for Bile and Pancreatic Ducts , Surg Gynec Obstet 98:420, 1954. 9. Ivy, A. C., and Gibbs, G. E.: Pancreatitis: Review , Surgery 31:614, 1952. 10. Thal, A. P.; Perry, J. F., Jr.; and Egner, W.: Clinical and Morphologic Study of Forty-two Cases of Fatal Acute Pancreatitis , Surg Gynec Obstet 105:191, 1957. 11. Weinstein, B. R.; Korn, R. J.; and Zimmerman, H. J.: Obstructive Jaundice as Complication of Pancreatitis , Ann Intern Med 58:245, 1963.Crossref 12. Cole, W. H.; Ireneus, C.; and Reynolds, J. T.: Strictures of Common Duct , Ann Surg 133:684, 1951.Crossref 13. Cattell, R. B.; Colcock, B. P.; and Pollack, J. L.: Stenosis of Sphincter of Oddi , New Eng J Med 256:429, 1957.Crossref 14. Stenson, J. C., Jr.; Baggenstoss, A. H.; and Morlock, C. G.: Pancreatic Lesions Associated With Cirrhosis of Liver , Amer J Clin Path 22:117, 1952. 15. Lindsay, S.; Entenman, C.; and Chaikoff, I. L.: Pancreatitis Accompanying Hepatic Disease is Dogs Fed High Fat, Low Protein Diet , Arch Path 45:635, 1948. 16. Woldman, E. E.: Fishman, D.; and Segal, A. J.: Relation to Fibrosis of Pancreas to Fatty Liver and/or Cirrhosis , JAMA 169:1281, 1959.Crossref 17. Newman, H. W., and Mehrtens, H. G.: Effect of Intravenous Injection of Ethyl Alcohol on Gastric Secretion in Man , Proc Soc Exp Biol Med 30:145, 1932.Crossref 18. Dragstedt, L. R.; Haymond, H. E.; and Ellis, J. C.: Pathogenesis of Acute Pancreatitis , Arch Surg 28:232, 1934.Crossref 19. McGowan, J. J.; Butsch, W.; and Walters, W.: Pressure in Common Bile Duct of Man in Relation to Pain Following Cholecystectomy , JAMA 106:2227, 1936.Crossref 20. Wiener, A. S.: Blood Groups and Transfusion , ed 3, Springfield, Ill: Charles C Thomas, Publisher, 1943. 21. Ackerman, L. V.: Acute Pancreatitis Following Blood Transfusion , Arch Path 34:1065, 1942. 22. McFarlane, R. G., and Biggs, R.: Fibrinolysis: Its Mechanism and Significance , Blood 3:1167, 1948. 23. Sanchez-Ubeda, R.; Rousselot, L. M.; and Gianelli, S.: Significance of Pancreatitis Accompanying Acute Cholecystitis , Ann Surg 144:44, 1956.Crossref 24. Hurvitz, S. A.; Averbook, B. D.; and Hurvitz, R. J.: Pancreatitis With Biliary Disease , Arch Surg 86:664, 1963.Crossref 25. Frieden, J. H.: Postoperative Acute Pancreatitis , Surg Gynec Obstet 102:139, 1956. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

The Significance of Jaundice In Acute Pancreatitis

Archives of Surgery , Volume 90 (3) – Mar 1, 1965

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Publisher
American Medical Association
Copyright
Copyright © 1965 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1965.01320090100023
Publisher site
See Article on Publisher Site

Abstract

Abstract I. Introduction COMPLICATIONS which arise during the management of acute pancreatitis are numerous and complex. One particular problem is the coincidental presence of jaundice. From the files of the Los Angeles County Hospital, 300 autopsy records containing the diagnosis of acute pancreatitis were examined. Seventy-five (25%) of this group were found to have been jaundiced. The icterus was either recorded during the clinical course or the postmortem examination. II. Findings With Comment The Obstructed Group. —Obstruction of the common bile duct was the cause of jaundice in 31 or 41.3% of the 75 cases of acute pancreatitis with jaundice. Of these, 19 were due to calculi impacted in the choledochus or ampulla; ten were due to encroachment on the common bile duct by enlargement of the inflamed head of the pancreas; one was due to a carcinoma of the head of the pancreas; and one was the result of a References 1. Lium, R., and Maddock, S.: Etiology of Acute Pancreatitis , Surgery 24:593, 1948. 2. Rich, A. R., and Duff, G. L.: Experimental and Pathological Studies on Pathogenesis of Acute Hemorrhagic Pancreatic Pancreatitis , Bull Hopkins Hosp 58:212, 1936. 3. Wangensteen, O. H.; Leven, N. L.; and Manson, M. D.: Acute Pancreatitis: Experimental and Clinical Study, With Special Reference to Significance of Biliary Tract Factor , Arch Surg 23:470, 1931.Crossref 4. Ogilvie, R. F.: Duodenal Diverticula and Their Complications With Particular Reference to Acute Pancreatic Necrosis , Brit J Surg 28:362, 1941.Crossref 5. Hollinshead, W. H.: Lower Part of Common Bile Duct: Review , Surg Clin N Amer 37:939, 1957. 6. Hughes, E. S. R., and Kernutt, R. H.: Terminal Portion of Common Bile Duct and Pancreatic Duct of Wirsung , Aust New Zeal J Surg 23:223, 1954.Crossref 7. Rienhoff, W. F., Jr., and Pickerell, K. I.: Pancreatitis: Anatomic Study of Extrahepatic Biliary Systems , Arch Surg 51:205, 1945.Crossref 8. Sterling, J. A.: Common Channel for Bile and Pancreatic Ducts , Surg Gynec Obstet 98:420, 1954. 9. Ivy, A. C., and Gibbs, G. E.: Pancreatitis: Review , Surgery 31:614, 1952. 10. Thal, A. P.; Perry, J. F., Jr.; and Egner, W.: Clinical and Morphologic Study of Forty-two Cases of Fatal Acute Pancreatitis , Surg Gynec Obstet 105:191, 1957. 11. Weinstein, B. R.; Korn, R. J.; and Zimmerman, H. J.: Obstructive Jaundice as Complication of Pancreatitis , Ann Intern Med 58:245, 1963.Crossref 12. Cole, W. H.; Ireneus, C.; and Reynolds, J. T.: Strictures of Common Duct , Ann Surg 133:684, 1951.Crossref 13. Cattell, R. B.; Colcock, B. P.; and Pollack, J. L.: Stenosis of Sphincter of Oddi , New Eng J Med 256:429, 1957.Crossref 14. Stenson, J. C., Jr.; Baggenstoss, A. H.; and Morlock, C. G.: Pancreatic Lesions Associated With Cirrhosis of Liver , Amer J Clin Path 22:117, 1952. 15. Lindsay, S.; Entenman, C.; and Chaikoff, I. L.: Pancreatitis Accompanying Hepatic Disease is Dogs Fed High Fat, Low Protein Diet , Arch Path 45:635, 1948. 16. Woldman, E. E.: Fishman, D.; and Segal, A. J.: Relation to Fibrosis of Pancreas to Fatty Liver and/or Cirrhosis , JAMA 169:1281, 1959.Crossref 17. Newman, H. W., and Mehrtens, H. G.: Effect of Intravenous Injection of Ethyl Alcohol on Gastric Secretion in Man , Proc Soc Exp Biol Med 30:145, 1932.Crossref 18. Dragstedt, L. R.; Haymond, H. E.; and Ellis, J. C.: Pathogenesis of Acute Pancreatitis , Arch Surg 28:232, 1934.Crossref 19. McGowan, J. J.; Butsch, W.; and Walters, W.: Pressure in Common Bile Duct of Man in Relation to Pain Following Cholecystectomy , JAMA 106:2227, 1936.Crossref 20. Wiener, A. S.: Blood Groups and Transfusion , ed 3, Springfield, Ill: Charles C Thomas, Publisher, 1943. 21. Ackerman, L. V.: Acute Pancreatitis Following Blood Transfusion , Arch Path 34:1065, 1942. 22. McFarlane, R. G., and Biggs, R.: Fibrinolysis: Its Mechanism and Significance , Blood 3:1167, 1948. 23. Sanchez-Ubeda, R.; Rousselot, L. M.; and Gianelli, S.: Significance of Pancreatitis Accompanying Acute Cholecystitis , Ann Surg 144:44, 1956.Crossref 24. Hurvitz, S. A.; Averbook, B. D.; and Hurvitz, R. J.: Pancreatitis With Biliary Disease , Arch Surg 86:664, 1963.Crossref 25. Frieden, J. H.: Postoperative Acute Pancreatitis , Surg Gynec Obstet 102:139, 1956.

Journal

Archives of SurgeryAmerican Medical Association

Published: Mar 1, 1965

References