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THE SENEAR-USHER SYNDROME: A DERMATOSIS COMBINING FEATURES OF LUPUS ERYTHEMATOSUS AND PEMPHIGUS

THE SENEAR-USHER SYNDROME: A DERMATOSIS COMBINING FEATURES OF LUPUS ERYTHEMATOSUS AND PEMPHIGUS Abstract In 1926, Senear and Usher1 published their report of "An Unusual Type of Pemphigus," which included a discussion of eleven cases of a hitherto undescribed clinical syndrome. Briefly, according to the authors' description, the clinical picture embraces features of both lupus erythematosus and pemphigus. The manifestations of the former disease involve the scalp and face, either with typical discoid patches and "carpet-tack" scales, or with an inflammatory reaction suggesting a severely congested seborrheic dermatitis. The lesions of pemphigus occur on the trunk, usually in the seborrheic areas, and consist of flaccid bullae that rupture readily and develop into areas of crusted, oozing dermatitis or into an inflammatory papule with a thick, greasy or even keratotic scale and crust. The lesions usually involute spontaneously and leave pigmented patches. The symptoms are mild; itching may occur, but the course is usually relatively benign. The cases in the original Senear-Usher group References 1. Senear, F. E., and Usher, B.: An Unusual Type of Pemphigus , Arch. Dermat. & Syph. 13:761 ( (June) ) 1926. 2. Wise, F., in discussion of Senear and Usher (footnote 1, p. 781). 3. Walzer, A.: Pemphigus , Arch. Dermat. & Syph. 13:445 ( (March) ) 1926. 4. Senear, F. E.: Pemphigus , Arch. Dermat. & Syph. 13:552 ( (April) ) 1926. 5. Grindon, J.: Unusual Form of Pemphigus Combining Features of Lupus Erythematosus (Senear) , Arch. Dermat. & Syph. 18:463 ( (Sept.) ) 1928. 6. Schamberg, J. F.: Lupus Erythematosus , Arch. Dermat. & Syph. 14:228 ( (Aug.) ) 1926. 7. O'Leary, P. A., and Goeckerman, W. H.: Chronic Lupus Erythematosus Disseminatus (Lupus Erythematosus—Pemphigus Syndrome of Ormsby and Senear) , Arch. Dermat. & Syph. 15:92 ( (Jan.) ) 1927. 8. Valade, C. K.: A Case for Diagnosis , Arch. Dermat. & Syph. 16:246 ( (Aug.) ) 1927. 9. Valade, C. K.: Report of a Case of Lupus Erythematosus in a Negress , J. Michigan M. Soc. 26:356 ( (June) ) 1927. 10. Davis, R. H., in discussion of Grindon (footnote 5, p. 464). 11. Fisher, J.: Pemphigus Resembling Lupus Erythematosus , Arch. Dermat. & Syph. 18:942 ( (Dec.) ) 1928. 12. Grau and Pelaez: Chronic Pemphigus , Arch. Dermat. & Syph. 19:823 ( (May) ) 1929. 13. Cole, H. N., and Driver, J. R.: Pemphigus (Senear Type?) , Arch. Dermat. & Syph. 20:140 ( (July) ) 1929. 14. Wile, U. J.: A Case for Diagnosis , Arch. Dermat. & Syph. 20:536 ( (Oct.) ) 1929. 15. Snider, M. C.: Case for Diagnosis , Arch. Dermat. & Syph. 20:558 ( (Oct.) ) 1929. 16. Pels, I. R., and Macht, D. I.: Phytopharmacologic Examination of the Blood in Pemphigus and in Some Other Diseases of the Skin , Arch. Dermat. & Syph. 19:640 ( (April) ) 1929. 17. Gilman, R. L.: Atypical Benign Pemphigus (with Features of Lupus Erythematosus as Described by Senear and Usher) , Arch. Dermat. & Syph. 21: 1078 ( (June) ) 1930. 18. Ormsby, O. H.: Diseases of the Skin , Philadelphia, Lea & Febiger, 1927, p. 305. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology and Syphilology American Medical Association

THE SENEAR-USHER SYNDROME: A DERMATOSIS COMBINING FEATURES OF LUPUS ERYTHEMATOSUS AND PEMPHIGUS

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Publisher
American Medical Association
Copyright
Copyright © 1931 American Medical Association. All Rights Reserved.
ISSN
0096-6029
DOI
10.1001/archderm.1931.01450010089006
Publisher site
See Article on Publisher Site

Abstract

Abstract In 1926, Senear and Usher1 published their report of "An Unusual Type of Pemphigus," which included a discussion of eleven cases of a hitherto undescribed clinical syndrome. Briefly, according to the authors' description, the clinical picture embraces features of both lupus erythematosus and pemphigus. The manifestations of the former disease involve the scalp and face, either with typical discoid patches and "carpet-tack" scales, or with an inflammatory reaction suggesting a severely congested seborrheic dermatitis. The lesions of pemphigus occur on the trunk, usually in the seborrheic areas, and consist of flaccid bullae that rupture readily and develop into areas of crusted, oozing dermatitis or into an inflammatory papule with a thick, greasy or even keratotic scale and crust. The lesions usually involute spontaneously and leave pigmented patches. The symptoms are mild; itching may occur, but the course is usually relatively benign. The cases in the original Senear-Usher group References 1. Senear, F. E., and Usher, B.: An Unusual Type of Pemphigus , Arch. Dermat. & Syph. 13:761 ( (June) ) 1926. 2. Wise, F., in discussion of Senear and Usher (footnote 1, p. 781). 3. Walzer, A.: Pemphigus , Arch. Dermat. & Syph. 13:445 ( (March) ) 1926. 4. Senear, F. E.: Pemphigus , Arch. Dermat. & Syph. 13:552 ( (April) ) 1926. 5. Grindon, J.: Unusual Form of Pemphigus Combining Features of Lupus Erythematosus (Senear) , Arch. Dermat. & Syph. 18:463 ( (Sept.) ) 1928. 6. Schamberg, J. F.: Lupus Erythematosus , Arch. Dermat. & Syph. 14:228 ( (Aug.) ) 1926. 7. O'Leary, P. A., and Goeckerman, W. H.: Chronic Lupus Erythematosus Disseminatus (Lupus Erythematosus—Pemphigus Syndrome of Ormsby and Senear) , Arch. Dermat. & Syph. 15:92 ( (Jan.) ) 1927. 8. Valade, C. K.: A Case for Diagnosis , Arch. Dermat. & Syph. 16:246 ( (Aug.) ) 1927. 9. Valade, C. K.: Report of a Case of Lupus Erythematosus in a Negress , J. Michigan M. Soc. 26:356 ( (June) ) 1927. 10. Davis, R. H., in discussion of Grindon (footnote 5, p. 464). 11. Fisher, J.: Pemphigus Resembling Lupus Erythematosus , Arch. Dermat. & Syph. 18:942 ( (Dec.) ) 1928. 12. Grau and Pelaez: Chronic Pemphigus , Arch. Dermat. & Syph. 19:823 ( (May) ) 1929. 13. Cole, H. N., and Driver, J. R.: Pemphigus (Senear Type?) , Arch. Dermat. & Syph. 20:140 ( (July) ) 1929. 14. Wile, U. J.: A Case for Diagnosis , Arch. Dermat. & Syph. 20:536 ( (Oct.) ) 1929. 15. Snider, M. C.: Case for Diagnosis , Arch. Dermat. & Syph. 20:558 ( (Oct.) ) 1929. 16. Pels, I. R., and Macht, D. I.: Phytopharmacologic Examination of the Blood in Pemphigus and in Some Other Diseases of the Skin , Arch. Dermat. & Syph. 19:640 ( (April) ) 1929. 17. Gilman, R. L.: Atypical Benign Pemphigus (with Features of Lupus Erythematosus as Described by Senear and Usher) , Arch. Dermat. & Syph. 21: 1078 ( (June) ) 1930. 18. Ormsby, O. H.: Diseases of the Skin , Philadelphia, Lea & Febiger, 1927, p. 305.

Journal

Archives of Dermatology and SyphilologyAmerican Medical Association

Published: Jul 1, 1931

References

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