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THE RENAL COMPLICATIONS OF HEMATIN INTOXICATION AND THEIR RELATION TO MALARIA

THE RENAL COMPLICATIONS OF HEMATIN INTOXICATION AND THEIR RELATION TO MALARIA Abstract Descriptions of the paroxysm1 and of the changes in the blood2 produced by the intravenous injection of alkaline hematin and their relation to human malaria have been presented in previous articles, and it is the object of this paper to add a third group of conditions which may properly be described as the renal complications of hematin intoxication. The description of these renal complications is based on a study of two classes of material : First, the urine and kidneys of a large series of rabbits, in which the production of renal lesions and disturbances of function were not the objects of the experiments, but were merely incidental; and second, twenty rabbits, in which the production of renal complications was made the prime object of the experiments. The hematin and hematin solutions used in these experiments were the same as in former experiments. The animals were fed, for References 1. Brown, Wade H.: Jour. Exper. Med. , 1912, xv, 579.Crossref 2. Brown, Wade H.: Jour. Exper. Med. , 1913, xviii. 3. Brown, Wade H.: Jour. Exper. Med. , 1911, xiii, 477.Crossref 4. Browicz: Virchows Arch. f. path. Anat. , 1900, clxii, 373.Crossref 5. Brown, Wade H., and Lovenhart, A. S.: Jour. Exper. Med. , 1913, xviii, (In press.) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

THE RENAL COMPLICATIONS OF HEMATIN INTOXICATION AND THEIR RELATION TO MALARIA

Archives of Internal Medicine , Volume XII (3) – Sep 1, 1913

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Publisher
American Medical Association
Copyright
Copyright © 1913 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1913.00070030072007
Publisher site
See Article on Publisher Site

Abstract

Abstract Descriptions of the paroxysm1 and of the changes in the blood2 produced by the intravenous injection of alkaline hematin and their relation to human malaria have been presented in previous articles, and it is the object of this paper to add a third group of conditions which may properly be described as the renal complications of hematin intoxication. The description of these renal complications is based on a study of two classes of material : First, the urine and kidneys of a large series of rabbits, in which the production of renal lesions and disturbances of function were not the objects of the experiments, but were merely incidental; and second, twenty rabbits, in which the production of renal complications was made the prime object of the experiments. The hematin and hematin solutions used in these experiments were the same as in former experiments. The animals were fed, for References 1. Brown, Wade H.: Jour. Exper. Med. , 1912, xv, 579.Crossref 2. Brown, Wade H.: Jour. Exper. Med. , 1913, xviii. 3. Brown, Wade H.: Jour. Exper. Med. , 1911, xiii, 477.Crossref 4. Browicz: Virchows Arch. f. path. Anat. , 1900, clxii, 373.Crossref 5. Brown, Wade H., and Lovenhart, A. S.: Jour. Exper. Med. , 1913, xviii, (In press.)

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Sep 1, 1913

References