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The Regulatory Challenge of Electronic Cigarettes

The Regulatory Challenge of Electronic Cigarettes VIEWPOINT Electronic cigarettes (e-cigarettes or electronic Product Evolution Neal L. Benowitz, MD nicotine delivery systems) heat a nicotine solution to More than 250 e-cigarette brands are on the market Division of Clinical Pharmacology and generate vapor that is inhaled, without the combus- currently, and products have evolved rapidly in recent Experimental tion of tobacco and its toxic constituents. Use of years. Different e-cigarette brands are engineered dif- Therapeutics, e-cigarettes is increasing in the United States and ferently, affecting the character and potential toxicity Departments of Medicine, around the world. Current smokers in the United of the vapor. Thus, it is difficult to generalize about Bioengineering, and States report an 11.4% prevalence of ever use of e-cigarettes as a single device. The FDA will need to Therapeutic Sciences, e-cigarettes and 4.1% use in past 30 days. They likely consider the engineering of e-cigarettes with respect to Medical Service, San pose less direct hazard to the individual smoker than different types of nicotine solutions, the capacity of the Francisco General Hospital Medical tobacco cigarettes and might help smokers quit smok- cartridges containing the solution, the nature of the Center, University of ing or reduce harm by smoking fewer tobacco ciga- heating http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

The Regulatory Challenge of Electronic Cigarettes

Benowitz, Neal L.; Goniewicz, Maciej L.
JAMA , Volume 310 (7) – Aug 21, 2013
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Publisher
American Medical Association
Copyright
Copyright 2013 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2013.109501
pmid
23856948
Publisher site
See Article on Publisher Site

Abstract

VIEWPOINT Electronic cigarettes (e-cigarettes or electronic Product Evolution Neal L. Benowitz, MD nicotine delivery systems) heat a nicotine solution to More than 250 e-cigarette brands are on the market Division of Clinical Pharmacology and generate vapor that is inhaled, without the combus- currently, and products have evolved rapidly in recent Experimental tion of tobacco and its toxic constituents. Use of years. Different e-cigarette brands are engineered dif- Therapeutics, e-cigarettes is increasing in the United States and ferently, affecting the character and potential toxicity Departments of Medicine, around the world. Current smokers in the United of the vapor. Thus, it is difficult to generalize about Bioengineering, and States report an 11.4% prevalence of ever use of e-cigarettes as a single device. The FDA will need to Therapeutic Sciences, e-cigarettes and 4.1% use in past 30 days. They likely consider the engineering of e-cigarettes with respect to Medical Service, San pose less direct hazard to the individual smoker than different types of nicotine solutions, the capacity of the Francisco General Hospital Medical tobacco cigarettes and might help smokers quit smok- cartridges containing the solution, the nature of the Center, University of ing or reduce harm by smoking fewer tobacco ciga- heating

Journal

JAMA – American Medical Association

Published: Aug 21, 2013

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