Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

THE RÔLE OF HEMOLYSIS IN JAUNDICE OF THE NEW-BORN INFANT

THE RÔLE OF HEMOLYSIS IN JAUNDICE OF THE NEW-BORN INFANT In 1882, Hofmeier1 first suggested a hematogenous origin for jaundice of the new-born infant. For years this theory received little attention, but evidence gradually accumulated which led writers on the subject to grant it a rôle of minor importance, then to assign it a parity with hepatogenous factors, and finally to advance it as the sole cause of this condition. In 1912, Hess2 dismissed blood destruction as being a primary cause of jaundice, on the following grounds: First, when the liver is extirpated, jaundice cannot be induced; second, the finding of bile acids in the pericardial fluid of jaundiced babies proves the participation of the liver; third, free hemoglobin cannot be found in the blood of the new-born infant; fourth, jaundice cannot be produced by the injection of hemoglobin, and fifth, jaundice does not follow transfusion. Today each of these objections can be met. Whipple and Hooper3 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

THE RÔLE OF HEMOLYSIS IN JAUNDICE OF THE NEW-BORN INFANT

Loading next page...
 
/lp/american-medical-association/the-r-le-of-hemolysis-in-jaundice-of-the-new-born-infant-GEqe6KLXdD

References (16)

Publisher
American Medical Association
Copyright
Copyright © 1928 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1928.01920270063007
Publisher site
See Article on Publisher Site

Abstract

In 1882, Hofmeier1 first suggested a hematogenous origin for jaundice of the new-born infant. For years this theory received little attention, but evidence gradually accumulated which led writers on the subject to grant it a rôle of minor importance, then to assign it a parity with hepatogenous factors, and finally to advance it as the sole cause of this condition. In 1912, Hess2 dismissed blood destruction as being a primary cause of jaundice, on the following grounds: First, when the liver is extirpated, jaundice cannot be induced; second, the finding of bile acids in the pericardial fluid of jaundiced babies proves the participation of the liver; third, free hemoglobin cannot be found in the blood of the new-born infant; fourth, jaundice cannot be produced by the injection of hemoglobin, and fifth, jaundice does not follow transfusion. Today each of these objections can be met. Whipple and Hooper3

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Sep 1, 1928

There are no references for this article.