THE PROPHYLAXIS OF RHEUMATIC FEVER
Abstract
Although some evidence1 tends to show that sulfanilamide is without therapeutic effect (and may even be dangerous) in the treatment of rheumatic fever, the reports of Thomas and France2 in Baltimore and of Coburn and Moore3 in New York have indicated that the drug may be of prophylactic value in preventing the recurrence of rheumatic attacks. Its experimental use for this purpose was based on the series of observations made by Coburn during the past decade, which relate rheumatic...