Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

THE OVARIAN FOLLICULAR HORMONE

THE OVARIAN FOLLICULAR HORMONE In earlier work1 it has been demonstrated that lipoid extracts of the contents of ovarian follicles quite completely substitute for certain phases of the internal secretion of the ovaries. This was done by injecting extracts of material from pig ovaries into rats and mice from which the ovaries had previously been removed. The action of the follicular hormone includes the production of striking growth in the female genital organs. The rapidity of this growth in the test animals is astonishing. An entirely new epithelial wall is produced in the vagina in forty-eight hours. This involves the addition of more than twelve layers of new cells (Fig. 2, in which A, the control animal, is to be compared with B and C, injected animals). In the uterus a corresponding growth occurs and the secretion of the glands, which is retained in these animals by cervical constriction, greatly distends the uterus http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

THE OVARIAN FOLLICULAR HORMONE

JAMA , Volume 85 (6) – Aug 8, 1925

Loading next page...
 
/lp/american-medical-association/the-ovarian-follicular-hormone-LdfyhgmFka
Publisher
American Medical Association
Copyright
Copyright © 1925 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1925.02670060001001
Publisher site
See Article on Publisher Site

Abstract

In earlier work1 it has been demonstrated that lipoid extracts of the contents of ovarian follicles quite completely substitute for certain phases of the internal secretion of the ovaries. This was done by injecting extracts of material from pig ovaries into rats and mice from which the ovaries had previously been removed. The action of the follicular hormone includes the production of striking growth in the female genital organs. The rapidity of this growth in the test animals is astonishing. An entirely new epithelial wall is produced in the vagina in forty-eight hours. This involves the addition of more than twelve layers of new cells (Fig. 2, in which A, the control animal, is to be compared with B and C, injected animals). In the uterus a corresponding growth occurs and the secretion of the glands, which is retained in these animals by cervical constriction, greatly distends the uterus

Journal

JAMAAmerican Medical Association

Published: Aug 8, 1925

There are no references for this article.