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THE ORAL USE OF CORTISONE SUSPENSION IN SYRUP

THE ORAL USE OF CORTISONE SUSPENSION IN SYRUP In June 1950, Freyberg1 and Hench2 independently announced the efficacy of cortisone tablets. Later, Freyberg and associates3 published the results of treatment with cortisone tablets in four patients. It was apparent that a suspension of cortisone taken orally should be absorbed from the gastrointestinal tract as readily as cortisone taken in tablet form. Moreover, tablets of cortisone were not generally available at the time. Accordingly, we used cortisone suspension by mouth in order to evaluate the efficacy of the oral route of administration. This preliminary report is based on our experience with 29 patients selected from the medical wards of the Veterans Administration Hospital, San Francisco, and from private practice. Each patient had a disease known to respond favorably to cortisone and severe enough to warrant the use of the hormone. METHOD OF ORAL ADMINISTRATION OF CORTISONE SUSPENSION The injectable suspension of cortisone has a highly disagreeable http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

THE ORAL USE OF CORTISONE SUSPENSION IN SYRUP

JAMA , Volume 145 (6) – Feb 10, 1951

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Publisher
American Medical Association
Copyright
Copyright © 1951 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1951.72920240004009b
Publisher site
See Article on Publisher Site

Abstract

In June 1950, Freyberg1 and Hench2 independently announced the efficacy of cortisone tablets. Later, Freyberg and associates3 published the results of treatment with cortisone tablets in four patients. It was apparent that a suspension of cortisone taken orally should be absorbed from the gastrointestinal tract as readily as cortisone taken in tablet form. Moreover, tablets of cortisone were not generally available at the time. Accordingly, we used cortisone suspension by mouth in order to evaluate the efficacy of the oral route of administration. This preliminary report is based on our experience with 29 patients selected from the medical wards of the Veterans Administration Hospital, San Francisco, and from private practice. Each patient had a disease known to respond favorably to cortisone and severe enough to warrant the use of the hormone. METHOD OF ORAL ADMINISTRATION OF CORTISONE SUSPENSION The injectable suspension of cortisone has a highly disagreeable

Journal

JAMAAmerican Medical Association

Published: Feb 10, 1951

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