Abstract • Background.— Dermatologists are often confronted with neoplasms and diseases of the oral cavity. Although many may be reluctant to perform oral surgical procedures, a biopsy is often needed to establish a definitive diagnosis. This article describes a simple and safe method of obtaining an oral biopsy specimen. Observations.— A punch was used in performing 140 biopsies from various locations of the oral cavity. Bleeding was controlled by pressure in the majority of cases, with only a few requiring electrodesiccation. Biopsy sites, all of which were left to heal by secondary intention, showed almost complete reepithelialization at a 2-week postoperative check. Complications from surgery were almost nonexistent and minor in degree. Conclusions.— The punch biopsy of the oral cavity is a safe and useful technique that can be easily employed by dermatologists. Biopsies should be kept superficial, and neurovascular structures must be avoided to prevent complications.(Arch Dermatol. 1992;128:815-817) References 1. Laskaris G, Sklavounou A, Stratigos J. Bullous pemphigoid, cicatricial pemphigoid and pemphigus vulgaris: a comparative clinical survey of 278 cases . Oral Surg. 1982;54:656-662.Crossref 2. Krull EA, Wolford GA. Surgical approaches to oral lesions . Dermatol Clin. 1987;5:723-731. 3. Roth RJ. An instrument and a technique to facilitate biopsies of lesions of the structures of the mouth and within the oral cavity . J Dermatol Surg Oncol. 1982;7:861-862. 4. Ceilley R. Biopsy technique for oral lesions . J Dermatol Surg Oncol. 1979;5:88-89.Crossref 5. Bertram V, Hjorting-Hansen E. Punch biopsy of minor salivary glands in the diagnosis of Sjögren's syndrome . Scand J Dent Res. 1970;78:295-300. 6. Baker HW. Biopsy: definitive diagnosis of oral cancer . CA . 1972;22:159-162. 7. Lynch DP, Morris LF. The oral mucosal punch biopsy: indicators and technique . J Am Dent Assoc. 1990;12:145-149. 8. Westbrook JL, Lucas R. Oral biopsy, application, rationale, and technique . Temple Dent Rev. 1973;43:7-8. 9. Stern M. Oral tumors, including biopsy techniques . Dent Clin North Am. 1971;15:423-432. 10. Black MM, Bhogal BS, Willstead E. Immunopathological techniques in the diagnosis of bullous disorders . Acta Dermatol Venereol. 1989;151:96-105. 11. Bentley KC. Oral biopsies and cytological smears . J Can Dent Assoc. 1974;3:218-220. 12. Daley TD, Lovas JL, Wysocki GP. Oral biopsy technique: the pathologist's perspective . J Can Dent Assoc. 1986;52:591-595. 13. Baughman RA. Understanding and diagnosing oral disease. Biopsy—when and how? Fla Dent J. 1973;44:23-24. 14. Steidler NE, Reade PC, Radden BG. Malignant melanoma of the oral mucosa . J Oral Maxillofac Surg. 1984;42:333-336.Crossref
Archives of Dermatology – American Medical Association
Published: Jun 1, 1992
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