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The Nevus of Ota or Oculodermal Melanocytosis: The Ocular Changes

The Nevus of Ota or Oculodermal Melanocytosis: The Ocular Changes Abstract Introduction A unique oculocutaneous pigmentation characterized by benign mesodermal melanosis of the paraocular skin and usually the sclera and other ocular tissues was first described and defined as an entity by Ota18 and Ota and Tanino,19 under the name of nevus fuscocoeruleus maxillofacialis. Subsequent authors have called it nevus fuscocoeruleus maxillo-facialis of Ota, or, simply, the nevus of Ota. The latter name is the most often used. The terms oculocutaneous melanosis and oculodermal melanocytosis have also been coined to designate the condition. The former of these, we feel, is too easily confused with melanosis oculi, a different condition, as described by Reese.22,23 The latter, proposed by Fitzpatrick,9 although graphic, is not widely used. Most of the literature pertaining to this subject has been presented from the dermatologic standpoint and the ocular findings have been, with certain exceptions, incompletely reported. It is the purpose of this paper References 1. Aubry; Boulard; Larmonde, and Chevrot: Un Cas de naevus melanique ophthalmo-maxillaire avec hemiatrophie faciale L'Algerie Medicale, No. 7, pp. 265-267 (Aug.-Sept.) 1949. 2. Bozzoni, F., and Bozzoni, G.: Two Cases of Ota's Syndrome or Oculodermic Melanocytosis , Boll. Oculist. 36:652-657 ( (Oct.) ) 1957. 3. Brennemann, J.: The Sacral or So-Called "Mongolian" Pigmented Spots of Earliest Infancy and Childhood with Especial Reference to their Occurrence in the American Negro , Arch. Pediat. 24:426-444 ( (June) ) 1907. 4. Carleton, A., and Biggs, R.: Diffuse Mesodermal Pigmentation with Congenital Abnormality , Brit. J. Derm. 60:10-13 ( (Jan.) ) 1948.Crossref 5. Cole, H. N., Jr.; Hubler, W. R., and Lund., H. Z.: Persistant Aberrant Mongolian Spots , Arch. Derm. Syph. 61:244-260 ( (Feb.) ) 1950.Crossref 6. Dorsey, C. S., and Montgomery, H.: Blue Nevus and Its Distinction from Mongolian Spot and the Nevus of Ota , J. Invest. Derm. 22:225-236 ( (March) ) 1954.Crossref 7. Duperrat, B., and Miller, H. A.: Deux Cas de naevus fusco-coeruleus ophthalmo-maxillaris de Ota , Bull. Soc. Ophthal. Franc. 486-489 ( (Oct.) ) 1954. 8. Findlay, G. H., and Rand, W. W.: Mesodermal Melanosis of the Face and Sclera , S. Afr. J. Clin. Sci. 2:281-287 ( (Dec.) ) 1951. 9. Fitzpatrick, T. B.; Zeller, R.; Kukita, A., and Kitamura, H.: Ocular and Dermal Melanocytosis , A.M.A. Arch. Ophthal. 56:830-832 ( (Dec.) ) 1956.Crossref 10. Hadida, E., and Streit, R.: Nevus Fusco-Coeruleus , Bull. Soc. Franc. Dermat. Syph. 64: 399-400 ( (Aug.-Oct.) ) 1957. 11. Helmick, E. D., and Pringle, R. W.: Oculo-Cutaneous Melanosis or Nevus of Ota , A.M.A. Arch. Ophthal. 56:833-838 ( (Dec.) ) 1956.Crossref 12. Hidano, A.; Kazuo, N.; Mishima, Y.: Pigmentation des muqueses dans le naevus d'Ota , Bull. Soc. Franc. Dermat. Syph. 64:287-288 ( (June-July) ) 1957. 13. Ito, M.: Studies on Melanin: XI. Further Contribution on the Pigment-Bearing Cells in Mongolian Spot and Blue Nevus , Tohoku J. Exp. Med. 54:181-187 ( (June) ) 1951.Crossref 14. Ito, M.: Genesis of Mongolian Spot and Blue Nevus , Tohoku J. Exp. Med. (Suppl. 1) , pp. 21-29 (Feb.) 1952. 15. Jensen, C. D. F., and Haffly, G. N.: An Unusual Case of Progressive Melanosis Oculi , Amer. J. Ophthal. 31:1476 ( (Nov.) ) 1948. 16. Kersting, D. W., and Caro, M. R.: Cellular Blue Nevus of Ota Followed for 22 Years , A.M.A. Arch. Derm. 74:59-62 ( (July) ) 1956.Crossref 17. Montgomery, H., and Kahler, J. E.: The Blue Nevus (Jadassohn-Friche): Its Distinction from Ordinary Moles and Malignant Melanomas , Amer. J. Cancer 36:527-539 ( (Aug.) ) 1939. 18. Ota, M.: Navus Fusco-caeruleus Ophthalmomaxillaris , Tokyo Med. J. 63:1243-1245, 1939. 19. Ota, M., and Tanino, H.: Über ein in Japan sehr häufig vorkommende Navus Form, Navus Fusco-caeruleus Ophthalmo-maxillaris, und ihre Beziehungen zu der Augenmelanose , Jap. J. Derm. Urol. 45:119-120 ( (May) ) 1939. 20. Pariser, H., and Beerman, H.: Extensive Blue Patchlike Pigmentation , Arch. Derm. Syph. 59:396-404 ( (April) ) 1949.Crossref 21. Pusey, W. A.: Facial Pigmentation Involving the Sclera , Ophthal. Rec. 25:618 ( (Dec.) ) 1916. 22. Reese, A. B.: Melanosa Oculi: A Case with Microscopic Findings , Amer. J. Ophthal. 8: 865-870 ( (Nov.) ) 1925. 23. Reese, A. B.: Tumors of the Eye , New York, Paul B. Hoeber Inc. (medical book department of Harper & Brothers) 1951, pp. 226-229, 339. 24. Rochat, G. F., Jr.: Un Cas de melanose congenitale d l'oeil , Ophthalmologica 99:481-483 ( (May) ) 1940.Crossref 25. Rothman, S., and Pinne, G.: Blue Nevus of the Eye and Melanosis of the Temple (Due to Contact with Telephone Receiver?) , Arch. Derm. Syph. 58:550 ( (Nov.) ) 1948. 26. Rozan, A.; Lacrous, R.; Pernod, J.; Memim, Y.; Bouchat, J.; Poirier, J. P: Un Cas de naevus fusco-coeruleus ophthalmo-maxillaris (Naevus d'Ota) , Bull. Soc. Ophthal. Franc. 245-250 ( (April) ) 1959. 27. Tanino, H.: Über eine in Japan häufig vorkommende Navus Form: Nävus Fusco-caeruleus Ophthalmo-maxillaris (Ota): Part I Mitteilung: Beobachtung über Lokalization verfarbung und histologische Veränderung , Jap. J. Dermat. Urol. 46:107-111, 1939 28. Part II Mitteilung: Beobachtungen über die Augenmelanose als Komplikation dieses Navus und seine klinische Erscheinung , Jap. J. Dermat. Urol. 47:51-53 ( (March) ) 1940. 29. Voisin, J.; Bolgert, M.; Reboul, R., Cottenot, F.: Melanose congenitale de la scleratoque avec extension tardive a la surface cutanée , Bull. Soc. Ophthal. Franc. , pp. 58-61, 1950. 30. Yoshida, K.: Nevus Fusco-Caeruleus Ophthalmo-maxillaris Ota , Tohoku J.. Exp. Med. ( (Suppl. 1) ) 55:34-43, 1952.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

The Nevus of Ota or Oculodermal Melanocytosis: The Ocular Changes

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Publisher
American Medical Association
Copyright
Copyright © 1961 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1961.01840020485004
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Abstract

Abstract Introduction A unique oculocutaneous pigmentation characterized by benign mesodermal melanosis of the paraocular skin and usually the sclera and other ocular tissues was first described and defined as an entity by Ota18 and Ota and Tanino,19 under the name of nevus fuscocoeruleus maxillofacialis. Subsequent authors have called it nevus fuscocoeruleus maxillo-facialis of Ota, or, simply, the nevus of Ota. The latter name is the most often used. The terms oculocutaneous melanosis and oculodermal melanocytosis have also been coined to designate the condition. The former of these, we feel, is too easily confused with melanosis oculi, a different condition, as described by Reese.22,23 The latter, proposed by Fitzpatrick,9 although graphic, is not widely used. Most of the literature pertaining to this subject has been presented from the dermatologic standpoint and the ocular findings have been, with certain exceptions, incompletely reported. It is the purpose of this paper References 1. Aubry; Boulard; Larmonde, and Chevrot: Un Cas de naevus melanique ophthalmo-maxillaire avec hemiatrophie faciale L'Algerie Medicale, No. 7, pp. 265-267 (Aug.-Sept.) 1949. 2. Bozzoni, F., and Bozzoni, G.: Two Cases of Ota's Syndrome or Oculodermic Melanocytosis , Boll. Oculist. 36:652-657 ( (Oct.) ) 1957. 3. Brennemann, J.: The Sacral or So-Called "Mongolian" Pigmented Spots of Earliest Infancy and Childhood with Especial Reference to their Occurrence in the American Negro , Arch. Pediat. 24:426-444 ( (June) ) 1907. 4. Carleton, A., and Biggs, R.: Diffuse Mesodermal Pigmentation with Congenital Abnormality , Brit. J. Derm. 60:10-13 ( (Jan.) ) 1948.Crossref 5. Cole, H. N., Jr.; Hubler, W. R., and Lund., H. Z.: Persistant Aberrant Mongolian Spots , Arch. Derm. Syph. 61:244-260 ( (Feb.) ) 1950.Crossref 6. Dorsey, C. S., and Montgomery, H.: Blue Nevus and Its Distinction from Mongolian Spot and the Nevus of Ota , J. Invest. Derm. 22:225-236 ( (March) ) 1954.Crossref 7. Duperrat, B., and Miller, H. A.: Deux Cas de naevus fusco-coeruleus ophthalmo-maxillaris de Ota , Bull. Soc. Ophthal. Franc. 486-489 ( (Oct.) ) 1954. 8. Findlay, G. H., and Rand, W. W.: Mesodermal Melanosis of the Face and Sclera , S. Afr. J. Clin. Sci. 2:281-287 ( (Dec.) ) 1951. 9. Fitzpatrick, T. B.; Zeller, R.; Kukita, A., and Kitamura, H.: Ocular and Dermal Melanocytosis , A.M.A. Arch. Ophthal. 56:830-832 ( (Dec.) ) 1956.Crossref 10. Hadida, E., and Streit, R.: Nevus Fusco-Coeruleus , Bull. Soc. Franc. Dermat. Syph. 64: 399-400 ( (Aug.-Oct.) ) 1957. 11. Helmick, E. D., and Pringle, R. W.: Oculo-Cutaneous Melanosis or Nevus of Ota , A.M.A. Arch. Ophthal. 56:833-838 ( (Dec.) ) 1956.Crossref 12. Hidano, A.; Kazuo, N.; Mishima, Y.: Pigmentation des muqueses dans le naevus d'Ota , Bull. Soc. Franc. Dermat. Syph. 64:287-288 ( (June-July) ) 1957. 13. Ito, M.: Studies on Melanin: XI. Further Contribution on the Pigment-Bearing Cells in Mongolian Spot and Blue Nevus , Tohoku J. Exp. Med. 54:181-187 ( (June) ) 1951.Crossref 14. Ito, M.: Genesis of Mongolian Spot and Blue Nevus , Tohoku J. Exp. Med. (Suppl. 1) , pp. 21-29 (Feb.) 1952. 15. Jensen, C. D. F., and Haffly, G. N.: An Unusual Case of Progressive Melanosis Oculi , Amer. J. Ophthal. 31:1476 ( (Nov.) ) 1948. 16. Kersting, D. W., and Caro, M. R.: Cellular Blue Nevus of Ota Followed for 22 Years , A.M.A. Arch. Derm. 74:59-62 ( (July) ) 1956.Crossref 17. Montgomery, H., and Kahler, J. E.: The Blue Nevus (Jadassohn-Friche): Its Distinction from Ordinary Moles and Malignant Melanomas , Amer. J. Cancer 36:527-539 ( (Aug.) ) 1939. 18. Ota, M.: Navus Fusco-caeruleus Ophthalmomaxillaris , Tokyo Med. J. 63:1243-1245, 1939. 19. Ota, M., and Tanino, H.: Über ein in Japan sehr häufig vorkommende Navus Form, Navus Fusco-caeruleus Ophthalmo-maxillaris, und ihre Beziehungen zu der Augenmelanose , Jap. J. Derm. Urol. 45:119-120 ( (May) ) 1939. 20. Pariser, H., and Beerman, H.: Extensive Blue Patchlike Pigmentation , Arch. Derm. Syph. 59:396-404 ( (April) ) 1949.Crossref 21. Pusey, W. A.: Facial Pigmentation Involving the Sclera , Ophthal. Rec. 25:618 ( (Dec.) ) 1916. 22. Reese, A. B.: Melanosa Oculi: A Case with Microscopic Findings , Amer. J. Ophthal. 8: 865-870 ( (Nov.) ) 1925. 23. Reese, A. B.: Tumors of the Eye , New York, Paul B. Hoeber Inc. (medical book department of Harper & Brothers) 1951, pp. 226-229, 339. 24. Rochat, G. F., Jr.: Un Cas de melanose congenitale d l'oeil , Ophthalmologica 99:481-483 ( (May) ) 1940.Crossref 25. Rothman, S., and Pinne, G.: Blue Nevus of the Eye and Melanosis of the Temple (Due to Contact with Telephone Receiver?) , Arch. Derm. Syph. 58:550 ( (Nov.) ) 1948. 26. Rozan, A.; Lacrous, R.; Pernod, J.; Memim, Y.; Bouchat, J.; Poirier, J. P: Un Cas de naevus fusco-coeruleus ophthalmo-maxillaris (Naevus d'Ota) , Bull. Soc. Ophthal. Franc. 245-250 ( (April) ) 1959. 27. Tanino, H.: Über eine in Japan häufig vorkommende Navus Form: Nävus Fusco-caeruleus Ophthalmo-maxillaris (Ota): Part I Mitteilung: Beobachtung über Lokalization verfarbung und histologische Veränderung , Jap. J. Dermat. Urol. 46:107-111, 1939 28. Part II Mitteilung: Beobachtungen über die Augenmelanose als Komplikation dieses Navus und seine klinische Erscheinung , Jap. J. Dermat. Urol. 47:51-53 ( (March) ) 1940. 29. Voisin, J.; Bolgert, M.; Reboul, R., Cottenot, F.: Melanose congenitale de la scleratoque avec extension tardive a la surface cutanée , Bull. Soc. Ophthal. Franc. , pp. 58-61, 1950. 30. Yoshida, K.: Nevus Fusco-Caeruleus Ophthalmo-maxillaris Ota , Tohoku J.. Exp. Med. ( (Suppl. 1) ) 55:34-43, 1952.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Apr 1, 1961

References