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Editorials represent the opinions EDITORIAL of the authors and JAMA and not those of the American Medical Association. A Hidden Public Health Disaster? Americans, for whom they had detailed information on physi- Derek C. Angus, MD, MPH cal and neurocognitive function both before and after an epi- sode of sepsis. The authors identified sepsis by screening EPSIS, THE SYNDROME OF INFECTION COMPLICATED BY all hospitalizations between 1998 and 2005 in the subset of vital organ dysfunction, is a medical emergency that participants for whom Medicare claims data were avail- affects more than 750 000 patients in the United States able. The diagnosis of sepsis is not easy to establish, espe- Seach year and remains one of the world’s leading 1 cially using claims data. The authors used an existing diag- causes of death. Without prompt resuscitation, antibiot- nostic scheme that others have applied ; this approach is ics, and institution of life support, patients can quickly de- by no means perfect, but it identifies patients similar to those velop shock, multisystem organ failure, and death. It is not detected by prospectively trained clinical study coordina- surprising, therefore, that the main goal of care and of re- tors. search has
JAMA – American Medical Association
Published: Oct 27, 2010
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