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THE INTRACUTANEOUS QUANTITATIVE TUBERCULIN TEST

THE INTRACUTANEOUS QUANTITATIVE TUBERCULIN TEST The diagnosis of active tuberculosis is aided but little by the positive skin tuberculin test (Pirquet or Mantoux tests), for more than 90 per cent of healthy adults will react positively to this test. On the other hand, the diagnosis of active tuberculosis can be made in more than 90 per cent of people who have positive skin reactions after the intracutaneous injection of properly diluted tuberculin, according to recent reports. The present study has attempted to determine further the value of such a test with diluted tuberculin. RATIONALE OF SUCH A TEST The use of the dilute tuberculin reaction is based on the following simplified interpretation of experimental and clinical evidence: Past or present infection with tuberculosis makes the individual sensitive to tuberculin. One way of demonstrating this sensitivity is by a positive skin reaction following the usual skin injection of Koch's old tuberculin (Pirquet scratch method or Mantoux http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

THE INTRACUTANEOUS QUANTITATIVE TUBERCULIN TEST

AYMAN, DAVID
JAMA , Volume 103 (3) – Jul 21, 1934
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References (2)

Publisher
American Medical Association
Copyright
Copyright © 1934 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1934.02750290004002
Publisher site
See Article on Publisher Site

Abstract

The diagnosis of active tuberculosis is aided but little by the positive skin tuberculin test (Pirquet or Mantoux tests), for more than 90 per cent of healthy adults will react positively to this test. On the other hand, the diagnosis of active tuberculosis can be made in more than 90 per cent of people who have positive skin reactions after the intracutaneous injection of properly diluted tuberculin, according to recent reports. The present study has attempted to determine further the value of such a test with diluted tuberculin. RATIONALE OF SUCH A TEST The use of the dilute tuberculin reaction is based on the following simplified interpretation of experimental and clinical evidence: Past or present infection with tuberculosis makes the individual sensitive to tuberculin. One way of demonstrating this sensitivity is by a positive skin reaction following the usual skin injection of Koch's old tuberculin (Pirquet scratch method or Mantoux

Journal

JAMA – American Medical Association

Published: Jul 21, 1934

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