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The Impact of Birth Defects and Genetic Diseases

The Impact of Birth Defects and Genetic Diseases Abstract PROBABLY MOST pediatricians do not realize that birth defects are the leading cause of infant mortality in North America. During the last few decades, enormous progress has been made in the treatment and prevention of infectious diseases through improved antibiotics and more effective immunization; sudden infant death has been associated with the sleeping position, and, by altering the sleeping position, the occurrence of sudden infant death has been decreased. Prematurity can now be prevented and treated more effectively with surfactant, corticosteroids, and a variety of other interventions. Thus, congenital anomalies have become the most frequent cause of infant death. For infants with genetic disease and congenital anomalies who do not die, enormous morbidity, long-term effects on their families, and many hospitalizations are characteristic. The article by Yoon et al1 in this issue of the Archives makes it quite clear that we have a great deal to learn to properly References 1. Yoon PW, Olney RS, Khoury MJ, Sappenfield WM, Chavez GF, Taylor D. Contribution of birth defects and genetic diseases to pediatric hospitalizations: a population-based study . Arch Pediatr Adolesc Med . 1997;151:1096-1103.Crossref 2. Pearce HR. Periconceptual folic acid: knowledge amongst patients and health care workers in a London teaching hospital . Br J Fam Plann . 1996;22:20-21. 3. Forman R, Singal N, Perelman V, et al. Folic acid and prevention of neural tube defects: a study of Canadian mothers of infants with spina bifida . Clin Invest Med . 1996;19:195-201. 4. Knowledge and use of folic acid by women of childbearing age: United States, 1995 . MMWR Morb Mortal Wkly Rep . 1995;44:716-718. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Pediatrics & Adolescent Medicine American Medical Association

The Impact of Birth Defects and Genetic Diseases

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References (4)

Publisher
American Medical Association
Copyright
Copyright © 1997 American Medical Association. All Rights Reserved.
ISSN
1072-4710
eISSN
1538-3628
DOI
10.1001/archpedi.1997.02170480012002
Publisher site
See Article on Publisher Site

Abstract

Abstract PROBABLY MOST pediatricians do not realize that birth defects are the leading cause of infant mortality in North America. During the last few decades, enormous progress has been made in the treatment and prevention of infectious diseases through improved antibiotics and more effective immunization; sudden infant death has been associated with the sleeping position, and, by altering the sleeping position, the occurrence of sudden infant death has been decreased. Prematurity can now be prevented and treated more effectively with surfactant, corticosteroids, and a variety of other interventions. Thus, congenital anomalies have become the most frequent cause of infant death. For infants with genetic disease and congenital anomalies who do not die, enormous morbidity, long-term effects on their families, and many hospitalizations are characteristic. The article by Yoon et al1 in this issue of the Archives makes it quite clear that we have a great deal to learn to properly References 1. Yoon PW, Olney RS, Khoury MJ, Sappenfield WM, Chavez GF, Taylor D. Contribution of birth defects and genetic diseases to pediatric hospitalizations: a population-based study . Arch Pediatr Adolesc Med . 1997;151:1096-1103.Crossref 2. Pearce HR. Periconceptual folic acid: knowledge amongst patients and health care workers in a London teaching hospital . Br J Fam Plann . 1996;22:20-21. 3. Forman R, Singal N, Perelman V, et al. Folic acid and prevention of neural tube defects: a study of Canadian mothers of infants with spina bifida . Clin Invest Med . 1996;19:195-201. 4. Knowledge and use of folic acid by women of childbearing age: United States, 1995 . MMWR Morb Mortal Wkly Rep . 1995;44:716-718.

Journal

Archives of Pediatrics & Adolescent MedicineAmerican Medical Association

Published: Nov 1, 1997

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