Abstract In the last few years, many papers of both a basic and clinical nature have been written regarding the effects of light on the skin. It has become necessary to have some understanding of the physical concepts involved in these light reactions. This paper is concerned with the immediate effects of light and will not cover the ultimate biological reactions. Light is absorbed by certain molecules in the skin. In the process, these molecules become excited, are highly reactive, and are capable of entering into reactions. These photochemical reactions can result in the damage of a biologic material such as protein and nucleic acid. References 1. Bachem, A., and Reed, C. I.: Penetration of Light Through Human Skin , Amer J Physiol 97:86-91, 1931. 2. Barrow, G. M.: Structure of Molecules , New York: W. A. Benjamin, Inc., 1963. 3. Giese, A. C.: Photophysiology , New York: Academic Press, Inc., 1964, vol 1 and 2, chap 1-4 , 20. 4. Norins, A. L.: Free Radical Formation in Skin Following Exposure to Ultraviolet Light , J Invest Derm 39:445-447 ( (Nov) ) 1962.Crossref 5. Setlow, R. B., and Pollard, E. C.: Molecular Biophysics , Addison-Wesley Publ. Co., Inc., Reading: 1962, chapt 7 and 9 .
Archives of Dermatology – American Medical Association
Published: Nov 1, 1964