Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

THE HYPOTHALAMIC NUCLEI IN HEAT STROKE: WITH NOTES ON THE CENTRAL REPRESENTATION OF TEMPERATURE REGULATION

THE HYPOTHALAMIC NUCLEI IN HEAT STROKE: WITH NOTES ON THE CENTRAL REPRESENTATION OF TEMPERATURE... Abstract Heat stroke is presumably a condition associated with a breakdown of the mechanisms for control of the body temperature, with resulting loss of power to adjust to an extremely high environmental temperature. In a previous investigation (Morgan1) it was shown that experimental fever produced in the dog and rabbit by injections of typhoid toxin is accompanied by marked chromatolysis in the nucleus tuberomamillaris and by chromatolysis of a lesser and more variable degree in the basal optic ganglia and paraventricular nucleus. Investigations bearing on the role of the hypothalamus in the regulation of body temperature have been reviewed by Fulton2 and in the preceding paper. A study of the diencephalon in patients suffering from heat stroke suggests the following questions: (1) Has the hypothalamus been affected by previous disease or injury, or were the vegetative centers in this region apparently normal prior to the onset of the heat References 1. Morgan, L. O.: Cell Changes in Some of the Hypothalamic Nuclei in Experimental Fever , J. Neurophysiol. 1:281, 1938. 2. Fulton, J. F.: Physiology of the Nervous System , London, Oxford University Press, 1938, p. 246. 3. Morgan, L. O.: The Nuclei of the Region of the Tuber Cinereurn , Arch. Neurol. & Psychiat. 24:267 ( (Aug.) ) 1930. 4. Morgan, L. O., and Gregory, H. S.: Pathological Changes in the Region of the Tuber Cinereum in Idiopathic Epilepsy , Am. J. Psychiat. 9:805, 1930. 5. Morgan, L. O.; Vonderahe, A. R., and Malone, E. F.: Pathological Changes in the Hypothalamus in Diabetes Mellitus , J. Nerv. & Ment. Dis. 85:125, 1937. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology & Psychiatry American Medical Association

THE HYPOTHALAMIC NUCLEI IN HEAT STROKE: WITH NOTES ON THE CENTRAL REPRESENTATION OF TEMPERATURE REGULATION

Loading next page...
 
/lp/american-medical-association/the-hypothalamic-nuclei-in-heat-stroke-with-notes-on-the-central-qQOhkjP9qw
Publisher
American Medical Association
Copyright
Copyright © 1939 American Medical Association. All Rights Reserved.
ISSN
0096-6754
DOI
10.1001/archneurpsyc.1939.02270190091005
Publisher site
See Article on Publisher Site

Abstract

Abstract Heat stroke is presumably a condition associated with a breakdown of the mechanisms for control of the body temperature, with resulting loss of power to adjust to an extremely high environmental temperature. In a previous investigation (Morgan1) it was shown that experimental fever produced in the dog and rabbit by injections of typhoid toxin is accompanied by marked chromatolysis in the nucleus tuberomamillaris and by chromatolysis of a lesser and more variable degree in the basal optic ganglia and paraventricular nucleus. Investigations bearing on the role of the hypothalamus in the regulation of body temperature have been reviewed by Fulton2 and in the preceding paper. A study of the diencephalon in patients suffering from heat stroke suggests the following questions: (1) Has the hypothalamus been affected by previous disease or injury, or were the vegetative centers in this region apparently normal prior to the onset of the heat References 1. Morgan, L. O.: Cell Changes in Some of the Hypothalamic Nuclei in Experimental Fever , J. Neurophysiol. 1:281, 1938. 2. Fulton, J. F.: Physiology of the Nervous System , London, Oxford University Press, 1938, p. 246. 3. Morgan, L. O.: The Nuclei of the Region of the Tuber Cinereurn , Arch. Neurol. & Psychiat. 24:267 ( (Aug.) ) 1930. 4. Morgan, L. O., and Gregory, H. S.: Pathological Changes in the Region of the Tuber Cinereum in Idiopathic Epilepsy , Am. J. Psychiat. 9:805, 1930. 5. Morgan, L. O.; Vonderahe, A. R., and Malone, E. F.: Pathological Changes in the Hypothalamus in Diabetes Mellitus , J. Nerv. & Ment. Dis. 85:125, 1937.

Journal

Archives of Neurology & PsychiatryAmerican Medical Association

Published: Jul 1, 1939

References