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THE GASTRIC MUCOSA OF CHRONIC ALCOHOLIC ADDICTS

THE GASTRIC MUCOSA OF CHRONIC ALCOHOLIC ADDICTS The part that alcohol plays in producing acute gastritis has been known since 1833, when William Beaumont1 first described the "erythema and aphthous patches" and the mucopurulent exudates with blood-tinged red mucus that appeared in St. Martin's stomach after an alcoholic debauch. These observations were confirmed later by Saito,2 who instilled 50 per cent alcohol into the Pavlov pouch of a dog and observed the mucus and the inflammatory changes which resulted. Henning,3 Thomsen4 and Ostrouch5 described the microscopic structural changes which alcohol produced in the gastric epithelium of animals. Ebstein6 produced acute alcoholic gastritis in dogs and observed congestion, edema, hemorrhages and erosions of the mucosa. He found microscopic pathologic changes only in the chief cells of the gastric glands. Faber and Lange7 concluded from their pathologic studies that alcohol is an important factor in producing acute gastritis. That the use of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

THE GASTRIC MUCOSA OF CHRONIC ALCOHOLIC ADDICTS

GRAY, SEYMOUR; SCHINDLER, RUDOLF
JAMA , Volume 117 (12) – Sep 20, 1941
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References (13)

Publisher
American Medical Association
Copyright
Copyright © 1941 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1941.02820380027008
Publisher site
See Article on Publisher Site

Abstract

The part that alcohol plays in producing acute gastritis has been known since 1833, when William Beaumont1 first described the "erythema and aphthous patches" and the mucopurulent exudates with blood-tinged red mucus that appeared in St. Martin's stomach after an alcoholic debauch. These observations were confirmed later by Saito,2 who instilled 50 per cent alcohol into the Pavlov pouch of a dog and observed the mucus and the inflammatory changes which resulted. Henning,3 Thomsen4 and Ostrouch5 described the microscopic structural changes which alcohol produced in the gastric epithelium of animals. Ebstein6 produced acute alcoholic gastritis in dogs and observed congestion, edema, hemorrhages and erosions of the mucosa. He found microscopic pathologic changes only in the chief cells of the gastric glands. Faber and Lange7 concluded from their pathologic studies that alcohol is an important factor in producing acute gastritis. That the use of

Journal

JAMA – American Medical Association

Published: Sep 20, 1941

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