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The Gallium Scan and Inflammatory Lesions

The Gallium Scan and Inflammatory Lesions Abstract It will be ten years since the observation that gallium accumulates in inflammatory lesions.1 The gallium scan has been used to diagnose intra-abdominal abscesses, bone infections, and fevers of unknown origin and to evaluate the extent of inflammatory disease in the lungs (sarcoidosis, tuberculosis, interstitial pneumonitis, and fibrosis). Ebright et al, in this issue (p 246), review the accuracy of the gallium citrate Ga 67 (67Ga) scan. Specificity in the majority of previous studies has been 75% to 96%, with a detection rate of inflammatory lesions (sensitivity) of greater than or equal to 70%. In the current article, the authors draw attention to the frequency of false-positive scans. In the early years of a diagnostic or therapeutic modality, its usefulness can be overestimated. It is possible that the findings by Ebright et al of frequent false-positive scans can be generalized to the current state of the art in 67 References 1. Lavender JP, Lowe J, Barker JR: Gallium-67 citrate scanning in neoplastic and inflammatory lesions. Br J Radiol 1971;44:361-366.Crossref 2. Lisbona R, Cassoff J, Angtuaco E, et al: Comparative accuracy and complementary use of 67Ga-citrate imaging and ultrasound in the diagnosis of abdominal abscesses. Clin Nucl Med 1979;4:108-110.Crossref 3. Kumar B, Anderson PO, Geisse G: The role of Ga-67 citrate imaging and diagnostic ultrasound in patients with suspected abdominal abscesses. J Nucl Med 1977;18:534-537. 4. Filly RA: Detection of abdominal abscesses: A combined approach employing ultrasonography, computed tomography and gallium-67 scanning. J Can Assoc Radiol 1979;30:202-210. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

The Gallium Scan and Inflammatory Lesions

Archives of Internal Medicine , Volume 142 (2) – Feb 1, 1982

The Gallium Scan and Inflammatory Lesions

Abstract

Abstract It will be ten years since the observation that gallium accumulates in inflammatory lesions.1 The gallium scan has been used to diagnose intra-abdominal abscesses, bone infections, and fevers of unknown origin and to evaluate the extent of inflammatory disease in the lungs (sarcoidosis, tuberculosis, interstitial pneumonitis, and fibrosis). Ebright et al, in this issue (p 246), review the accuracy of the gallium citrate Ga 67 (67Ga) scan. Specificity in the majority of previous...
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Publisher
American Medical Association
Copyright
Copyright © 1982 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1982.00340150031004
Publisher site
See Article on Publisher Site

Abstract

Abstract It will be ten years since the observation that gallium accumulates in inflammatory lesions.1 The gallium scan has been used to diagnose intra-abdominal abscesses, bone infections, and fevers of unknown origin and to evaluate the extent of inflammatory disease in the lungs (sarcoidosis, tuberculosis, interstitial pneumonitis, and fibrosis). Ebright et al, in this issue (p 246), review the accuracy of the gallium citrate Ga 67 (67Ga) scan. Specificity in the majority of previous studies has been 75% to 96%, with a detection rate of inflammatory lesions (sensitivity) of greater than or equal to 70%. In the current article, the authors draw attention to the frequency of false-positive scans. In the early years of a diagnostic or therapeutic modality, its usefulness can be overestimated. It is possible that the findings by Ebright et al of frequent false-positive scans can be generalized to the current state of the art in 67 References 1. Lavender JP, Lowe J, Barker JR: Gallium-67 citrate scanning in neoplastic and inflammatory lesions. Br J Radiol 1971;44:361-366.Crossref 2. Lisbona R, Cassoff J, Angtuaco E, et al: Comparative accuracy and complementary use of 67Ga-citrate imaging and ultrasound in the diagnosis of abdominal abscesses. Clin Nucl Med 1979;4:108-110.Crossref 3. Kumar B, Anderson PO, Geisse G: The role of Ga-67 citrate imaging and diagnostic ultrasound in patients with suspected abdominal abscesses. J Nucl Med 1977;18:534-537. 4. Filly RA: Detection of abdominal abscesses: A combined approach employing ultrasonography, computed tomography and gallium-67 scanning. J Can Assoc Radiol 1979;30:202-210.

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Feb 1, 1982

References