Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

THE ETIOLOGY AND PATHOLOGY OF CYSTS OF THE PANCREAS

THE ETIOLOGY AND PATHOLOGY OF CYSTS OF THE PANCREAS Abstract In a previous communication1 we reported on a clinical study of forty-seven cases of pancreatic cysts treated surgically at the Mayo Clinic in the last ten years. In this paper we shall consider: (1) the pathogenesis of cysts of the pancreas, (2) our classification and (3) the pathologic manifestations of such cysts. As a basis for our study, we reviewed the literature, the records at the clinic and the operative and necropsy material obtained in eighty-eight cases of cysts of the pancreas treated surgically, as well as that in twenty cases in which such cysts were discovered incidentally at necropsy. Comparatively little experimental work has been done on the production of cysts in the pancreas. Senn2 ligated the pancreatic duct in dogs but was unable to produce a cyst, although it appeared that ectasia of the duct followed the ligation. He concluded that factors other than mere obstruction References 1. Judd, E. S.; Mattson, Hamlin; and Mahorner, Howard R.: Pancreatic Cysts: Report of Forty-Seven Cases , Arch. Surg. 22:838 ( (May) ) 1931.Crossref 2. Senn, Nicholas: The Surgery of the Pancreas as Based upon Experiments and Clinical Researches , Am. J. M. Sc. 92:141 ( (July) ) 1886Crossref 3. 93:121, 1887 4. Experimental Surgery , Chicago, W. T. Keener, 1889. 5. Oser: Diseases of the Pancreas , in Nothnagel: Encyclopedia , Philadelphia, W. B. Saunders Company, 1903. 6. Lazarus, Paul: Beitrag zur Pathologie und Therapie der Pankreaserkrankungen mit besonderer Berücksichtigung der Cysten und Steine , Ztschr. f. klin. Med. 51:95 and 203, 1904 7. 52:146 and 381, 1904. 8. Binet, Léon; and Brocq, Pierre: Réproduction expérimentale de la pancréatite hémorrhagique avec stéato-nécrose et du pseudo-kyste pancréatique par l'injection de sels de calcium dans le canal de Wirsung , Compt. rend. Soc. de biol. 83:341 ( (March) ) 1920. 9. Opie, E. L.: The Relation of Cholelithiasis to Disease of the Pancreas and to Fat Necrosis , Am. J. M. Sc. 121:27 ( (Jan.) ) 1901Crossref 10. Diseases of the Pancreas , Philadelphia, J. B. Lippincott Company, 1910. 11. Archibald, E.: The Experimental Production of Pancreatitis in Animals as the Result of the Resistance of the Common Duct Sphincter , Surg. Gynec. Obst. 28:529 ( (June) ) 1919. 12. Connolly, D. I.: Note on a Case of Pancreatic Cyst in a Child Aged 14 Months , Lancet 1:803, 1911.Crossref 13. Railton, T. C.: A Case of Pancreatic Cyst in an Infant , Brit. M. J. 2:1318, 1896.Crossref 14. Eha, C. E.: Case of Congenital Pancreatic Cyst , J. A. M. A. 78:1294 ( (April 29) ) 1922. 15. Kaufmann, Eduard: Lehrbuch der speziellen pathologischen Anatomie , Berlin, Walter de Gruyter & Company, 1922 16. Pathology for Students and Practitioners , Philadelphia, P. Blakiston's Son & Company, 1929. 17. Judd, E. S.: Cysts of the Pancreas , Minnesota Med. 4:75 ( (Feb.) ) 1921. 18. Masson, J. C., and Caylor, H. D.: Dermoid Cyst of the Pancreas , Surg. Clin. North America 9:837 ( (Aug.) ) 1929. 19. Dennis, W. A.: Dermoid Cyst of the Pancreas , Surg. Clin. North America 3:1319 ( (Oct.) ) 1923. 20. Carling, E. R., and Hicks, J. A.: A Consideration of Two Cases of Cystadenoma of the Pancreas and Their Probable Relationship to Polycystic Conditions Found in Other Viscera , Brit. J. Surg. 13:238 ( (Oct.) ) 1925.Crossref 21. Lloyd, Jordon; Injury to the Pancreas: A Cause of Effusions into the Lesser Peritoneal Cavity , Brit. M. J. 2:1051, 1892.Crossref 22. Warnock, H. A.: Pseudocyst of the Pancreas , Brit. M. J. 1:104 ( (Jan. 19) ) 1929. 23. Körte, Werner: Die chirurgischen Krankheiten und die Verletzungen des Pankreas , Stuttgart, Ferdinand Enke, 1898. 24. McWhorter, G. L.: Cysts of the Pancreas , Arch. Surg. 11:619 ( (Oct.) ) 1925.Crossref 25. McCann, F. J.: A Large Pancreatic Cyst Simulating an Ovarian Tumor , Proc. Roy. Soc. Med. 4:235, 1912-1913. 26. Carslaw, R. B.: Acute Pancreatitis Followed by Development of a Pancreatic Cyst; Recovery , Lancet 2:132 ( (July 16) ) 1921.Crossref 27. Mayo, W. J.: Pancreatic Cyst , Med. Rec. 45:168 ( (Feb.) ) 1894. 28. Russ, W. B.: Pseudocyst of Pancreas Apparently Due to Hemorrhagic Necrosis Occurring During the Course of a General Sepsis , J. A. M. A. 77:620 ( (Aug. 20) ) 1921.Crossref 29. Virchow, Rudolf: Die krankhaften Geschwülste , Berlin, August Hirschwald, 1863, pp. 276-277. 30. Durante, F.: Cisti da ritenzione del pancreas , Arch. ed atti d. Soc. ital. di chir. 9:109, 1894 31. abstr., Zentralbl. f. Chir. 21:424 ( (April) ) 1894. 32. Münzer, Max: Pankreascysten , Centralbl. f. d. Grenzgeb. d. Med. u. Chir. 6:490, 573 and 664, 1903. 33. Israel, O.: Zwei Fälle von Necrose innere Organe bei Diabetes Mellitus , Virchows Arch. f. path. Anat. 83:181 ( (Jan.) ) 1881.Crossref 34. Tilger, Alfred: Beitrag zur pathologischen Anatomie und Aetiologie der Pancreas-Cysten , Virchows Arch. f. path. Anat. 137:348 ( (July) ) 1894.Crossref 35. Ewing, James: Neoplastic Diseases , Philadelphia, W. B. Saunders Company, 1929. 36. Fitz, R. H.: Multilocular Cystoma of the Pancreas , Am. J. M. Sc. 120:184 ( (Aug.) ) 1900.Crossref 37. Malcolm, J. D.: A Case of Complete Removal of a Multilocular Cystic Tumor of the Pancreas , Lancet 1:1676, 1906.Crossref 38. Scotti, G.: Adeno-Cistoma papillefero del pancréas , Arch. per le sc. med. , 1906 39. abstr., Centralbl. f. allg. Path. u. path. Anat. 18:844 ( (Oct.) ) 1907. 40. Hartman, M.: Kystes du pancréas , Rev. d. chir. 11:409, 1891. 41. Kerr, A. A.: Cysts and Pseudocysts of the Pancreas , Surg. Gynec. Obst. 27:40 ( (July) ) 1918. 42. Hanser, Robert: Ueber Echinokokken des Pankreas , Beitr. z. klin. Chir. 77:360, 1912. 43. Seyfarth, Carly: Parasiten im Pankreas , Centralbl. f. Bakteriol. 85:27 ( (Sept.) ) 1921. 44. Stitt, E. R.: The Diagnostics and Treatment of Tropical Diseases , ed. 5, Philadelphia, P. Blakiston's Son & Company, 1929. 45. Rivas, Damaso: Human Parasitology , Philadelphia, W. B. Saunders Company, 1920. 46. Railliet and Monot: Ascaride dans le pancréas d'un process , Compt. rend. Soc. de biol. 45:407 ( (April) ) 1893. 47. Stapper, Julius: Beiträge zur Diagnose der Pancreascysten , Bonn, Joseph Bach, 1892. 48. Klebs, Edwin: Handbuch der pathologischen Anatomie , ed. 2, Berlin, A. Hirschwald, 1876. 49. Lloyd (footnote 16). Israel (footnote 27). 50. Oser, Leopold: Diseases of the Pancreas , in Nothnagel: Encyclopedia , Philadelphia, W. B. Saunders Company, 1903, pp. 17-270. 51. Pepper, William: Tumour of the Head of the Pancreas , Am. J. M. Sc. 61:159 ( (Oct.) ) 1871.Crossref 52. Lazarus (footnote 4). Körte (footnote 18). 53. Bozeman, N.: Removal of a Cyst of the Pancreas Weighing Twenty and One-Half Pounds , Med. Rec. 21:46 ( (Jan.) ) 1882. 54. Garrigues, H. J.: The Anatomy and Histology of Cyst of the Pancreas , Med. Rec. 21:286 ( (March) ) 1882. 55. Treamaine, W. S.: Cyst of the Pancreas Successfully Removed , Tr. Am. Surg. A. 6:557, 1888. 56. Morton, B. B.: A Case of Pancreatic Cyst Associated with Glycosuria and Gallstones: Necropsy , Lancet 1:242 ( (Jan.) ) 1897. 57. von Jaksch, R.: Ueber das Vorkommen von Fermenten in den Fäces der Kinder, nebst Bermerkungen über das Vorkommen von saccharificierenden Fermenten in Cysteninhalt , Ztschr. f. phys. Chem. 12:116, 1888. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

THE ETIOLOGY AND PATHOLOGY OF CYSTS OF THE PANCREAS

Archives of Surgery , Volume 22 (6) – Jun 1, 1931

Loading next page...
 
/lp/american-medical-association/the-etiology-and-pathology-of-cysts-of-the-pancreas-K74J8rZpvI
Publisher
American Medical Association
Copyright
Copyright © 1931 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1931.01160060146009
Publisher site
See Article on Publisher Site

Abstract

Abstract In a previous communication1 we reported on a clinical study of forty-seven cases of pancreatic cysts treated surgically at the Mayo Clinic in the last ten years. In this paper we shall consider: (1) the pathogenesis of cysts of the pancreas, (2) our classification and (3) the pathologic manifestations of such cysts. As a basis for our study, we reviewed the literature, the records at the clinic and the operative and necropsy material obtained in eighty-eight cases of cysts of the pancreas treated surgically, as well as that in twenty cases in which such cysts were discovered incidentally at necropsy. Comparatively little experimental work has been done on the production of cysts in the pancreas. Senn2 ligated the pancreatic duct in dogs but was unable to produce a cyst, although it appeared that ectasia of the duct followed the ligation. He concluded that factors other than mere obstruction References 1. Judd, E. S.; Mattson, Hamlin; and Mahorner, Howard R.: Pancreatic Cysts: Report of Forty-Seven Cases , Arch. Surg. 22:838 ( (May) ) 1931.Crossref 2. Senn, Nicholas: The Surgery of the Pancreas as Based upon Experiments and Clinical Researches , Am. J. M. Sc. 92:141 ( (July) ) 1886Crossref 3. 93:121, 1887 4. Experimental Surgery , Chicago, W. T. Keener, 1889. 5. Oser: Diseases of the Pancreas , in Nothnagel: Encyclopedia , Philadelphia, W. B. Saunders Company, 1903. 6. Lazarus, Paul: Beitrag zur Pathologie und Therapie der Pankreaserkrankungen mit besonderer Berücksichtigung der Cysten und Steine , Ztschr. f. klin. Med. 51:95 and 203, 1904 7. 52:146 and 381, 1904. 8. Binet, Léon; and Brocq, Pierre: Réproduction expérimentale de la pancréatite hémorrhagique avec stéato-nécrose et du pseudo-kyste pancréatique par l'injection de sels de calcium dans le canal de Wirsung , Compt. rend. Soc. de biol. 83:341 ( (March) ) 1920. 9. Opie, E. L.: The Relation of Cholelithiasis to Disease of the Pancreas and to Fat Necrosis , Am. J. M. Sc. 121:27 ( (Jan.) ) 1901Crossref 10. Diseases of the Pancreas , Philadelphia, J. B. Lippincott Company, 1910. 11. Archibald, E.: The Experimental Production of Pancreatitis in Animals as the Result of the Resistance of the Common Duct Sphincter , Surg. Gynec. Obst. 28:529 ( (June) ) 1919. 12. Connolly, D. I.: Note on a Case of Pancreatic Cyst in a Child Aged 14 Months , Lancet 1:803, 1911.Crossref 13. Railton, T. C.: A Case of Pancreatic Cyst in an Infant , Brit. M. J. 2:1318, 1896.Crossref 14. Eha, C. E.: Case of Congenital Pancreatic Cyst , J. A. M. A. 78:1294 ( (April 29) ) 1922. 15. Kaufmann, Eduard: Lehrbuch der speziellen pathologischen Anatomie , Berlin, Walter de Gruyter & Company, 1922 16. Pathology for Students and Practitioners , Philadelphia, P. Blakiston's Son & Company, 1929. 17. Judd, E. S.: Cysts of the Pancreas , Minnesota Med. 4:75 ( (Feb.) ) 1921. 18. Masson, J. C., and Caylor, H. D.: Dermoid Cyst of the Pancreas , Surg. Clin. North America 9:837 ( (Aug.) ) 1929. 19. Dennis, W. A.: Dermoid Cyst of the Pancreas , Surg. Clin. North America 3:1319 ( (Oct.) ) 1923. 20. Carling, E. R., and Hicks, J. A.: A Consideration of Two Cases of Cystadenoma of the Pancreas and Their Probable Relationship to Polycystic Conditions Found in Other Viscera , Brit. J. Surg. 13:238 ( (Oct.) ) 1925.Crossref 21. Lloyd, Jordon; Injury to the Pancreas: A Cause of Effusions into the Lesser Peritoneal Cavity , Brit. M. J. 2:1051, 1892.Crossref 22. Warnock, H. A.: Pseudocyst of the Pancreas , Brit. M. J. 1:104 ( (Jan. 19) ) 1929. 23. Körte, Werner: Die chirurgischen Krankheiten und die Verletzungen des Pankreas , Stuttgart, Ferdinand Enke, 1898. 24. McWhorter, G. L.: Cysts of the Pancreas , Arch. Surg. 11:619 ( (Oct.) ) 1925.Crossref 25. McCann, F. J.: A Large Pancreatic Cyst Simulating an Ovarian Tumor , Proc. Roy. Soc. Med. 4:235, 1912-1913. 26. Carslaw, R. B.: Acute Pancreatitis Followed by Development of a Pancreatic Cyst; Recovery , Lancet 2:132 ( (July 16) ) 1921.Crossref 27. Mayo, W. J.: Pancreatic Cyst , Med. Rec. 45:168 ( (Feb.) ) 1894. 28. Russ, W. B.: Pseudocyst of Pancreas Apparently Due to Hemorrhagic Necrosis Occurring During the Course of a General Sepsis , J. A. M. A. 77:620 ( (Aug. 20) ) 1921.Crossref 29. Virchow, Rudolf: Die krankhaften Geschwülste , Berlin, August Hirschwald, 1863, pp. 276-277. 30. Durante, F.: Cisti da ritenzione del pancreas , Arch. ed atti d. Soc. ital. di chir. 9:109, 1894 31. abstr., Zentralbl. f. Chir. 21:424 ( (April) ) 1894. 32. Münzer, Max: Pankreascysten , Centralbl. f. d. Grenzgeb. d. Med. u. Chir. 6:490, 573 and 664, 1903. 33. Israel, O.: Zwei Fälle von Necrose innere Organe bei Diabetes Mellitus , Virchows Arch. f. path. Anat. 83:181 ( (Jan.) ) 1881.Crossref 34. Tilger, Alfred: Beitrag zur pathologischen Anatomie und Aetiologie der Pancreas-Cysten , Virchows Arch. f. path. Anat. 137:348 ( (July) ) 1894.Crossref 35. Ewing, James: Neoplastic Diseases , Philadelphia, W. B. Saunders Company, 1929. 36. Fitz, R. H.: Multilocular Cystoma of the Pancreas , Am. J. M. Sc. 120:184 ( (Aug.) ) 1900.Crossref 37. Malcolm, J. D.: A Case of Complete Removal of a Multilocular Cystic Tumor of the Pancreas , Lancet 1:1676, 1906.Crossref 38. Scotti, G.: Adeno-Cistoma papillefero del pancréas , Arch. per le sc. med. , 1906 39. abstr., Centralbl. f. allg. Path. u. path. Anat. 18:844 ( (Oct.) ) 1907. 40. Hartman, M.: Kystes du pancréas , Rev. d. chir. 11:409, 1891. 41. Kerr, A. A.: Cysts and Pseudocysts of the Pancreas , Surg. Gynec. Obst. 27:40 ( (July) ) 1918. 42. Hanser, Robert: Ueber Echinokokken des Pankreas , Beitr. z. klin. Chir. 77:360, 1912. 43. Seyfarth, Carly: Parasiten im Pankreas , Centralbl. f. Bakteriol. 85:27 ( (Sept.) ) 1921. 44. Stitt, E. R.: The Diagnostics and Treatment of Tropical Diseases , ed. 5, Philadelphia, P. Blakiston's Son & Company, 1929. 45. Rivas, Damaso: Human Parasitology , Philadelphia, W. B. Saunders Company, 1920. 46. Railliet and Monot: Ascaride dans le pancréas d'un process , Compt. rend. Soc. de biol. 45:407 ( (April) ) 1893. 47. Stapper, Julius: Beiträge zur Diagnose der Pancreascysten , Bonn, Joseph Bach, 1892. 48. Klebs, Edwin: Handbuch der pathologischen Anatomie , ed. 2, Berlin, A. Hirschwald, 1876. 49. Lloyd (footnote 16). Israel (footnote 27). 50. Oser, Leopold: Diseases of the Pancreas , in Nothnagel: Encyclopedia , Philadelphia, W. B. Saunders Company, 1903, pp. 17-270. 51. Pepper, William: Tumour of the Head of the Pancreas , Am. J. M. Sc. 61:159 ( (Oct.) ) 1871.Crossref 52. Lazarus (footnote 4). Körte (footnote 18). 53. Bozeman, N.: Removal of a Cyst of the Pancreas Weighing Twenty and One-Half Pounds , Med. Rec. 21:46 ( (Jan.) ) 1882. 54. Garrigues, H. J.: The Anatomy and Histology of Cyst of the Pancreas , Med. Rec. 21:286 ( (March) ) 1882. 55. Treamaine, W. S.: Cyst of the Pancreas Successfully Removed , Tr. Am. Surg. A. 6:557, 1888. 56. Morton, B. B.: A Case of Pancreatic Cyst Associated with Glycosuria and Gallstones: Necropsy , Lancet 1:242 ( (Jan.) ) 1897. 57. von Jaksch, R.: Ueber das Vorkommen von Fermenten in den Fäces der Kinder, nebst Bermerkungen über das Vorkommen von saccharificierenden Fermenten in Cysteninhalt , Ztschr. f. phys. Chem. 12:116, 1888.

Journal

Archives of SurgeryAmerican Medical Association

Published: Jun 1, 1931

References