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The Etiology and Natural History of Sinus Node Disorders

The Etiology and Natural History of Sinus Node Disorders Abstract • Two aspects of sinus node disorders currently seem to need emphasis—the etiology, which is still a difficult area, and the detailed structuring of the natural history of the sick sinus syndrome (SSS). The latter is becoming much clearer. The multifaceted influences of normal S-A nodal functions are reviewed. Degenerative fibrosis is the commonest abnormality, and coronary artery disease is not a major cause of the syndrome. The framework of the progressive natural history of the SSS in its usual sequential phases can now be constructed. Of course, not every feature of this progression is perceived in each patient. Gradually developing stages are reviewed, new data concerning behavior of rescue rhythms in S-A node disorders are presented, and a brief comment concerning the needs for and complications of pacing is included. (Arch Intern Med 1982;142:371-372) References 1. Ferrer MI: The sick sinus syndrome in atrial disease. JAMA 1968;206:645-646.Crossref 2. Shaw DB, Kekwick CA: Potential candidates for pacemakers: Survey of heart block and sinoatrial disorder (sick sinus syndrome). Br Heart J 1978;40:99-105.Crossref 3. Ferrer MI: The primary pacemaker: Functions, falterings, fate and false alarms. Chest 1979;75:376-379.Crossref 4. Jordan J, Yamaguchi I, Mandel WJ, et al: Comparative effects of overdrive on sinus and subsidiary pacemaker function. Am Heart J 1977;93:367-374.Crossref 5. Loeb JM, Euler DE, Randall WC, et al: Cardiac arrhythmias after chronic embolization of the sinus node artery: Alterations in parasympathetic control. Circulation 1980;61:192-198.Crossref 6. Ferrer MI: Rescue rhythms in the sick sinus syndrome: With special reference to slow atrial rhythm. Cardiovasc Rev Reports 1981;2:149-152. 7. Gomez JAC, Kang PS, Matheson M, et al: Coexistence of sick sinus rhythm and atrial flutter-fibrillation. Circulation 1981;63:80.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

The Etiology and Natural History of Sinus Node Disorders

Archives of Internal Medicine , Volume 142 (2) – Feb 1, 1982

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Publisher
American Medical Association
Copyright
Copyright © 1982 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1982.00340150171028
Publisher site
See Article on Publisher Site

Abstract

Abstract • Two aspects of sinus node disorders currently seem to need emphasis—the etiology, which is still a difficult area, and the detailed structuring of the natural history of the sick sinus syndrome (SSS). The latter is becoming much clearer. The multifaceted influences of normal S-A nodal functions are reviewed. Degenerative fibrosis is the commonest abnormality, and coronary artery disease is not a major cause of the syndrome. The framework of the progressive natural history of the SSS in its usual sequential phases can now be constructed. Of course, not every feature of this progression is perceived in each patient. Gradually developing stages are reviewed, new data concerning behavior of rescue rhythms in S-A node disorders are presented, and a brief comment concerning the needs for and complications of pacing is included. (Arch Intern Med 1982;142:371-372) References 1. Ferrer MI: The sick sinus syndrome in atrial disease. JAMA 1968;206:645-646.Crossref 2. Shaw DB, Kekwick CA: Potential candidates for pacemakers: Survey of heart block and sinoatrial disorder (sick sinus syndrome). Br Heart J 1978;40:99-105.Crossref 3. Ferrer MI: The primary pacemaker: Functions, falterings, fate and false alarms. Chest 1979;75:376-379.Crossref 4. Jordan J, Yamaguchi I, Mandel WJ, et al: Comparative effects of overdrive on sinus and subsidiary pacemaker function. Am Heart J 1977;93:367-374.Crossref 5. Loeb JM, Euler DE, Randall WC, et al: Cardiac arrhythmias after chronic embolization of the sinus node artery: Alterations in parasympathetic control. Circulation 1980;61:192-198.Crossref 6. Ferrer MI: Rescue rhythms in the sick sinus syndrome: With special reference to slow atrial rhythm. Cardiovasc Rev Reports 1981;2:149-152. 7. Gomez JAC, Kang PS, Matheson M, et al: Coexistence of sick sinus rhythm and atrial flutter-fibrillation. Circulation 1981;63:80.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Feb 1, 1982

References