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The Effect of Air Embolism on Renal Preservation

The Effect of Air Embolism on Renal Preservation Abstract • Air embolism to the kidneys was induced in dogs during an ex vivo perfusion preservation period using cryoprecipitated plasma to demonstrate the effect of air embolism on the function of the preserved kidneys. A sharp decline in plasma flow rate was observed after air was infused, but the rate returned to the preembolism range in 60 minutes. Differences in posttransplant serum creatinine levels between the control and air embolism groups were not statistically significant. No deleterious effect was demonstrated on the final function of preserved kidneys by infusion of air. Three cadaver kidneys that accidentally sustained air embolism during the perfusion preservation period were transplanted. Although an initial period of acute tubular necrosis developed in these three kidneys, two kidneys regained good renal function and the third kidney was removed because of irreversible rejection. This study demonstrates that kidneys that sustain air embolism can be used for clinical transplantation. (Arch Surg 111:271-272, 1976) References 1. Cho SI, Der Hagopian RP, Krane RS, et al: Regional organ preservation program in the New England area . Surgery 75:528-534, 1974. 2. Belzer FO, Kountz SL: Preservation and transplantation of human cadaver kidneys: A two-year experience . Ann Surg 172:394-404, 1970.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

The Effect of Air Embolism on Renal Preservation

Archives of Surgery , Volume 111 (3) – Mar 1, 1976

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Publisher
American Medical Association
Copyright
Copyright © 1976 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1976.01360210065012
Publisher site
See Article on Publisher Site

Abstract

Abstract • Air embolism to the kidneys was induced in dogs during an ex vivo perfusion preservation period using cryoprecipitated plasma to demonstrate the effect of air embolism on the function of the preserved kidneys. A sharp decline in plasma flow rate was observed after air was infused, but the rate returned to the preembolism range in 60 minutes. Differences in posttransplant serum creatinine levels between the control and air embolism groups were not statistically significant. No deleterious effect was demonstrated on the final function of preserved kidneys by infusion of air. Three cadaver kidneys that accidentally sustained air embolism during the perfusion preservation period were transplanted. Although an initial period of acute tubular necrosis developed in these three kidneys, two kidneys regained good renal function and the third kidney was removed because of irreversible rejection. This study demonstrates that kidneys that sustain air embolism can be used for clinical transplantation. (Arch Surg 111:271-272, 1976) References 1. Cho SI, Der Hagopian RP, Krane RS, et al: Regional organ preservation program in the New England area . Surgery 75:528-534, 1974. 2. Belzer FO, Kountz SL: Preservation and transplantation of human cadaver kidneys: A two-year experience . Ann Surg 172:394-404, 1970.Crossref

Journal

Archives of SurgeryAmerican Medical Association

Published: Mar 1, 1976

References