CLINICAL SCIENCES The Detection of Motion by Blind Subjects With the Epiretinal 60-Electrode (Argus II) Retinal Prosthesis Jessy D. Dorn, PhD; Ashish K. Ahuja, PhD; Avi Caspi, PhD; Lyndon da Cruz, MD; Gislin Dagnelie, PhD; Jose-Alain Sahel, MD; Robert J. Greenberg, MD, PhD; Matthew J. McMahon, PhD; for the Argus II Study Group Objective: To investigate the ability of 28 blind sub- and no difference was found for 11 subjects. Of the 15 jects implanted with a 60-electrode Argus II (Second Sight better-performing subjects, 11 were available for fol- Medical Products Inc) retinal prosthesis system to de- low-up testing, and 10 of them had significantly better tect the direction of a moving object. performance with normal rather than with scrambled spa- tial information. Methods: Blind subjects (bare light perception or worse in both eyes) with retinitis pigmentosa were implanted Conclusions: This work demonstrates that blind sub- with the Argus II prosthesis as part of a phase 1/2 feasi- jects implanted with the Argus II retinal prosthesis were bility study at multiple clinical sites worldwide. The ex- able to perform a motion detection task they could not periment measured their ability to detect the direction do with their native vision,
JAMA Ophthalmology – American Medical Association
Published: Feb 1, 2013
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