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The Complications of Corticosteroids

The Complications of Corticosteroids Systemic administration of antibiotics prior to surgery in patients who have been on corticosteroid therapy may significantly reduce the incidence of deep infections, a surgeon from Yale University reports. Infection has been known to be a common complication of longterm steroid therapy due in part to the inhibition of antibody formation. Generally, physicians have begun antibiotic therapy after surgery when infection is evident. Mark A. Hayes, MD, has shown, however, that the infection process may be initiated in the lymph nodes of such patients prior to surgery. His studies suggest that antibiotic therapy is more effective if started before surgery and continued during and after surgery. The management program he uses has not resulted in any postoperative deep infections in a series of 42 patients. Dr. Hayes, a member of a panel on the complications of corticosteroid therapy at a meeting of the American College of Surgeons, Bal Harbour, Fla, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

The Complications of Corticosteroids

JAMA , Volume 195 (6) – Feb 7, 1966

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Publisher
American Medical Association
Copyright
Copyright © 1966 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1966.03100060018008
Publisher site
See Article on Publisher Site

Abstract

Systemic administration of antibiotics prior to surgery in patients who have been on corticosteroid therapy may significantly reduce the incidence of deep infections, a surgeon from Yale University reports. Infection has been known to be a common complication of longterm steroid therapy due in part to the inhibition of antibody formation. Generally, physicians have begun antibiotic therapy after surgery when infection is evident. Mark A. Hayes, MD, has shown, however, that the infection process may be initiated in the lymph nodes of such patients prior to surgery. His studies suggest that antibiotic therapy is more effective if started before surgery and continued during and after surgery. The management program he uses has not resulted in any postoperative deep infections in a series of 42 patients. Dr. Hayes, a member of a panel on the complications of corticosteroid therapy at a meeting of the American College of Surgeons, Bal Harbour, Fla,

Journal

JAMAAmerican Medical Association

Published: Feb 7, 1966

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