Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

The CNS in Guillain-Barré Syndrome

The CNS in Guillain-Barré Syndrome Abstract To the Editor. —We read with interest the article on eye movement disorders in Fisher's syndrome by Meienberg and Ryffel1 and the editorial on the CNS in Guillain-Barré syndrome by Ropper.2We agree with the conclusions expressed by the former authors that the oculomotor abnormalities found in cases of Fisher's syndrome can be explained by a central mechanism at least as well as by a peripheral one, and that the two mechanisms are not mutually exclusive. Ropper's view that the peripheral hypothesis provides the answer in all cases is extreme and misinterprets available evidence. Few could take issue with his statement that there is an "absence of primary pathologic change in the brain stems of persons with Guillain-Barré syndrome," but this cannot be instantly extrapolated to include Fisher's syndrome. In our own series of patient with brain-stem encephalitis,3 all 18 patients had ophthalmoplegia and ataxia, and ten References 1. Meienberg O, Ryffel E: Supranuclear eye movement disorders in Fisher's syndrome of ophthalmoplegia, ataxia, and areflexia: Report of a case and literature review . Arch Neurol 1983; 40:402-405.Crossref 2. Ropper AH: The CNS in Guillain-Barré syndrome . Arch Neurol 1983;40:397-398.Crossref 3. Al-din AN, Anderson M, Bickerstaff ER, et al: Brainstem encephalitis and the syndrome of Miller Fisher: A clinical study . Brain 1982; 105:481-495.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

The CNS in Guillain-Barré Syndrome

Abstract

Abstract To the Editor. —We read with interest the article on eye movement disorders in Fisher's syndrome by Meienberg and Ryffel1 and the editorial on the CNS in Guillain-Barré syndrome by Ropper.2We agree with the conclusions expressed by the former authors that the oculomotor abnormalities found in cases of Fisher's syndrome can be explained by a central mechanism at least as well as by a peripheral one, and that the two mechanisms are not mutually exclusive....
Loading next page...
 
/lp/american-medical-association/the-cns-in-guillain-barr-syndrome-HTe6zNojmV
Publisher
American Medical Association
Copyright
Copyright © 1984 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1984.04050180027009
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor. —We read with interest the article on eye movement disorders in Fisher's syndrome by Meienberg and Ryffel1 and the editorial on the CNS in Guillain-Barré syndrome by Ropper.2We agree with the conclusions expressed by the former authors that the oculomotor abnormalities found in cases of Fisher's syndrome can be explained by a central mechanism at least as well as by a peripheral one, and that the two mechanisms are not mutually exclusive. Ropper's view that the peripheral hypothesis provides the answer in all cases is extreme and misinterprets available evidence. Few could take issue with his statement that there is an "absence of primary pathologic change in the brain stems of persons with Guillain-Barré syndrome," but this cannot be instantly extrapolated to include Fisher's syndrome. In our own series of patient with brain-stem encephalitis,3 all 18 patients had ophthalmoplegia and ataxia, and ten References 1. Meienberg O, Ryffel E: Supranuclear eye movement disorders in Fisher's syndrome of ophthalmoplegia, ataxia, and areflexia: Report of a case and literature review . Arch Neurol 1983; 40:402-405.Crossref 2. Ropper AH: The CNS in Guillain-Barré syndrome . Arch Neurol 1983;40:397-398.Crossref 3. Al-din AN, Anderson M, Bickerstaff ER, et al: Brainstem encephalitis and the syndrome of Miller Fisher: A clinical study . Brain 1982; 105:481-495.Crossref

Journal

Archives of NeurologyAmerican Medical Association

Published: Jul 1, 1984

References