Abstract A comparative study of 105 patients with borderline serum fluorescent treponemal antibody absorption (FTA-ABS) test results and 50 patients with nonreactive serum FTA-ABS test results was performed. "Syphilitic pupils" were found in 4% of the patients with nonreactive FTA-ABS tests, but in 15% of the borderline group. Optic atrophy was found in 18% of the control group and in 29% of the borderline group. Optic neuritis was present in 2% of the control group, and in 9.5% of the borderline group. The report of a ± nonreactive or borderline FTA-ABS test is significant to the clinician. Not only should the test be repeated, but a careful history should be taken and a complete examination for subtle signs of late ocular and neurosyphilis should be performed. References 1. Harner RE, Smith JL, Israel CW: The FTA-ABS test in late syphilis . JAMA 203:545, 1968.Crossref 2. Diem K (ed): Scientific tables , in Documenta Geigy , ed 6. Ardsley, NY, Geigy, 1968. 3. Cohen P, Stout G, Ende N: Serologic reactivity in consecutive patients admitted to a general hospital . Arch Intern Med 124:364, 1969.Crossref 4. Smith JL: Spirochetes in Late Seronegative Syphilis, Penicillin Notwithstanding . Springfield, Ill, Charles C Thomas Publisher, 1969, p 331.
Archives of Ophthalmology – American Medical Association
Published: Jan 1, 1972
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