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THE BODY BUILD ASPECT OF IMMUNITY TO DIPHTHERIA

THE BODY BUILD ASPECT OF IMMUNITY TO DIPHTHERIA The anthropometric studies that have been made in various diseases, such as tuberculosis,1 allergy and poliomyelitis,2 may be considered an indirect approach toward correlating body build with susceptibility and resistance to disease. However, not until there was some means of measuring an immune substance could immunity be subjected to anthropometric studies and the results of these studies, in turn, correlated with body build. The diphtheria antitoxin in human serum is at present the only readily measurable immune substance. The antitoxin does not occur in measurable amounts in the blood of most children unless, or until, its production is stimulated by administration of diphtheria toxin or toxoid. A study of the antitoxin response to such stimulation has been previously reported in one cross section of the child population.3 The diphtheria antitoxin content of the blood serum was determined by the method of Jensen.4 The distribution of the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

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References (2)

Publisher
American Medical Association
Copyright
Copyright © 1941 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1941.02000080066009
Publisher site
See Article on Publisher Site

Abstract

The anthropometric studies that have been made in various diseases, such as tuberculosis,1 allergy and poliomyelitis,2 may be considered an indirect approach toward correlating body build with susceptibility and resistance to disease. However, not until there was some means of measuring an immune substance could immunity be subjected to anthropometric studies and the results of these studies, in turn, correlated with body build. The diphtheria antitoxin in human serum is at present the only readily measurable immune substance. The antitoxin does not occur in measurable amounts in the blood of most children unless, or until, its production is stimulated by administration of diphtheria toxin or toxoid. A study of the antitoxin response to such stimulation has been previously reported in one cross section of the child population.3 The diphtheria antitoxin content of the blood serum was determined by the method of Jensen.4 The distribution of the

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Feb 1, 1941

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