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THE BENEFICIAL EFFECTS OF BARIUM CHLORID ON ADAMS-STOKES DISEASE: REPORT OF THREE CASES

THE BENEFICIAL EFFECTS OF BARIUM CHLORID ON ADAMS-STOKES DISEASE: REPORT OF THREE CASES Abstract It frequently happens in the course of complete heart block that attacks of syncope appear associated with standstill of the ventricles. These are the classical attacks known as the Adams-Stokes syndrome. It appears to be a fact that the severity of the attacks depends on the duration of the ventricular asystole. It has been reported1 that the subcutaneous injection of epinephrin can do away with such attacks, but as the effect of epinephrin generally lasts a very short time, it does not seem likely that the recurrence of attacks is thus prevented. Epinephrin failed to prevent the reappearance of syncope in one of the cases reported here. However, no method has been proposed so far for dealing directly with these attacks in the sense of diminishing their frequency or preventing them. This has been accomplished in the following three cases by the oral administration of barium chlorid. The periods of References 1. Phear, A. G., and Parkinson, J.: Adrenalin in the Stokes-Adams Syndrome , Lancet 1:933 ( (May 13) ) 1922.Crossref 2. Rothberger, C. J., and Winterberg, H.: Ueber die experimentelle Erzeugung extrasystolischer ventrikulärer Tachycardie durch Accelerausreizung , Arch. f. d. ges. Physiol. 142:461, 1911.Crossref 3. Van Egmond, A. A. J.: Ueber die Wirkung einiger Arzneimittel beim vollständigen Herzblock , Arch. f. d. ges. Physiol. 154:39, 1913.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

THE BENEFICIAL EFFECTS OF BARIUM CHLORID ON ADAMS-STOKES DISEASE: REPORT OF THREE CASES

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Publisher
American Medical Association
Copyright
Copyright © 1925 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1925.00120130004001
Publisher site
See Article on Publisher Site

Abstract

Abstract It frequently happens in the course of complete heart block that attacks of syncope appear associated with standstill of the ventricles. These are the classical attacks known as the Adams-Stokes syndrome. It appears to be a fact that the severity of the attacks depends on the duration of the ventricular asystole. It has been reported1 that the subcutaneous injection of epinephrin can do away with such attacks, but as the effect of epinephrin generally lasts a very short time, it does not seem likely that the recurrence of attacks is thus prevented. Epinephrin failed to prevent the reappearance of syncope in one of the cases reported here. However, no method has been proposed so far for dealing directly with these attacks in the sense of diminishing their frequency or preventing them. This has been accomplished in the following three cases by the oral administration of barium chlorid. The periods of References 1. Phear, A. G., and Parkinson, J.: Adrenalin in the Stokes-Adams Syndrome , Lancet 1:933 ( (May 13) ) 1922.Crossref 2. Rothberger, C. J., and Winterberg, H.: Ueber die experimentelle Erzeugung extrasystolischer ventrikulärer Tachycardie durch Accelerausreizung , Arch. f. d. ges. Physiol. 142:461, 1911.Crossref 3. Van Egmond, A. A. J.: Ueber die Wirkung einiger Arzneimittel beim vollständigen Herzblock , Arch. f. d. ges. Physiol. 154:39, 1913.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Jul 1, 1925

References