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The Antigonadotropic Factor, with Consideration of the Antihormone Problem.

The Antigonadotropic Factor, with Consideration of the Antihormone Problem. This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In this monograph Zondek and Sulman present a rather full discussion of the problem of the antigonadotropic problem. They not only include a review of the literature but describe a few unpublished observations of their own. The data are divided and discussed as follows: "Historical Review," "The Antihormone Theory of Collip," "The Antigonadotropic Factor," "Clinical Significance of the 'Antihormones' " and "Mechanism of the Antigonadotropic Reaction." The authors present evidence which they believe strongly indicates that the antigonadotropic substances are to be classified "as a group of immune bodies of a character hitherto unknown in serology." The monograph should be of great interest not only to persons interested in endocrinology, but to physiologists, biochemists, immunologists and internists. It tends to emphasize the immunologic mechanisms of antigonadotropic activity instead of the point of view that an antagonistic hormone is secreted that neutralizes gonadotropic substances. Many aspects of this problem, obviously, will remain http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

The Antigonadotropic Factor, with Consideration of the Antihormone Problem.

Archives of Internal Medicine , Volume 71 (4) – Apr 1, 1943

The Antigonadotropic Factor, with Consideration of the Antihormone Problem.

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In this monograph Zondek and Sulman present a rather full discussion of the problem of the antigonadotropic problem. They not only include a review of the literature but describe a few unpublished observations of their own. The data are divided and discussed as follows: "Historical Review," "The Antihormone Theory of Collip,"...
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Publisher
American Medical Association
Copyright
Copyright © 1943 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1943.00210040141018
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In this monograph Zondek and Sulman present a rather full discussion of the problem of the antigonadotropic problem. They not only include a review of the literature but describe a few unpublished observations of their own. The data are divided and discussed as follows: "Historical Review," "The Antihormone Theory of Collip," "The Antigonadotropic Factor," "Clinical Significance of the 'Antihormones' " and "Mechanism of the Antigonadotropic Reaction." The authors present evidence which they believe strongly indicates that the antigonadotropic substances are to be classified "as a group of immune bodies of a character hitherto unknown in serology." The monograph should be of great interest not only to persons interested in endocrinology, but to physiologists, biochemists, immunologists and internists. It tends to emphasize the immunologic mechanisms of antigonadotropic activity instead of the point of view that an antagonistic hormone is secreted that neutralizes gonadotropic substances. Many aspects of this problem, obviously, will remain

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Apr 1, 1943

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