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The Aging Effect on Intraocular Pressure in an Apparently Normal Population

The Aging Effect on Intraocular Pressure in an Apparently Normal Population Abstract • Statistical analysis of intraocular pressure was conducted on approximately 200,000 healthy subjects who were examined at the Aichi Prefectural Center of Health Care in Nagoya, Japan, during the last decade. The IOP was estimated with either Schiøtz or noncontact tonometers, which consistently showed a decreasing tendency of IOP with age in both sexes. Multivariate analysis on systemic values disclosed that obesity, systolic BP, and age were the most influential factors of IOP. Stratification of the sample by systolic BP, obesity index, and age indicated that young, obese, and hypertensive subjects had the highest IOP, while old, lean, and hypotensive subjects showed the lowest IOP. It was confirmed that the IOP is physiologically maintained by a counterbalance between the IOP-lowering effect of age and the IOP-raising effects of obesity and systolic hypertension, which are largely age dependent. References 1. Leydhecker W, Akiyama K, Neumann HG: Der intraoculare Druck gesunder menschlicher Augen . Klin Monatsbl Augenheilkd 1958;133:662-670. 2. Armaly MF: On the distribution of applanation pressure: I. Statistical features and effect of age, sex, and family history of glaucoma . Arch Ophthalmol 1965;73:11-18.Crossref 3. Armaly MF: Age and sex correction of applanation pressure . Arch Ophthalmol 1967; 78:480-484.Crossref 4. Hollowes FC, Graham PA: Intraocular pressure, glaucoma, and glaucoma suspects in a defined population . Br J Ophthalmol 1966;50:570-586.Crossref 5. Shiose Y, Kawase Y, Sato T, et al: Multivariate analysis on normal ocular tensions . Jpn J Clin Ophthalmol 1981;35:197-206. 6. Suda K, Kiridohshi Y: Frequency distribution of normal ocular tension . Acta Jpn Ophthalmol 1953;57:886-891. 7. Hoshizumi K: Interrelation between ocular tension and systemic blood pressure: I. Ocular tension in normals . Acta Jpn Ophthalmol 1957; 61:661-667. 8. Kurokawa M: Studies on the normal intraocular pressure . Acta Jpn Ophthalmol 1969; 73:112-122. 9. Bengtsson B: Some factors affecting the relationship between Schiøtz and Goldmann readings in a population . Acta Ophthalmol 1973; 51:798-810.Crossref 10. Bulpit CJ, Hodes C, Everitt MG: Intraocular pressure and systemic blood pressure in the elderly . Br J Ophthalmol 1975;59:717-720.Crossref 11. Kahn HA, Leibowitz HM, Ganley JP, et al: The Framingham Eye Study: II. Association of ophthalmic pathology with single variables previously measured in the Framingham Heart Study . Epidemiol Rev 1977;106:33-41. 12. Klein BE, Klein R: Intraocular pressure and cardiovascular risk variables . Arch Ophthalmol 1981;99:837-839.Crossref 13. Williams RH, Glomset JA: Lipid metabolism and eipopathies , in Williams RH (ed): Textbook of Endocrinology , ed 4. Philadelphia, WB Saunders Co, 1969, chap 14. 14. Matsuki S, Suzuki A: Definition, judgement and epidemiology of obesity . Clin Adult Dis 1979;9:919-923. 15. National Health Survey, Blood Pressure of Adults by Age and Sex, United States, 1960-1962 . Vital and Health Statistics Series II, No. 4. US Dept of Health, Education, and Welfare, Public Health Service, 1964, pp 1-40. 16. Kass MA, Zimmermann TJ, Alton E, et al: Intraocular pressure and glaucoma in the Zuni Indians . Arch Ophthalmol 1978;96:2212-2213.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

The Aging Effect on Intraocular Pressure in an Apparently Normal Population

Archives of Ophthalmology , Volume 102 (6) – Jun 1, 1984

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Publisher
American Medical Association
Copyright
Copyright © 1984 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1984.01040030703023
Publisher site
See Article on Publisher Site

Abstract

Abstract • Statistical analysis of intraocular pressure was conducted on approximately 200,000 healthy subjects who were examined at the Aichi Prefectural Center of Health Care in Nagoya, Japan, during the last decade. The IOP was estimated with either Schiøtz or noncontact tonometers, which consistently showed a decreasing tendency of IOP with age in both sexes. Multivariate analysis on systemic values disclosed that obesity, systolic BP, and age were the most influential factors of IOP. Stratification of the sample by systolic BP, obesity index, and age indicated that young, obese, and hypertensive subjects had the highest IOP, while old, lean, and hypotensive subjects showed the lowest IOP. It was confirmed that the IOP is physiologically maintained by a counterbalance between the IOP-lowering effect of age and the IOP-raising effects of obesity and systolic hypertension, which are largely age dependent. References 1. Leydhecker W, Akiyama K, Neumann HG: Der intraoculare Druck gesunder menschlicher Augen . Klin Monatsbl Augenheilkd 1958;133:662-670. 2. Armaly MF: On the distribution of applanation pressure: I. Statistical features and effect of age, sex, and family history of glaucoma . Arch Ophthalmol 1965;73:11-18.Crossref 3. Armaly MF: Age and sex correction of applanation pressure . Arch Ophthalmol 1967; 78:480-484.Crossref 4. Hollowes FC, Graham PA: Intraocular pressure, glaucoma, and glaucoma suspects in a defined population . Br J Ophthalmol 1966;50:570-586.Crossref 5. Shiose Y, Kawase Y, Sato T, et al: Multivariate analysis on normal ocular tensions . Jpn J Clin Ophthalmol 1981;35:197-206. 6. Suda K, Kiridohshi Y: Frequency distribution of normal ocular tension . Acta Jpn Ophthalmol 1953;57:886-891. 7. Hoshizumi K: Interrelation between ocular tension and systemic blood pressure: I. Ocular tension in normals . Acta Jpn Ophthalmol 1957; 61:661-667. 8. Kurokawa M: Studies on the normal intraocular pressure . Acta Jpn Ophthalmol 1969; 73:112-122. 9. Bengtsson B: Some factors affecting the relationship between Schiøtz and Goldmann readings in a population . Acta Ophthalmol 1973; 51:798-810.Crossref 10. Bulpit CJ, Hodes C, Everitt MG: Intraocular pressure and systemic blood pressure in the elderly . Br J Ophthalmol 1975;59:717-720.Crossref 11. Kahn HA, Leibowitz HM, Ganley JP, et al: The Framingham Eye Study: II. Association of ophthalmic pathology with single variables previously measured in the Framingham Heart Study . Epidemiol Rev 1977;106:33-41. 12. Klein BE, Klein R: Intraocular pressure and cardiovascular risk variables . Arch Ophthalmol 1981;99:837-839.Crossref 13. Williams RH, Glomset JA: Lipid metabolism and eipopathies , in Williams RH (ed): Textbook of Endocrinology , ed 4. Philadelphia, WB Saunders Co, 1969, chap 14. 14. Matsuki S, Suzuki A: Definition, judgement and epidemiology of obesity . Clin Adult Dis 1979;9:919-923. 15. National Health Survey, Blood Pressure of Adults by Age and Sex, United States, 1960-1962 . Vital and Health Statistics Series II, No. 4. US Dept of Health, Education, and Welfare, Public Health Service, 1964, pp 1-40. 16. Kass MA, Zimmermann TJ, Alton E, et al: Intraocular pressure and glaucoma in the Zuni Indians . Arch Ophthalmol 1978;96:2212-2213.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Jun 1, 1984

References