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THE ADMINISTRATION OF EGG WHITE AND AVIDIN CONCENTRATES TO PATIENTS WITH CANCER

THE ADMINISTRATION OF EGG WHITE AND AVIDIN CONCENTRATES TO PATIENTS WITH CANCER A rational basis for the treatment of cancer is to deprive the neoplastic tissue of the components required for its growth. This basis presumes that neoplastic cells either contain certain constituents lacked by their normal analogues or that the requirement for those constituents by the cancer tissue is greater than that of normal tissue. Recently, several types of carcinoma were reported to contain abnormally high concentrations of biotin.1 About the same time it was noted that the addition of biotin to diets which prevented in rats the development of hepatomas induced by the feeding of butter yellow broke down the protection those diets otherwise afforded.2 These observations do not necessarily imply that biotin is required for the induction or growth of neoplastic tissue. They do suggest the possibility however that, if biotin should be withheld from patients bearing cancer, the growth of the neoplasm might be decreased to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

THE ADMINISTRATION OF EGG WHITE AND AVIDIN CONCENTRATES TO PATIENTS WITH CANCER

JAMA , Volume 121 (16) – Apr 17, 1943

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References (5)

Publisher
American Medical Association
Copyright
Copyright © 1943 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1943.02840160011003
Publisher site
See Article on Publisher Site

Abstract

A rational basis for the treatment of cancer is to deprive the neoplastic tissue of the components required for its growth. This basis presumes that neoplastic cells either contain certain constituents lacked by their normal analogues or that the requirement for those constituents by the cancer tissue is greater than that of normal tissue. Recently, several types of carcinoma were reported to contain abnormally high concentrations of biotin.1 About the same time it was noted that the addition of biotin to diets which prevented in rats the development of hepatomas induced by the feeding of butter yellow broke down the protection those diets otherwise afforded.2 These observations do not necessarily imply that biotin is required for the induction or growth of neoplastic tissue. They do suggest the possibility however that, if biotin should be withheld from patients bearing cancer, the growth of the neoplasm might be decreased to

Journal

JAMAAmerican Medical Association

Published: Apr 17, 1943

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