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The Acute Respiratory Distress Syndrome

The Acute Respiratory Distress Syndrome Editorials represent the opinions EDITORIAL of the authors and JAMA and not those of the American Medical Association. What’s in a Name? dence and mortality rates ranging between 10% and 90%. Derek C. Angus, MD, MPH In response to these widely varying estimates, the Ameri- can Thoracic Society (ATS) and the European Society of In- EFINING A SYNDROME OR DISEASE IN THE ABSENCE tensive Care Medicine (ESICM), with support from the Na- of unambiguous clinical and pathological find- tional Heart, Lung, and Blood Institute (NHLBI), convened ings is a vexing yet essential challenge in medi- a task force of experts in ARDS to develop a common defi- Dcine. Any proposed definition will be somewhat nition. After 2 meetings, the committee published the first arbitrary and open to dispute. However, failure to agree on American-European Consensus Conference (AECC) crite- a definition will leave clinicians and researchers rudder- ria for ARDS and related syndromes in 1994. less. Without a unified definition of a disease, it is difficult The AECC definition had 4 key components. First, the to conduct epidemiologic studies, to assess the benefits and syndrome must present acutely. Second, there must be harms of potential therapies, and ultimately to care http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

The Acute Respiratory Distress Syndrome

JAMA , Volume 307 (23) – Jun 20, 2012

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Publisher
American Medical Association
Copyright
Copyright 2012 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2012.6761
pmid
22797455
Publisher site
See Article on Publisher Site

Abstract

Editorials represent the opinions EDITORIAL of the authors and JAMA and not those of the American Medical Association. What’s in a Name? dence and mortality rates ranging between 10% and 90%. Derek C. Angus, MD, MPH In response to these widely varying estimates, the Ameri- can Thoracic Society (ATS) and the European Society of In- EFINING A SYNDROME OR DISEASE IN THE ABSENCE tensive Care Medicine (ESICM), with support from the Na- of unambiguous clinical and pathological find- tional Heart, Lung, and Blood Institute (NHLBI), convened ings is a vexing yet essential challenge in medi- a task force of experts in ARDS to develop a common defi- Dcine. Any proposed definition will be somewhat nition. After 2 meetings, the committee published the first arbitrary and open to dispute. However, failure to agree on American-European Consensus Conference (AECC) crite- a definition will leave clinicians and researchers rudder- ria for ARDS and related syndromes in 1994. less. Without a unified definition of a disease, it is difficult The AECC definition had 4 key components. First, the to conduct epidemiologic studies, to assess the benefits and syndrome must present acutely. Second, there must be harms of potential therapies, and ultimately to care

Journal

JAMAAmerican Medical Association

Published: Jun 20, 2012

References