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The Accuracy of Diagnosis of Posterior Uveal Melanoma-Reply

The Accuracy of Diagnosis of Posterior Uveal Melanoma-Reply This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In reply Dr Margo is correct in concluding that findings from clinical trials with rigid selection criteria are not universally applicable to all patients and physicians but only to patients who meet the enrollment criteria established for those trials and to physicians with comparable diagnostic and treatment skills. It also is true that certain types of data from community-based outcomes studies have the potential of being more broadly applicable to the universe of patients with a particular condition. However, because of limitations inherent in the outcomes approach (eg, lack of uniform case definitions and lack of appropriate controls), results from carefully controlled clinical trials will continue to serve as guidelines to practice management for the foreseeable future.The COMS misdiagnosis rate, taken in the context of the results of the study by Dr Margo, illustrates the potential for minimizing misdiagnoses in clinical practice. The quality-control mechanisms in the COMS to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

The Accuracy of Diagnosis of Posterior Uveal Melanoma-Reply

Archives of Ophthalmology , Volume 115 (3) – Mar 1, 1997

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Publisher
American Medical Association
Copyright
Copyright © 1997 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1997.01100150434029
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In reply Dr Margo is correct in concluding that findings from clinical trials with rigid selection criteria are not universally applicable to all patients and physicians but only to patients who meet the enrollment criteria established for those trials and to physicians with comparable diagnostic and treatment skills. It also is true that certain types of data from community-based outcomes studies have the potential of being more broadly applicable to the universe of patients with a particular condition. However, because of limitations inherent in the outcomes approach (eg, lack of uniform case definitions and lack of appropriate controls), results from carefully controlled clinical trials will continue to serve as guidelines to practice management for the foreseeable future.The COMS misdiagnosis rate, taken in the context of the results of the study by Dr Margo, illustrates the potential for minimizing misdiagnoses in clinical practice. The quality-control mechanisms in the COMS to

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Mar 1, 1997

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