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Testicular Seminoma: A Review of 179 Patients Treated Over a 50-Year Period

Testicular Seminoma: A Review of 179 Patients Treated Over a 50-Year Period Abstract PRIMARY malignant tumors of the testes are relatively rare, contributing only 1% to 2% of all reported neoplasms in males. Morphologically, malignant testicular tumors are most simply divided according to origin into three categories, germinal, nongerminal, and metastatic. Seminoma, the most common germinal tumor, carries the least lethal prognosis. Recent reports of seminoma patients treated with radiotherapy indicate five-year survival figures of 80%,1 while even with metastasis treated with radiation, 38% five-year survival has been obtained.2 The variance of clinical behavior and prognosis of seminoma as compared to the other male germinal tumors prompted the review of 179 patients with seminoma admitted for evaluation and treatment at Roswell Park Memorial Institute, Buffalo, during the past 50 years. Since prolonged and detailed followup data were available, this review was undertaken in hopes of elucidating the natural history of the disease and studying its modification by a variety of therapeutic References 1. Lewis, L. C.: Testis Tumors: Report on 250 Cases, read before Southeastern Section of American Urological Association, Palm Beach, Fla, March 28, 1947. 2. Friedman, M., and Purkayashta, M.: Recurrent Seminoma of Testis , J Urol 84:360, 1960. 3. Cohn, A. E., and Tomskey, G. C.: Status of Hormonal Bio-Assay in Malignant Disease of Testicle: Review of Literature , Brit J Surg 33:173, 1945.Crossref 4. Melicow, M. M.: Classification of Tumors of Testes , J Urol 73:547, 1955. 5. Leadbetter, W. F.: Diagnosis and Treatment of Tumors of Testis , Amer J Surg 95:341, 1958.Crossref 6. Dixon, F. J., and Moore, R. A.: Testicular Tumors, Clinicopathological Study , Cancer 6:427, 1953.Crossref 7. Pollack, H. M.; Glauser, F.; and Colliuer, R.: Giant Tumor of Testis: Report of Unusually Large Seminoma , J Urol 87:145, 1962. 8. Sauer, H. R., and Burke, E. M.: Prognosis of Testicular Tumors , J Urol 63:69, 1949. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Testicular Seminoma: A Review of 179 Patients Treated Over a 50-Year Period

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Publisher
American Medical Association
Copyright
Copyright © 1965 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1965.01320080130027
Publisher site
See Article on Publisher Site

Abstract

Abstract PRIMARY malignant tumors of the testes are relatively rare, contributing only 1% to 2% of all reported neoplasms in males. Morphologically, malignant testicular tumors are most simply divided according to origin into three categories, germinal, nongerminal, and metastatic. Seminoma, the most common germinal tumor, carries the least lethal prognosis. Recent reports of seminoma patients treated with radiotherapy indicate five-year survival figures of 80%,1 while even with metastasis treated with radiation, 38% five-year survival has been obtained.2 The variance of clinical behavior and prognosis of seminoma as compared to the other male germinal tumors prompted the review of 179 patients with seminoma admitted for evaluation and treatment at Roswell Park Memorial Institute, Buffalo, during the past 50 years. Since prolonged and detailed followup data were available, this review was undertaken in hopes of elucidating the natural history of the disease and studying its modification by a variety of therapeutic References 1. Lewis, L. C.: Testis Tumors: Report on 250 Cases, read before Southeastern Section of American Urological Association, Palm Beach, Fla, March 28, 1947. 2. Friedman, M., and Purkayashta, M.: Recurrent Seminoma of Testis , J Urol 84:360, 1960. 3. Cohn, A. E., and Tomskey, G. C.: Status of Hormonal Bio-Assay in Malignant Disease of Testicle: Review of Literature , Brit J Surg 33:173, 1945.Crossref 4. Melicow, M. M.: Classification of Tumors of Testes , J Urol 73:547, 1955. 5. Leadbetter, W. F.: Diagnosis and Treatment of Tumors of Testis , Amer J Surg 95:341, 1958.Crossref 6. Dixon, F. J., and Moore, R. A.: Testicular Tumors, Clinicopathological Study , Cancer 6:427, 1953.Crossref 7. Pollack, H. M.; Glauser, F.; and Colliuer, R.: Giant Tumor of Testis: Report of Unusually Large Seminoma , J Urol 87:145, 1962. 8. Sauer, H. R., and Burke, E. M.: Prognosis of Testicular Tumors , J Urol 63:69, 1949.

Journal

Archives of SurgeryAmerican Medical Association

Published: Feb 1, 1965

References