Tamoxifen Flare
Abstract
To the Editor.—
We have read the article by Plotkin et al in The Journal (240:2644, 1979) regarding a flare from tamoxifen used in patients with breast cancer. We have also experienced this complication in greater numbers than earlier information suggested.
As Plotkin and associates point out, the increased, sometimes excruciating pain occurs within the first seven to ten days of use and often will lead to discontinuation either by the patient or by the physician.
Our first several...