Abstract • An acanthotic and papillomatous cutaneous lesion with a seborrheic verruca (keratosis)-like clinical appearance that, under light microscope examination, shows intermingling of sweat ductal and epidermal cells is described. Other lesions related to the distal end of the eccrine sweat duct have been recorded before, but these lesions, named syringoacanthoma herein, have not been described previously, to my knowledge. Twenty-one cases of syringoacanthoma, 12 benign and nine malignant, are reviewed and their relationship with similar lesions is discussed. (Arch Dermatol 1984;120:751-756) References 1. Mehregan AH, Hashimoto K, Rahbari H: Eccrine adenocarcinoma: A clinicopathologic study of 35 cases . Arch Dermatol 1983;119:104-114.Crossref 2. Evans HL, Su WPD, Smith JL, et al: Carcinoma arising in eccrine spiradenoma . Cancer 1979;43:1881-1884.Crossref 3. Harrist TJ, Aretz TH, Mihm MC Jr, et al: Malignant chondroid syringoma . Arch Dermatol 1981;117:719-724.Crossref 4. Mehregan AH, Rahbari H: Benign epithelial tumors of the skin: V. Benign eccrine gland tumors . Cutis 1979;23:573-577. 5. Johnson BL Jr, Helwig EB: Eccrine acrospiroma: A clinicopathologic study . Cancer 1969;23:641-657.Crossref 6. Winkelmann RK, McLeod WA: The dermal duct tumor . Arch Dermatol 1966;94:50-55.Crossref 7. Pinkus H, Rogin JR, Goldman P: Eccrine poroma: Tumors exhibiting features of the epidermal sweat duct unit . Arch Dermatol 1956;74:511-521.Crossref 8. Smith JLS, Coburn JG: Hidroacanthoma simplex: Assessment of selected group of intraepidermal basal cell epitheliomata and of their malignant homologues . Br J Dermatol 1956;68:400-418.Crossref 9. Rahbari H: Hidroacanthoma simplex: A review of 15 cases . Br J Dermatol 1983;109:219-225.Crossref 10. Mishima Y, Morioka S: Oncogenic differentiation of the intraepidermal eccrine sweat duct: Eccrine poroma, poroepithelioma and porocarcinoma . Dermatologica 1969;138:238-250.Crossref 11. Morales A, Hu F: Seborrheic verruca and intraepidermal basal cell epithelioma of Jadassohn . Arch Dermatol 1965;91:342-344.Crossref 12. Holubar K, Wolff K: Intraepidermal eccrine poroma: A histochemical and enzyme-histochemical study . Cancer 1969; 23:626-635.Crossref 13. Mehregan AH, Pinkus H: Intraepidermal epithelioma: A critical study . Cancer 1964;17:609-636.Crossref 14. Jadassohn J: Demonstration von selteneren Hautepitheliomen . Beitr Klin Chir 1926;136:345-358. 15. Pinkus H, Mehregan AH: Basal Cell Epithelioma: A Guide to Dermatohistopathology , ed 3. New York, Appleton-Century-Crofts, 1981, p 467. 16. Borst M: Meber die Mooglichkeit einer ausgedehnten intraepidermalen Verbreitung des Hautkrebses . Verh Dtsch Ges Pathol 1904;7:118-123.
Archives of Dermatology – American Medical Association
Published: Jun 1, 1984
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