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SYPHILIS: A Review of the Recent Literature

SYPHILIS: A Review of the Recent Literature Abstract SINCE the compilation of the 16th Annual Review of Syphilis,1 there has been ample affirmation of the theme that syphilis is still "rearing its ugly head" but syphilologists are rapidly disappearing, in this country at least. This is exemplified by the suspension (for economic reasons?) of the Journal of Venereal Disease Information; by the removal of syphilology from the great university departments of dermatology because of the realization that syphilis, like leprosy, is probably a public health department matter, and by Evan Thomas' fears for the future, in which he pictures the possible rise of the incidence of syphilis because of war or other disaster in the United States or Canada, where the training of competent syphilologists has been all but abandoned by the non-public-health facilities. The gradual drop in incidence of venereal disease in general, and syphilis in particular, during the period 1947-1951 has now been officially documented. References 1. Beerman, H.; Ford, W. T.; Nicholas, L., and Katzenstein, L.: Syphilis: A Review of the Recent Literature , A. M. A. Arch. Int. Med. 89:309-352 ( (Feb.) )Crossref 2. 464-519 (March) 1952. 3. Wile, U. J.: Cutaneous Medicine in the Medical Curriculum , A. M. A. Arch. Dermat. & Syph. 64:119-125 ( (Aug.) ) 1951. 4. Wortmann, F.: Syphilis: Juni 1950-Juni 1951 , Dermatologica 103:318-347, 1951. 5. Hermans, E. H.: Newer Concepts of Therapy in Syphilis , Acta dermat. venereol. 31:375-390, 1951. 6. Arnold, R. C.; Cutler, J. C.; Wright, R. D., and Levitan, S.: Studies in Penicillin Treatment of Syphilis , Pub. Health Rep. 67:78-89 ( (Jan.) ) 1952. 7. Fishbein, M.: The Decline of Syphilis, editorial , Postgrad. Med. 10:255-256 ( (Sept.) ) 1951. 8. Ingraham, N. R., Jr.: Newer Developments in Venereal Disease Control in the United States and Abroad , Tr. & Stud. Coll. Physicians Philadelphia 19:25-32 ( (April) ) 1951. 9. Bauer, T. J.: Editorial , J. Ven. Dis. Inform. 32:351-353 ( (Dec.) ) 1951. 10. Weiss, R. S., and Joseph, H. L.: Syphilis , New York, Williams & Wilkins Company, 1951. 11. Kendell, H. W.: Fever Therapy , Publication 80, American Lecture Series, American Lectures in Physical Medicine, edited by W. A. Selle, Springfield, Ill., Charles C Thomas, Publisher, 1951. 12. Welch, H., and Lewis, C. N.: Antibiotic Therapy , Washington, Arundel Press, Inc., 1951. 13. Cole, H. N.: Antiquity of Syphilis with Some Observations on Its Treatment Through the Ages , A. M. A. Arch. Dermat. & Syph. 64:12-22 ( (July) ) 1951. 14. Fitzwilliams, D. C. L.: Fracastorius and the Origin of Syphilis , M. World, London 74:659-661 ( (Aug. 10) ) 15. 690-693 (Aug. 17) 1951. 16. Schönfeld, W.: Franzosen-Ärtztinnen , Dermat. Wchnschr. 123:509-515, 1951 17. Brit. J. Ven. Dis. 28:31 ( (March) ) 1952. 18. Clarke, W.: Henry VIII and the French Pocks , J. Social Hyg. 37:306-321 ( (Oct.) ) 1951. 19. Davis, D. J.: The Medical History of the 4 Voyages of Columbus , Proc. Inst. Med. Chicago 18:363-365 ( (Oct. 15) ) 1951. 20. Gloyne, S. R.: John Hunter , Baltimore, Williams & Wilkins Company, 1950. 21. Willcox, R. R.: Views on the Treatment of Venereal Disease in the Early Nineteenth Century as Reflected in the Writings of Samuel Cooper , Brit. J. Ven. Dis. 27:179-182 ( (Dec.) ) 1951. 22. McCleary, J. E., and Farber, E. M.: Dermatological Writings of Sir Jonathan Hutchinson , A. M. A. Arch. Dermat. & Syph. 65:130-136 ( (Feb.) ) 1952. 23. McKusick, V. A.: The Clinical Observations of Jonathan Hutchinson , Am. J. Syph. 36:101-126 ( (March) ) 1952. 24. Hoffmann, E.: Über auffallend schnelle Wandlung des Krankheitsbildes der Syphilis und ihre Ursachen , Dermat. Wchnschr. 123:169-173, 1951. 25. Schönfeld, W.: Jarisch-Herxheimersche Reaktion und Leukoderme medizin-geschichtlich gesehen , Hautarzt 2:472-477 ( (Oct.) ) 1951. 26. Haanes, M.; DeLamater, E. D., and Saurino, V. R.: Studies on the Life Cycle of Spirochetes: IX. Studies in the Filterable Phase of Spirochetes , Am. J. Syph. 36:38-40 ( (Jan.) ) 1952. 27. Hampp, E. G.: Further Studies on the Significance of Spirochetal Granules , J. Bact. 62:347-349 ( (Sept.) ) 1951. 28. DeLamater, E. D.: A Study of the Life Cycle of Spirochetes and Other Micro-Organisms by Means of Phase Contrast and Routine Microscopy , Tr. New York Acad. Sc. 14:199-201 ( (March) ) 1952.Crossref 29. Poetschke, G., and Kaiser, B.: Der Nachweis von Treponema pallidum mit dem Phasenkontrastmikroskop , Hautarzt 2:408-410 ( (Sept.) ) 1951. 30. Morton, H. E.; Rake, G., and Rose, N. R.: Electron Microscope Studies of Treponemes: III. Flagella , Am. J. Syph. 35:503-516 ( (Nov.) ) 1951. 31. Angulo, J. J.; Watson, J. H. L.; Wedderburn, C.; Leon-Blanco, F., and Varela, G.: Electronmicrography of Treponemas from Cases of Yaws, Pinta, and the So-Called Cuban Form of Pinta , Am. J. Trop. Med. 31:458-478 ( (July) ) 1951. 32. Rice, F. A. H., and Nelson, R. A., Jr.: The Isolation from Beef Serum of a Survival Factor for Treponema Pallidum , J. Biol. Chem. 191:35-41 ( (July) ) 1951. 33. Rose, N. R., and Morton, H. E.: The Cultivation of Treponemes with the Preservation of Characteristic Morphology , Am. J. Syph. 36:1-16 ( (Jan.) ) 1952. 34. Rose, N. R., and Morton, H. E.: The Morphologic Variation of Treponema , Am. J. Syph. 36:17-37 ( (Jan.) ) 1952. 35. Levine, B. J.: Staining Treponema Pallidum and Other Treponemata , Pub. Health Rep. 67:253-257 ( (March) ) 1952.Crossref 36. Rosahn, P. D., and Freeman, M. L. H.: A Modified Fontana Technique for Staining Spirochetes in Smears , Am. J. Syph. 36:244-249 ( (May) ) 1952. 37. Rouquès, L.: Une technique simple pour la coloration des spirochetes , Presse méd. 59: 1441 ( (Nov. 3) ) 1951. 38. Coutts, W. E.; Silva-Inzuna, E., and Morales-Silva, G.: Unstained Slides for the Diagnosis of Certain Treponematoses , Pub. Health Rep. 67:442 ( (May) ) 1952.Crossref 39. Stokes, J. H.; Beerman, H., and Ingraham, N. R., Jr.: Modern Clinical Syphilology , Ed. 3, Philadelphia, W. B. Saunders Company, 1944. 40. Binder, E.: Über den Einfluss niedriger Temperaturen, insbesondere bei Eisschrankaufbewahrung von Transfusionsblut, auf die Syphilisspirochäte , Ärztl. Wchnschr. 6:901 ( (Sept. 21) ) 1951. 41. Menshoff, A. A.: Modifications of the Dark Field with a Black Circle for the Investigation of Spirochaeta in Vivo , Vestnik Venereol. 1:56 ( (Jan.-Feb.) ) 1951. 42. Vaisman, A.: Part Played by Route of Inoculation in Transmission of Syphilis to the Mouse , Ann. dermat. et syph. 10:651-656 ( (Nov.-Dec.) ) 1951. 43. Frazier, C. N.; Bensel, A., and Keuper, C. S.: Further Observations on the Duration of Spirochetemia in Rabbits with Asymptomatic Syphilis , Am. J. Syph. 36:167-173 ( (March) ) 1952. 44. Kolmer, J. A.: Penicillin in the Treatment of Experimental Syphilis of Rabbits: VII. Penicillin "S-R" and Procaine Penicillin G in Peanut Oil with Aluminum Monostearate, Alone and in Combination with Oxophenarsine Hydrochloride (Mapharsen®) or Bismuth Subsalicylate , A. M. A. Arch. Dermat. & Syph. 64:169-176 ( (Aug.) ) 1951. 45. Hollander, D. H.; Turner, T. B., and Nell, E. E.: The Effect of Long Continued Subcurative Doses of Penicillin During the Incubation Period of Experimental Syphilis , Bull. Johns Hopkins Hosp. 90:105-120 ( (Feb.) ) 1952. 46. Shteinlukht, L. A.: Effect of Small Doses of Penicillin on the Course of Syphilis in Rabbits , Vestnik Venereol. 2:18-19 ( (March-April) ) 1951. 47. Kolmer, J. A.: Terramycin Hydrochloride Alone and with Mapharsen and Bismuth in Treatment of Experimental Syphilis of Rabbits , Proc. Soc. Exper. Biol. & Med. 79:143-145 ( (Jan.) ) 1952. 48. Ovchinnikov, N. M., and Zelikova, R. L.: Effect of Penicillin on Spirochaeta Pallida in Vitro (Electron Microscope Investigations) , Vestnik Venereol. 1:18-20 ( (Jan.-Feb.) ) 1951. 49. Tauber, H.; McLeod, C.; Garson, W., and Magnuson, H. J.: Spirocheticidal Activity of Plasma and Serum Fractions , Proc. Soc. Exper. Biol. & Med. 78:110-112 ( (Oct.) ) 1951. 50. Tani, T., and Asano, O.: Studies on the Agglutination of Treponema Pallidum: II. On the Agglutination of Treponema Pallidum Treated with Antiformin in Human Serum and Cerebrospinal Fluid , Jap. M. J. 4:51-53 ( (Feb.) ) 1951. 51. McLeod, C. P., and Arnold, R. C.: A Study of Immunity in Experimental Syphilis as. Demonstrated by Contact Exposure Challenge , J. Ven. Dis. Inform. 32:279-283 ( (Oct.) ) 1951. 52. Magnuson, H. J., and Thompson, F. A., Jr.: Heterologous Strain Immunity in Experimental Syphilis , J. Immunol. 67:35-40 ( (July) ) 1951. 53. Magnuson, H. J., and Thompson, F. A., Jr.: The Effect of Repeated Cured Infections on the Development of Acquired Homologous Strain Immunity in Experimental Syphilis , Am. J. Syph. 36:237-243 ( (May) ) 1952. 54. Waring, G. W., and Fleming, W. L.: Further Attempts to Immunize Rabbits with Killed Treponema Pallidum , Am. J. Syph. 35:568-572 ( (Nov.) ) 1951. 55. Krech, U.: Experimentelle Untersuchungen über die Immunitätsverhältnisse bei Syphilis , Ztschr. Hyg. 133:122-126 ( (Aug. 23) ) 1951. 56. McLeod, C. P., and Magnuson, H. J.: A Study of Cross Immunity Between Syphilis and Yaws in Treated Rabbits , J. Ven. Dis. Inform. 32:305-309 ( (Nov.) ) 1951. 57. DeLamater, E. D.; Saurino, V. R., and Urbach, F.: Studies on the Immunology of Spirochetes: I. Effect of Cortisone on Experimental Spirochetosis , Am. J. Syph. 36:127-139 ( (March) ) 1952. 58. Higoumenakis, G.: Contribution ä l'étude de l'action immunisante de la peau dans la syphilis , Ann. dermat. et syph. 78:144-151 ( (March-April) ) 1951. 59. Seeberg, G.: Increase of Sensitivity to Organic Luetin on Repeated Testing , Acta dermat.venereol. 31:442-445, 1951. 60. Lavergne, G. H.: Intradermal Tests with Treponema Pallidum for the Diagnosis of Syphilis , Paris méd. (Supp. 3) 4:83 ( (May-June) ) 1951. 61. Hirsch, H.: Behandlung der seroresistenten Lues latens mit Organ-Luetin , Ztschr. Haut- u. Geschlechtskr. 11:59-64 ( (July 15) ) 1951. 62. Krag, P.: Die gegenwärtige Lage auf dem gebiet der Serodiagnostik der Syphilis , Wien. med. Wchnschr. 101:365-369 ( (May 19) ) 1951. 63. Rein, C. R.: Problemas en el serodiagnóstico de la sífilis , Bol. Ofic. san. panam. 31:105-117 ( (Aug.) ) 1951. 64. Editorial , Brit. J. Ven. Dis. 27:49-51 ( (June) ) 1951. 65. Touraine, A.: Syphilis et sérologie , Paris méd. 41:393-396 ( (Sept. 22-29) ) 1951. 66. Mason, M. A.: Trends in the Serodiagnosis of Syphilis , Canad. J. M. Technol. 13:153-158 ( (Dec.) ) 1951. 67. Puccinelli, V. A.: Recent Advances in the Serodiagnosis of Syphilis , Am. J. Syph. 35:340-349 ( (July) ) 1951. 68. Gabriel, H.: Über den augenblicklichen Stand der Luesserologie in der Vereinigten Staaten , Ztschr. Haut- u. Geschlechskr. 11:54-58 ( (July 15) ) 1951. 69. Citron, J.: A Positive Serology Reaction of Syphilis in Relation to Laws of Immigration , Hebrew M. J. 1:196-200, 1951. 70. Newer Antigens, Controls, and Types in Complement, in the Serology of Syphilis, and Associated Considerations , Indian M. Gaz. 86:359-364 ( (Aug.) ) 1951. 71. Stout, G. W., and Cutler, J. C.: Serology Problems (Syphilis) in Central America , J. Ven. Dis. Inform. 32:237-241 ( (Sept.) ) 1951. 72. Paul, J. R.; Riordan, J. T., and Kraft, L. M.: Serological Epidemiology: Antibody Patterns in North Alaskan Eskimos , J. Immunol. 66:695-713 ( (June) ) 1951. 73. Nørgaard, O.: La réaction de Wasermann sur le sang du cordon ombilical , Acta dermat.-venereol. 31:153-165, 1951. 74. Maxwell, R. W., and Scott, V.: The Provocative Serological Reaction in Late Syphilis: Its Relation to Technical Factors , Ann. Int. Med. 36:979-991 ( (April) ) 1952.Crossref 75. Heywood, C. P.: Interpretation of Serum Reactions in Late Syphilis , Brit. J. Ven. Dis. 28:3-12 ( (March) ) 1952. 76. Osler, A. G.; Strauss, J. H., and Mayer, M. M.: Diagnostic Complement Fixation: I. A Method , Am. J. Syph. 36:140-153 ( (March) ) 1952. 77. Osler, A. G.; Strauss, J. H., and Mayer, M. M.: Diagnostic Complement Fixation: II. Application to Serodiagnosis of Syphilis , Am. J. Syph. 36:154-162 ( (March) ) 1952. 78. Puccinelli, V. A.: La pluralità degli anticorpi nel siero del sifilitico e sua importanza nella prattica clinica, in Extract from the Transactions of the Thirty-Eighth Congress of the Italian Society of Dermatology and Sifilography, Catania and Taormina, Edizioni Minerva Medica Torino, 1951, Vol. 2, pp. 1-123. 79. Merklen, F. P., and Berthaux, P.: Étude sur la nature des réagines responsables des réaction sérologiques de la syphilis , Bull. Soc. méd. hôp. Paris 68:129-135 ( (Jan. 25) and Feb. 1) 1952 80. Emploi systématique des réactions quantitatives de floculation dans un service de dermatosyphilographie parisien , Merklen Bull. Soc. méd. hôp. Paris 68:135-142 ( (Jan. 25) and Feb. 1) 1952 81. Localisation des réagines dans les fractions euglobuliniques des serums syphilitiques , Bull. Soc. franç. dermat. et syph. 58:294-296 ( (May-June) ) 1951. 82. Pangborn, M. C.; Maltaner, F.; Tompkins, V. N.; Beecher, T.; Thompson, W. R., and Flynn, M. R.: Cardiolipin Antigens: Preparation and Chemical and Serological Control , Monograph Series, No. 6, World Health Organization, Geneva, 1951 83. Cardiolipin Antigens , Bull. World Health Organ. 4:151-200, 1951. 84. Cardiolipin Antigens , Chron. World Health Organ. 5:265-267 ( (Oct.) ) 1951. 85. Joulia, P., and Pautrizel, R.: Avantage des antigènes à base de cardiolipide dans les tests sérologiques de la syphilis , Bull. Soc. franç. dermat. et syph. 58:243-245 ( (May-June) ) 1951. 86. Joulia, P., and Pautrizel, R.: Utilisation des antigènes à base de cardiolipide dans la surveillance sérologique des malades traites par la penicillin seule: Intérèt des tests quantitatifs , Bull. Soc. franç. dermat. et syph. 58:242-243 ( (May-June) ) 1951. 87. Flynn, M. R.; Tompkins, V., and Beecher, T.: Egg Lecithin in Cardiolipin Antigens , Am. J. Syph. 36:272-277 ( (May) ) 1952. 88. Brede, H. D.: Cardiolipin-Syphilistest mit Kurzinaktivierung und Wärme-Kälte-Bindung , Ztschr. Hyg. 133:235-240, 1951.Crossref 89. Kail, G.: Vergleichsuntersuchungen zwischen einer cardiolipinverwendeten WaR. und den bisherigen Wiener Routinemethoden , Ztschr. Haut-u. Geschlechtskr. 11:273-280 ( (Oct. 1) ) 1951. 90. Piantanida, M.: Statistic̆ka analiza serodijagnostika na lues , Acta med. iugoslav. 5:250-264, 1951. 91. Giordano, A. S.; Shively, J. A., and Bahler, J. W.: Employment of Commercially Prepared Cardiolipin Microflocculation Antigen in the Kolmer Complement-Fixation Test , Am. J. Clin. Path. 22:285-290 ( (March) ) 1952. 92. Lundbäck, H., and Allander, A. L.: Studies on the Wassermann Reaction: Some Factors Responsible for Variation in Activity of the Cardiolipin-Lecithin-Cholesterol Antigen in Aqueous Solution , Acta path. et microbiol. scandinav. 29:287-296, 1951.Crossref 93. Klose, R.: Ein Beitrag zur Frage der Verwendung des Cardiolipins als Antigen für die Lues-Diagnose , Ärztl. Wchnschr. 6:589-591 ( (June 22) ) 1951 94. Price, I. N. O., and Wilkinson, A. E.: Comparative Serum Testing with Cardiolipin and Crude Heart Extract Wassermann Antigens , Brit. J. Ven. Dis. 28:16-20 ( (March) ) 1952 95. Parallel Testing with Crude Heart Extract Wassermann Antigens , Price Brit. J. Ven. Dis. 27:191-193 ( (Dec.) ) 1951. 96. Rappaport, F., and Eichhorn, F.: A Rapid Test for the Serodiagnosis of Syphilis with Cardiolipin Antigens , Acta med. orient. 10:200-204 ( (Aug.-Sept.) ) 1951. 97. Vogelsang, T. M., and Haaland, R.: The VDRL Tube Flocculation Test: A Macroflocculation Test for Syphilis Using Cardiolipin-Lecithin-Cholesterol Antigen , Brit. J. Ven. Dis. 27:52-58 ( (June) ) 1951. 98. Mazzini, L. Y.: Mazzini Cardiolipin Microflocculation Test for Syphilis , J. Immunol. 66:261-275 ( (Feb.) ) 1951. 99. Rein, C. R.; Kelcec, L. C., and Rosenfield, T. M.: The Role of Sitolipin in Serologic Tests for Syphilis , Am. J. Syph. 35:573-577 ( (Nov.) ) 1951. 100. Archambault, J.: Quantitative Serologic Tests for the Diagnosis of Syphilis and Control of Treatment , Canad. J. Pub. Health 42:323-328 ( (Aug.) ) 1951. 101. Zia, S. H.; Chao, C. J., and Chiang, Y. T.: A Comparative Quantitative Study of Slide Kahn, VDRL, and Half-Volume Kolmer Complement Fixation Test , Chinese M. J. 69:19-23 ( (Jan.-Feb.) ) 1951. 102. Harris, A., and Bossak, H. N.: A Rapid Method for Performing Quantitative Tests for Syphilis in Large-Scale Testing Programs , J. Ven. Dis. Inform. 32:203-206 ( (Aug.) ) 1951. 103. Harris, A.; Harding, V. L., and Bossak, H. N.: Serum Standards for Serologic Tests for Syphilis , J. Ven. Dis. Inform. 32:310-318 ( (Nov.) ) 1951. 104. Cannefax, B. S.: A Demonstration of the Stability of Dehydrated Serum and Suggestions for Its Use , J. Ven. Dis. Inform. 32:319-327 ( (Nov.) ) 1951. 105. Redmond, A.; Nicol, C. S., and Shooter, R. A.: A Note on the Patterns of Quantitative Serological Tests in Late Syphilis , Brit. J. Ven. Dis. 28:13-15 ( (March) ) 1952. 106. Machala, W. E., and Hassler, F. R.: The Effect of an Additional Four Minutes' Rotation on Reactions to the VDRL Slide Flocculation Test , J. Ven. Dis. Inform. 32:192-195 ( (July) ) 1951. 107. Cutter, J. C., and Harris, A.: Studies on the Comparative Behavior of Various Serologic Tests for Syphilis: I. A Report on Serologic Findings Among Patients with Primary Syphilis at Beginning of Therapy , J. Ven. Dis. Inform. 32:328-335 ( (Nov.) ) 1951. 108. Chediak, A.: El diagnostico de la sifilis practicado en una gota de sangre desecada y desfibrinada , Arch. med. inf. 1:3-14, 1952. 109. Olansky, S.; Harris, A.; Vinson, H.; Bossak, H. N., and Portnoy, J.: A Comparison of Serologic Tests , Pub. Health Rep. 67:563-572 ( (June) ) 1952.Crossref 110. Harris, A.; Olansky, S., and Vinson, H.: The Chediak Test: A Preliminary Report , Pub. Health Rep. 67:572-576 ( (June) ) 1952.Crossref 111. Cannefax, G. R.; Beyer, H. R., and Johnwick, E. B.: A Micromodification of the VDRL Slide Test , Pub. Health Rep. 67:576-581 ( (June) ) 1952.Crossref 112. Harris, A.; Olansky, S., and Miller, H.: A Statistical Evaluation of the FPM Test , Pub. Health Rep. 67:581-585 ( (June) ) 1952.Crossref 113. Freeble, C. R., Jr., and Orsburn, B.: Use of the FPM Test in a Control Program , Pub. Health Rep. 67:585-588 ( (June) ) 1952.Crossref 114. Singh, B., and Sharma, M. D.: Parallel Serum Testing with the VDRL Slide Test, the Meinicke Slide Test, and the Price Precipitation Reaction , Brit. J. Ven. Dis. 27:190 ( (Dec.) ) 1951. 115. Hecht, H.: Verification Test for Pseudosyphilitic Reactions , Ohio M. J. 48:213-218 ( (March) ) 1952. 116. Kahn, R. L.: Present Status of Universal Reaction in Health and Disease , Univ. Michigan M. Bull. 17:217-239 ( (July) ) 1951. 117. Kahn, R. L.: Serology with Lipid Antigen , Baltimore, Williams & Wilkins Company, 1950 118. An Introduction to the Universal Serologic Reaction in Health and Disease , New York, Commonwealth Fund, Division of Publications, 1951. 119. Stout, G.; Guzman, M., and Scrimshaw, N. S.: Presumptive False Positive Serologic Reactions for Syphilis in Central America: I. Incidence and Distribution , Am. J. Syph. 36:41-48 ( (Jan.) ) 1952. 120. Stout, G.; Guzman, M., and Scrimshaw, N. S.: Presumptive False Positive Serologic Reactions for Syphilis in Central America: II. Relation to Serum Ascorbic Acid, Riboflavin, Alkaline Phosphatase, Carotene, and Vitamins A and E in Blood Serum , Am. J. Syph. 36:49-54 ( (Jan.) ) 1952. 121. Stout, G.; Méndez, J.; Guzmán, M., and Scrimshaw, N. S.: Presumptive False Positive Serologic Reactions for Syphilis in Central America: III. Relation to Serum Protein, Albumin, and Globulin , Am. J. Syph. 36:55-59 ( (Jan.) ) 1952. 122. Stout, G.; Aguirre, F., and Scrimshaw, N. S.: Presumptive False Positive Serologic Reactions for Syphilis in Central America: IV. Relation to Positive Reactions for Cephalin Cholesterol (Hanger) Flocculation Test , Am. J. Syph. 36:60-63 ( (Jan.) ) 1952. 123. Zellman, H. E.: The Incidence of Positive Serologic Tests for Syphilis in the Collagen Diseases , Am. J. Syph. 36:163-166 ( (March) ) 1952. 124. Brede, H. D.: Entlarvung "falscher positiver" Luesreaktionen , Arch. Hyg. 134:229-236, 1951. 125. Aron, H. C. S.; Parkhurst, G. E.; Rodriquez, J., and Harris, W. W.: Further Observations on Biologic False Positive Serologic Tests in Young Children , Am. J. Syph. 36:278-283 ( (May) ) 1952. 126. Levrè, V.: Sulle siero-reazioni aspecifiche nei casi di affezioni delle vie respiratorie , Arch. ital. dermat. sif. 24:109-115, 1951. 127. Wiedemann, G.: Über die Beeinflussung der serologischen Luesreaktionen durch den Scharlach , Ztschr. ärztl. Fortbild. 45:409-413 ( (Aug. 15) ) 1951. 128. Caselitz, F. H.: Zur Frage unspezifischer Luesreaktionen bei internen Erkrankungen (Klinische Beispiele) , Med. Welt. 20:837-840 ( (June 30) ) 1951. 129. Lennette, E. H.; Clark, W. H., and Jensen, F. W.: Q Fever Studies: XII. Certain Observations on the Relationships Between Serologic Tests for Brucellosis, Syphilis, and Q Fever , Am. J. Pub. Health 42:12-19 ( (Jan.) ) 1952. 130. Rottmann, A., and Teichmann, J.: Zur Frage der Spezifität der serologischen Luesreaktionen unter Berücksichtigung vergleichender Untersuchungen an Tierseren , Wien. med. Wchnschr. 101:522-525 ( (July 14) ) 1951. 131. Kail, F., and Marcus, G. H.: Unspezifisch positive serologische Luesreaktion bei Antitetanusgeimpften , Wien. med. Wchnschr. 101:913-916 ( (Dec. 1) ) 1951. 132. Geier, F.: Positive Lues-Seroreaktionen durch Alkoholgenuss? Ärztl. Wchnschr. 6:891-892 ( (Sept. 21) ) 1951. 133. Ferreira-Marques, J.: Die negativmachende Wirkung des Vitamins B1 auf die Wassermannsche u. Kahnsche Reaktion , Wien. med. Wchnschr. 101:593-594 ( (Aug. 11) ) 1951. 134. Copley, A. L.: New Needle Device for Repeated Blood Withdrawals , J. A. M. A. 147: 1139 ( (Nov. 17) ) 1951.Crossref 135. The Treponemal Immobilization Test, Annotation , Brit. J. Ven. Dis. 27:97-98 ( (June) ) 1951. 136. Levaditi, C.: Les immobilisines antitréponémiques: Méthode de Nelson et Mayer , Presse méd. 59:1361-1363 ( (Oct. 20) ) 1951. 137. Vaisman, A., and Hamelin, A.: Le test d'immobilisation du "treponema pallidum": Réaction de Nelson , Presse méd. 59:1418-1420 ( (Oct. 27) ) 1951. 138. Demanche, R.: Epreuve d'immobilisation des treponemes de Nelson et Mayer , Paris méd. 41:396-400 ( (Sept. 22) ) 1951. 139. Nelson, R. A., Jr., and Diesendruck, J. A.: Studies on Treponemal Immobilizing Antibodies in Syphilis: I. Techniques of Measurement and Factors Influencing Immobilization , J. Immunol. 66:667-685 ( (June) ) 1951. 140. McLeod, C. P., and Magnuson, H. J.: Development of Treponemal Immobilizing Antibodies in Mice Following Injection of Killed Treponema Pallidum (Nichols Strain) , J. Ven. Dis. Inform. 32:274-279 ( (Oct.) ) 1951. 141. Magnuson, H. J.; Thompson, F. A., Jr., and McLeod, C. P.: Relationship Between Treponemal Immobilizing Antibodies and Acquired Immunity in Experimental Syphilis , J. Immunol. 67:41-48 ( (July) ) 1951. 142. Dripps, R. D., and Vandam, L. D.: Hazards of Lumbar Puncture , J. A. M. A. 147: 1118-1121 ( (Nov. 17) ) 1951.Crossref 143. Kogoj, F.: The "Critical Moment" in Syphilis Treatment and Times of the Examination of the Spinal Fluid , Acta dermat.-venereol. 32:86-92, 1952. 144. Sciarra, D., and Carter, S.: Lumbar Puncture Headache , J. A. M. A. 148:841-842 ( (March 8) ) 1952.Crossref 145. Hart, J. R., and Whitacre, R. J.: Pencil-Point Needle in Prevention of Postspinal Headache , J. A. M. A. 147:657-658 ( (Oct. 13) ) 1951.Crossref 146. Putkonen, T., and Kajanne, H.: Contamination of Cerebrospinal Spinal Fluid by Blood in Examinations for Neurosyphilis , Ann. med. intern. Fenniae 40:28-36, 1951. 147. Davis, M. R.; Cannefax, G. R., and Johnwick, E. B.: Cerebrospinal Fluid: Comparative Study of Specimens Taken from Cisterna Magna and Lumbar Subarachnoid Space , J. Ven. Dis. Inform. 32:284-288 ( (Oct.) ) 1951. 148. Ford, W. T.; Stokes, J. H.; Beerman, H., and Gentzkow, C. J.: Comparison of the Results of Spinal Fluid Examination by 2 Separate Laboratories on Duplicate Specimens of Spinal Fluid from Four Hundred Patients with Syphilis , Am. J. Syph. 35:553-558 ( (Nov.) ) 1951. 149. Gross, B. A.: Quantitative Spinal Fluid Protein Determination , Am. J. Syph. 35:350-355 ( (July) ) 1951. 150. Daughaday, W. H.; Lowry, O. H.; Rosebrough, N. J., and Fields, W. S.: Determination of Cerebrospinal Fluid Protein with Folin Phenol Reagent , J. Lab. & Clin. Med. 39:663-665 ( (April) ) 1952. 151. Ulbricht, H.: Phasenkontrastmikroskopische Liquorzelluntersuchungen: I. Die Rundzellen des frühsyphilitischen Liquors , Arch. Dermat. u. Syph. 193:56-62 ( (Aug. 14) ) 1951. 152. Cannefax, G. R., and Tow, C. W.: Temperature Effect on the Colloidal Mastic Test , Pub. Health Rep. 67:490-491 ( (May) ) 1952.Crossref 153. Koenigstein, R. P., and Chang, S. T.: Colloidal Gold Reaction in the Spinal Fluid in Leprosy , Internat. J. Leprosy 19:323-326 ( (July-Sept.) ) 1951. 154. Streitmann, B.: Syphilis und Tuberkulose , Klin. med. 6:474-482 ( (Oct.) ) 1951. 155. Gartmann, H.: Zur Frage der rückläufigen Transfusionssyphilis , Deutsche gesundh. 6:1278-1283 ( (Nov. 8) ) 1951. 156. Syphilitic Blood and Transfusions, Queries and Minor Notes , J. A. M. A. 146:1088 ( (July 14) ) 1951. 157. Gaskell, K. H.: Radiology in Syphilis , Brit. J. Ven. Dis. 27:59-74 ( (June) ) 1951. 158. Rogerson, H. L.: Venereophobia in the Male , Brit. J. Ven. Dis. 27:158-159 ( (Sept.) ) 1951. 159. Sonck, C. E.: Infectiousness in Syphilis , Acta dermat.-venereol. 31:599-604, 1951. 160. Putkonen, T.: A Primary Chancre of the Vagina: Report of a Case , Acta dermat.venereol. 31:395-397, 1951. 161. Torchi, M.: Rilievi clinico-statistici sui sifilomi extragenitali , Arch. ital. dermat. sif. 24:137-142, 1951. 162. Dexter, H. L. T., and Clarke, G. E.: Vesicular Lesions in Secondary Syphilis , A. M. A. Arch. Dermat. & Syph. 65:615-616 ( (May) ) 1952. 163. Vilanova, X., and de Moragas, J. M.: Sifilis y traumatismo: A proposito de un caso de sifilide palmar psoriasiforme unilateral surgida en un camarero , Actas dermo-sif. 42:702-705 ( (April) ) 1951. 164. Lubeck, G., and Epstein, E.: Complications of Tattooing , California Med. 76:83-85 ( (Feb.) ) 1952. 165. Dexter, H. T., and Rockwell, E. M.: Simultaneous Condylomata Acuminata and Condylomata Lata: Report of a Case , A. M. A. Arch. Dermat. & Syph. 64:205-206 ( (Aug.) ) 1951. 166. Troitskaya, A. D.: Modification of Blood Vessels in Early Syphilis , Vestnik Venerol. 1:34-35 ( (Jan.-Feb.) ) 1951. 167. Merrell, M.: Estimates of Relapse and Reinfection Rates in Early Syphilis Treated with Penicillin , Am. J. Syph. 35:532-543 ( (Nov.) ) 1951. 168. Noguer-More, S.: Algunas consideraciones acerca des las reinfecciones lueticas: El "ping-pong-lues," Actas dermo-sif. 42:695-701 ( (April) ) 1951. 169. Laird, S. M.: Neuro-Recurrence After Penicillin Therapy of Secondary Syphilis , Urol. & Cutan. Rev. 55:475-477 ( (Aug.) ) 1951. 170. Harmos, O., and Myers, M. E.: Gummatous Syphilitic Splenomegaly: Report of a Case , Am. J. Clin. Path. 21:737-742 ( (Aug.) ) 1951. 171. Hollingsworth, G.: Gumma of Lung , Brit. J. Radiol. 24:467-468 ( (Aug.) ) 1951. 172. Fancher, P. S.: Syphilis of the Stomach , Ann. Int. Med. 35:240-248 ( (July) ) 1951.Crossref 173. Carney, R. G., and Radcliffe, C. E.: Multiple Miliary Osteomas of the Skin , A. M. A. Arch. Dermat. & Syph. 64:483-486 ( (Oct.) ) 1951. 174. Langer, E., and Sperling, E.: Die Häufigkeit der Spätlues , Ztschr. Haut- u. Geschlechtskr. 11:47-53 ( (July 15) ) 1951. 175. Shapiro, E., and Weiner, H.: The Diagnosis of Tertiary Syphilis of the Liver: 25 Years After McCrae , Am. J. M. Sc. 222:494-499 ( (Nov.) ) 1951. 176. Hunt, C. L.: Cardiovascular Syphilis , Canad. M. A. J. 66:324-329 ( (April) ) 1952. 177. Zeman, F. D., and Storch, S.: Syphilitic Heart Disease in the Aged , Ann. Int. Med. 36:1423-1436 ( (June) ) 1952. 178. Dotter, C. T., and Steinberg, I.: Angiocardiography , Circulation 4:123-138 ( (July) ) 1951. 179. Woods, F. M., and Kenny, L. J.: Congenital Aortic Aneurysm: Report of a Case , J. A. M. A. 148:1216-1218 ( (April 5) ) 1952. 180. Rich, C., and Webster, B.: The Natural History of Uncomplicated Syphilitic Aortitis , Am. Heart J. 43:321-332 ( (March) ) 1952. 181. Carroll, D.: Non-Traumatic Aortic Valve Rupture , Bull. Johns Hopkins Hosp. 89:309-325 ( (Oct.) ) 1951. 182. Daniel, R. A.: Syphilitic Aneurysm of the Subclavian Artery , Ann. Surg. 134:251-258 ( (Aug.) ) 1951. 183. Silver, G. B., and Kahn, J. W.: Popliteal Aneurysm Due to Syphilis: Report of a Case , Ann. Int. Med. 36:888-896 ( (March) ) 1952. 184. Farquharson, C. D.: Aneurysm of Abdominal Aorta , Bull. Acad. Med., Toronto 24:176-178 ( (Aug.) ) 1951. 185. McCloskey, J. F., and Chu, P. T.: Lesions of the Vasa Vasorum and Dissecting Aneurysms of the Aorta: Analysis of Incidence, Etiological Aspects, Pathogenesis, and Pathological Changes , A. M. A. Arch. Path. 52:132-144 ( (Aug.) ) 1951. 186. Domzalski, C. A., Jr.: Diagnosis of Dissecting Aneurysm of the Aorta , A. M. A. Arch. Int. Med. 88:770-782 ( (Dec.) ) 1951. 187. Logue, R. B., and Sikes, C.: A New Sign in Dissecting Aneurysm of Aorta Pulsation of a Sternoclavicular Joint , J. A. M. A. 148:1209-1212 ( (April 5) ) 1952. 188. Fein, I.; Proctor, D., and Moore, J. E.: The Laryngeal Manifestations of Tabes Dorsalis , Am. J. Syph. 36:201-230 ( (May) ) 1952. 189. Willcox, R. R.: Some Observations on Neurosyphilis in the African Negro , J. Ven. Dis. Inform. 32:229-236 ( (Sept.) ) 1951 190. Syphilitic Mental Disease in the African Negro , J. Roy. Army M. Corps 97:97-110 ( (Aug.) ) 1951. 191. Souder, C., and Lawrence R.: Syphilis in Negro Patients , Delaware M. J. 23:232-233 ( (Aug.) ) 1951. 192. Koteen, H., and Darnley, J. D.: A Provocative Test for Tabes Dorsalis: Initiation of Characteristic Pains by Artificial Fever , Am. J. Syph. 36:231-236 ( (May) ) 1952. 193. Johansson, A.: On the Use of Schultze's 10 Words Test in Some Organic Cerebral Diseases , Acta psychiat. et neurol. , (Supp. 60) , pp. 181-202, 1951. 194. Nedo Zec: Neuropsychiatric Affections and Endemic Syphilis in Bosnia and Herzegovina , Acta med. iugoslav. 5:176-197, 1951. 195. Freeble, C. R., Jr., and Donohue, J. F.: Syphilis and Gonorrhea as Causes of Blindness: A Study of Persons Declared Legally Blind in Ohio , J. A. M. A. 146:1500-1506 ( (Aug. 18) ) 1951.Crossref 196. Klauder, J. V.: Blindness Due to Syphilis , J. Ven. Dis. Inform. 32:183-192 ( (July) ) 1951. 197. Oksala, A.: Studies on Interstitial Keratitis Associated with Congenital Syphilis Ocurring in Finland, Thesis, Helsinki, Kauppakirjapaino O. Y., 1951 198. Acta ophth. , 1952, (Supp. 38) , pp. 1-109. 199. Klauder, J. V.; Gross, B. A., and Hanno, H. A.: Endocrine Studies of Patients with Syphilitic Interstitial Keratitis , Am. J. Syph. 35:416-432 ( (Sept.) ) 1951. 200. Robinson, R. C. V.: Syphilitic Interstitial Keratitis After 5 Years of Seronegativity: A Case Report , Am. J. Syph. 36:92-94 ( (Jan.) ) 1952. 201. Borsche, A.: Diagnostisch atypische Fälle konnataler Lues , Deutsche med. Wchnschr. 76:1008-1010 ( (Aug.) ) 1951.Crossref 202. Ledoux, P.: Hérédo-syphilis pulmonaire , J. méd. Lyon 32:735-737 ( (Aug. 5) ) 1951. 203. Kirsch, J., and Ledourneuf, G.: Lésions précoces de la syphilis osseuse congénitale , Semaine méd. 27:730-731 ( (Oct. 10) ) 1951. 204. Kessel, I.: Congenital Syphilis: Short Case Notes with Radiological Illustrations , South African M. J. 26:1-4 ( (Jan. 5) ) 1952. 205. Dunlop, E. M. C.: A Case for Diagnosis with a Note on Infantile Cortical Hyperostosis (Caffey's Syndrome) , Brit. J. Ven. Dis. 27:194-199 ( (Dec.) ) 1951. 206. Vilanova, X., and de Dulanto, F.: Diagnostico de algunos casos de sifilis congenita asintomatica mediante la demonstracion radiologica de los incisivos de Hutchinson, antes de la segunda denticion , Actas dermo-sif. 42:682-685 ( (April) ) 1951. 207. Thompson, R. G., and Berry, C. Z.: Symmetrical Serous Synovitis , U. S. Armed Forces M. J. 2:1723-1727 ( (Nov.) ) 1951. 208. FitzGerald, J. L., Jr.; Ferris, G. N., and Toshach, C. E.: The Influence of Maternal and Obstetrical Factors on Fetal Survival , Am. J. M. Sc. 222:40-45 ( (July) ) 1951.Crossref 209. Mayer, M.: De la place occupée par la syphilis congénitale dans les avortements répétés et la mort habituelle du fætus , Semaine hôp. Paris 27:1285-1291 ( (April 22) ) 1951. 210. James, T.: Congenital Syphilis in One of Twins , Brit. J. Dermat. 63:389-398 ( (Nov.) ) 1951.Crossref 211. Raskin, R. A.: Congenital Syphilis in One of Apparently Identical Twins , Am. J. Syph. 35:334-339 ( (July) ) 1951. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Internal Medicine American Medical Association

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References (205)

Publisher
American Medical Association
Copyright
Copyright © 1953 American Medical Association. All Rights Reserved.
ISSN
0888-2479
DOI
10.1001/archinte.1953.00240160079008
Publisher site
See Article on Publisher Site

Abstract

Abstract SINCE the compilation of the 16th Annual Review of Syphilis,1 there has been ample affirmation of the theme that syphilis is still "rearing its ugly head" but syphilologists are rapidly disappearing, in this country at least. This is exemplified by the suspension (for economic reasons?) of the Journal of Venereal Disease Information; by the removal of syphilology from the great university departments of dermatology because of the realization that syphilis, like leprosy, is probably a public health department matter, and by Evan Thomas' fears for the future, in which he pictures the possible rise of the incidence of syphilis because of war or other disaster in the United States or Canada, where the training of competent syphilologists has been all but abandoned by the non-public-health facilities. The gradual drop in incidence of venereal disease in general, and syphilis in particular, during the period 1947-1951 has now been officially documented. References 1. 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L.: Further Attempts to Immunize Rabbits with Killed Treponema Pallidum , Am. J. Syph. 35:568-572 ( (Nov.) ) 1951. 55. Krech, U.: Experimentelle Untersuchungen über die Immunitätsverhältnisse bei Syphilis , Ztschr. Hyg. 133:122-126 ( (Aug. 23) ) 1951. 56. McLeod, C. P., and Magnuson, H. J.: A Study of Cross Immunity Between Syphilis and Yaws in Treated Rabbits , J. Ven. Dis. Inform. 32:305-309 ( (Nov.) ) 1951. 57. DeLamater, E. D.; Saurino, V. R., and Urbach, F.: Studies on the Immunology of Spirochetes: I. Effect of Cortisone on Experimental Spirochetosis , Am. J. Syph. 36:127-139 ( (March) ) 1952. 58. Higoumenakis, G.: Contribution ä l'étude de l'action immunisante de la peau dans la syphilis , Ann. dermat. et syph. 78:144-151 ( (March-April) ) 1951. 59. Seeberg, G.: Increase of Sensitivity to Organic Luetin on Repeated Testing , Acta dermat.venereol. 31:442-445, 1951. 60. Lavergne, G. H.: Intradermal Tests with Treponema Pallidum for the Diagnosis of Syphilis , Paris méd. 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Journal

A.M.A. Archives of Internal MedicineAmerican Medical Association

Published: Apr 1, 1953

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