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SYNDROME OF ANEMIA, GLOSSITIS AND DYSPHAGIA: REPORT OF EIGHT CASES, WITH SPECIAL REFERENCE TO OBSERVATIONS AT AUTOPSY IN ONE INSTANCE

SYNDROME OF ANEMIA, GLOSSITIS AND DYSPHAGIA: REPORT OF EIGHT CASES, WITH SPECIAL REFERENCE TO... Abstract The association of dysphagia, superficial glossitis and anemia has been noted sufficiently frequently during the past few years to have become regarded as a clinical entity, and has often been referred to as the "Plummer-Vinson syndrome." Since none of the many hypotheses concerning the nature of this condition appears to have been based on histopathologic data, it was thought that a report of the observations at autopsy in one instance might prove of value. In addition, a review of the literature and the clinical findings in eight cases of this syndrome are presented. The syndrome was first pointed out independently by Brown Kelly1 and by D. R. Paterson2 at the summer congress of the Laryngological Section of the Royal Society of Medicine in London, May 2, 1919, with papers entitled, respectively, "Spasm at the Entrance of the Oesophagus" and "A Clinical Type of Dysphagia." The condition, as described References 1. Kelly, A. B.: J. Laryng. & Otol. 34:285, 1919. 2. Paterson, D. R.: J. Laryng. & Otol. 34:289, 1919. 3. Vinson, P. P.: Minnesota Med. 5:107, 1922. 4. Plummer, cited by Vinson.3 5. Moersch, H. J., and Conner, H. M.: Hysterical Dysphagia , Arch. Otolaryng. 4:112 ( (Aug.) ) 1926. 6. Hurst, A. F.: Guy's Hosp. Rep. 76:426, 1926. 7. Ryle, J. A.: Guy's Hosp. Rep. 77:33, 1927. 8. Jones, A. M., and Owen, R. D.: Brit. M. J. 1:256, 1928. 9. Cameron, M.: J. Laryng. & Otol. 44:168, 1929. 10. Evans, G.: Practitioner 124:317, 1930. 11. Witts, L. J.: Guy's Hosp. Rep. 81:193, 1931. 12. Paterson, R. D.: Proc. Roy. Soc. Med. (Sect. Laryng.) 24:1203, 1931 13. J. Laryng. & Otol. 46:532, 1931. 14. Carr, F. H., and Price, E. A.: Biochem. J. 20:497, 1926. 15. Moore, T.: Biochem. J. 23:1267, 1929. 16. Hurst, A. F.: Brit. M. J. 1:375, 1928. 17. Rake, G. W.: Guy's Hosp. Rep. 76:145, 1926 18. Rake Guy's Hosp. Rep. 77:141, 1927. 19. Cameron, M.: J. Laryng. & Otol. 43:219, 1928. 20. Suzman, M. M.: Unpublished data (paper read before the Newcastle-upon-Tyne Pathological Club, Feb. 21, 1929). 21. Cameron, M.: Brit. M. J. 1:521, 1928. 22. Hill, W.: Brit. M. J. 1:467, 1928. 23. Moersch and Conner.5 24. Hurst.6 25. Cameron.9 26. Witts.11 27. Davies, D. T.: Lancet 2:385, 1931.Crossref 28. Johnson, R. S.: Proc. Roy. Soc. Med. (Sect. Laryng.) 24:1206, 1931. 29. Davies.19e Case 5 of present series. 30. Paterson.12 Davies.19e 31. Mills, E. S.: Canad. M. A. J. 22:175, 1930. 32. Minot, G. R., and Health, C. W.: Am. J. M. Sc. 183:110, 1932.Crossref 33. Kaznelson, P.; Reimann, F., and Weiner, W.: Klin. Wchnschr. 8:1071, 1929.Crossref 34. Watkins, C. H.: A Classification of Chronic Idiopathic Secondary Anemia , J. A. M. A. 93:1365 ( (Nov. 2) ) 1929.Crossref 35. Altschuller, G.: Acta med. Scandinav. 70:119, 1929.Crossref 36. Davies.19e 37. Witts, L. J.: Guy's Hosp. Rep. 80:253, 1930. 38. Davies, D. T.: Quart. J. Med. 24:447, 1931.Crossref 39. Davies (footnotes 19e 40. 27c). 41. Mettier, S. R., and Minot, G. R.: Am. J. M. Sc. 181:25, 1931.Crossref 42. Castle, W. B.: Am. J. M. Sc. 178:748, 1929.Crossref 43. Castle, W. B., and Townsend, W. C.: Am. J. M. Sc. 178:164, 1929.Crossref 44. Castle, W. B.; Townsend, W. C., and Heath, C. W.: Am. J. M. Sc. 180:305, 1930.Crossref 45. Castle, W. B.; Heath, C. W., and Strauss, M. B.: Am. J. M. Sc. 182:741, 1931.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

SYNDROME OF ANEMIA, GLOSSITIS AND DYSPHAGIA: REPORT OF EIGHT CASES, WITH SPECIAL REFERENCE TO OBSERVATIONS AT AUTOPSY IN ONE INSTANCE

Archives of Internal Medicine , Volume 51 (1) – Jan 1, 1933

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Publisher
American Medical Association
Copyright
Copyright © 1933 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1933.00150200004001
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Abstract

Abstract The association of dysphagia, superficial glossitis and anemia has been noted sufficiently frequently during the past few years to have become regarded as a clinical entity, and has often been referred to as the "Plummer-Vinson syndrome." Since none of the many hypotheses concerning the nature of this condition appears to have been based on histopathologic data, it was thought that a report of the observations at autopsy in one instance might prove of value. In addition, a review of the literature and the clinical findings in eight cases of this syndrome are presented. The syndrome was first pointed out independently by Brown Kelly1 and by D. R. Paterson2 at the summer congress of the Laryngological Section of the Royal Society of Medicine in London, May 2, 1919, with papers entitled, respectively, "Spasm at the Entrance of the Oesophagus" and "A Clinical Type of Dysphagia." The condition, as described References 1. Kelly, A. B.: J. Laryng. & Otol. 34:285, 1919. 2. Paterson, D. R.: J. Laryng. & Otol. 34:289, 1919. 3. Vinson, P. P.: Minnesota Med. 5:107, 1922. 4. Plummer, cited by Vinson.3 5. Moersch, H. J., and Conner, H. M.: Hysterical Dysphagia , Arch. Otolaryng. 4:112 ( (Aug.) ) 1926. 6. Hurst, A. F.: Guy's Hosp. Rep. 76:426, 1926. 7. Ryle, J. A.: Guy's Hosp. Rep. 77:33, 1927. 8. Jones, A. M., and Owen, R. D.: Brit. M. J. 1:256, 1928. 9. Cameron, M.: J. Laryng. & Otol. 44:168, 1929. 10. Evans, G.: Practitioner 124:317, 1930. 11. Witts, L. J.: Guy's Hosp. Rep. 81:193, 1931. 12. Paterson, R. D.: Proc. Roy. Soc. Med. (Sect. Laryng.) 24:1203, 1931 13. J. Laryng. & Otol. 46:532, 1931. 14. Carr, F. H., and Price, E. A.: Biochem. J. 20:497, 1926. 15. Moore, T.: Biochem. J. 23:1267, 1929. 16. Hurst, A. F.: Brit. M. J. 1:375, 1928. 17. Rake, G. W.: Guy's Hosp. Rep. 76:145, 1926 18. Rake Guy's Hosp. Rep. 77:141, 1927. 19. Cameron, M.: J. Laryng. & Otol. 43:219, 1928. 20. Suzman, M. M.: Unpublished data (paper read before the Newcastle-upon-Tyne Pathological Club, Feb. 21, 1929). 21. Cameron, M.: Brit. M. J. 1:521, 1928. 22. Hill, W.: Brit. M. J. 1:467, 1928. 23. Moersch and Conner.5 24. Hurst.6 25. Cameron.9 26. Witts.11 27. Davies, D. T.: Lancet 2:385, 1931.Crossref 28. Johnson, R. S.: Proc. Roy. Soc. Med. (Sect. Laryng.) 24:1206, 1931. 29. Davies.19e Case 5 of present series. 30. Paterson.12 Davies.19e 31. Mills, E. S.: Canad. M. A. J. 22:175, 1930. 32. Minot, G. R., and Health, C. W.: Am. J. M. Sc. 183:110, 1932.Crossref 33. Kaznelson, P.; Reimann, F., and Weiner, W.: Klin. Wchnschr. 8:1071, 1929.Crossref 34. Watkins, C. H.: A Classification of Chronic Idiopathic Secondary Anemia , J. A. M. A. 93:1365 ( (Nov. 2) ) 1929.Crossref 35. Altschuller, G.: Acta med. Scandinav. 70:119, 1929.Crossref 36. Davies.19e 37. Witts, L. J.: Guy's Hosp. Rep. 80:253, 1930. 38. Davies, D. T.: Quart. J. Med. 24:447, 1931.Crossref 39. Davies (footnotes 19e 40. 27c). 41. Mettier, S. R., and Minot, G. R.: Am. J. M. Sc. 181:25, 1931.Crossref 42. Castle, W. B.: Am. J. M. Sc. 178:748, 1929.Crossref 43. Castle, W. B., and Townsend, W. C.: Am. J. M. Sc. 178:164, 1929.Crossref 44. Castle, W. B.; Townsend, W. C., and Heath, C. W.: Am. J. M. Sc. 180:305, 1930.Crossref 45. Castle, W. B.; Heath, C. W., and Strauss, M. B.: Am. J. M. Sc. 182:741, 1931.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Jan 1, 1933

References