Abstract Recent observation of a patient with symptomatic psychosis due to chronic posthemorrhagic anemia led to an investigation of the psychiatric aspects of secondary anemia. It provoked also a consideration of the differences, if any, between the psychoses encountered with pernicious anemia and the symptomatic psychosis experienced by our patient. Considerable attention has been devoted in recent years to psychoses associated with pernicious anemia.1 It is not thought necessary here to review the extensive literature on the subject, as several recent articles,1h,j have done this adequately. Except for two recent authors,1l,m all expressed the belief that the psychoses associated with pernicious anemia are causally related to the physical disease. Preu and Geiger1k attempted to clarify the nosologic position of these psychoses. They discussed the diagnostic criteria of a symptomatic psychosis and expressed the belief that the symptomatic psychoses arising in association with pernicious anemia have been insufficiently References 1. Pickett, W.: Mental Symptoms Associated with Pernicious Anemia , Am. J. M. Sc. 127:1032 ( (June) ) 1904.Crossref 2. Landon, F. W.: Nervous and Mental Manifestations of Pre-Pernicious Anemia , J. A. M. A. 45:1635 ( (Nov. 25) ) 1905.Crossref 3. Camp, C. D.: Pernicious Anemia Causing Spinal Cord Changes and a Mental State Resembling Paresis , M. Rec. 81:156 ( (Jan. 27) ) 1912. 4. Barrett, A. M.: Mental Disorders and Cerebral Lesions Associated with Pernicious Anemia , Am. J. Insan. 69:1063, 1913. 5. Lurie, L. A.: Pernicious Anemia with Mental Symptoms: Observations on the Varying Extent and Probable Duration of Central Nervous System Lesions in Four Necropsied Cases , Arch. Neurol. & Psychiat. 2:67 ( (July) ) 1919. 6. Jones, B. L., and Raphael, T.: Differential Diagnostic Difficulties in Pernicious Anemia with Associated Mental Disorder , Arch. Neurol. & Psychiat. 4:55 ( (July) ) 1920. 7. Woltman, H. W.: The Mental Changes Associated with Pernicious Anemia , Am. J. Psychiat. 3:435 ( (Jan.) ) 1924. 8. Warburg, E. J., and Jørgensen, S.: Psychoses and Neurastheniae Associated with Achylia Gastrica and Megalocytosis, and the Relation Between This Syndrome and Pernicious Anemia: I. Psychoses , Acta med. Scandinav. 69:537, 1928 9. II. Neurastheniae: Remarks on the Diagnostic Value of Color and Volume Indices , Warburg Acta med. Scandinav. 70:193, 1929. 10. Richardson, W.: Pernicious Anemia: Results of Treatment with Liver or Its Derivatives in Sixty-Seven Cases , New England J. Med. 200: 540 ( (March 14) ) 1929. 11. Bowman, K. M.: Psychoses with Pernicious Anemia , Am. J. Psychiat. 92:371 ( (Sept.) ) 1935. 12. Preu, P. W., and Geiger, A. J.: Symptomatic Psychoses in Pernicious Anemia , Ann. Int. Med. 9:766 ( (Dec.) ) 1935. 13. Hackfield, A. W.: Studies of the Etiological Relationship Between the Somatic and Psychotic Disturbances in Pernicious Anemia: A Critical Review , J. Nerv. & Ment. Dis. 76:31 ( (July) ) 1932. 14. Osgood, C. W.: Mental Changes Associated with Pernicious Anemia , J. A. M. A. 104:2155 ( (June 15) ) 1935. 15. Phillips, N. R.: Mental Disorders Associated with Pernicious Anemia , J. Ment. Sc. 77:549 ( (July) ) 1931. 16. Kahn, E.: Psychoses Complicating Other Diseases , Yale J. Biol. & Med. 7:215 ( (Jan.) ) 1935. 17. Bulloch, W., and Fildes, P.: Hemophilia, Treasury of Human Inheritance , Eugenics Laboratory Memoirs, no. 12, London, University of London, 1911. 18. Lord, J. P.: Hemophilia with Volkmann Syndrome: Report of Case , J. A. M. A. 87:406 ( (Aug. 7) ) 1926. 19. Seddons, H. J.: Hemophilia as a Cause of Lesions in the Nervous System , Brain , 53:306 ( (Oct.) ) 1930. 20. Günther, H.: Ueber Lähmungen bei Hämophilie , Monatschr. f. Psychiat. u. Neurol. 91:33 ( (April) ) 1935. 21. Hadden, S. B.: Neurological Symptoms in Post Hemorrhagic Secondary Anemia , Ann. Int. Med. 9:1572 ( (May) ) 1936.
Archives of Neurology & Psychiatry – American Medical Association
Published: Jun 1, 1938