Abstract WITH REPORTS of possible cures or prolonged remission of periarteritis nodosa with cortisone or corticotropin therapy, the early diagnosis of the disease becomes of greater significance. Either there is an increase in the frequency of the disease, or the increased awareness of the disease is resulting in more frequent diagnoses. Although the collagen diseases remain poorly understood, some progress is being made as the clinically benign forms of the disease are being separated from the severer forms.2 This progress may be enhanced by additional case reports of clinical and pathological findings. The surgeon is interested in this disease from several standpoints. The gastrointestinal tract is involved by this disease in 50 to 56% of the cases.* Hematemesis or melena occur in 18% of the cases. It should, therefore, be considered in the differential diagnosis of other surgical diseases of the abdomen. It is frequently the surgeon who is initially References 1. References 1 and 4. 2. Arkin, A.: Clinical and Pathological Study of Periarteritis Nodosa: Report of 5 Cases , Am. J. Path. 6:401, 1930. 3. Churg, J., and Strauss, L.: Allergic Granulomatosis, Allergic Angiitis, and Periarteritis Nodosa , Am. J. Path. 27:277 ( (March-April) ) 1951. 4. Ehrenreich, T., and Olmstead, E. V.: Malignant Hypertension Following Administration of Cortisone in Periarteritis Nodosa , A. M. A. Arch. Path. 52:145 ( (Aug.) ) 1951. 5. Hall, J. W.; Sun, S.-C., and Mackler, W.: Arteritis of Appendix , Arch. Path. 50:240 ( (Aug.) ) 1950. 6. Kussmaul, A., and Maier, R.: Über eine bisher nicht beschriebene eigentümliche Arterienerkrankung (Periarteritis Nodosa), die mit Morbus Brightii und rapid fortschreitender allgemeiner Muskellähmung einhergeht , Deutsches Arch. klin. Med. 1:484, 1866. 7. Logue, R. B., and Mullins, F.: Polyarteritis Nodosa: Report of 11 Cases with Review of Recent Literature , Ann. Int. Med. 24:11 ( (Jan.) ) 1946.Crossref 8. Plaut, A.: Asymptomatic Focal Arteritis of the Appendix: Eighty-Eight Cases , Am. J. Path. 27:247 ( (March-April) ) 1951. 9. Symmers, St. C., and Litchfield, J. A.: Healing Polyarteritis Nodosa: Observations on Three Cases After ACTH and on One Case After Sympathectomy , Lancet 2:1193 ( (Dec.) ) 1952.Crossref
A.M.A. Archives Surgery – American Medical Association
Published: Oct 1, 1954
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