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Surgery in Patients With Coagulopathies Using Desmopressin Acetate

Surgery in Patients With Coagulopathies Using Desmopressin Acetate This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract At the 92nd annual meeting of the American Academy of Otolaryngology–Head and Neck Surgery in Washington, DC, Dr Egbert DeVries, MD, and coworkers, Pittsburgh, Pa, described their experience over the last 2 years in performing surgery in patients with significant coagulopathies that had been corrected preoperatively by employing 1-D-amino (8-D-arginine)-vasopressin (desmopressin acetate [DDAVP, USV Laboratories, Tarrytown, NY]). This drug has been shown to normalize factor VIII coagulant, factor VIII–related antigen, and von Willebrand factor (ristocetin cofactor), thus correcting prolonged bleeding times. Prior to the widespread availability of desmopressin acetate, these patients would have been administered blood products with the inherent risks of transfusion reaction or possible transmission of blood-born disease, especially hepatitis and the acquired immunodeficiency syndrome. Dr DeVries related a particularly interesting case. He and his colleagues were asked to examine a 76-year-old woman with renal failure complicated by acute respiratory failure. Coagulation studies in this patient showed abnormal http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology - Head & Neck Surgery American Medical Association

Surgery in Patients With Coagulopathies Using Desmopressin Acetate

Surgery in Patients With Coagulopathies Using Desmopressin Acetate

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract At the 92nd annual meeting of the American Academy of Otolaryngology–Head and Neck Surgery in Washington, DC, Dr Egbert DeVries, MD, and coworkers, Pittsburgh, Pa, described their experience over the last 2 years in performing surgery in patients with significant coagulopathies that had been corrected preoperatively by employing 1-D-amino...
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Publisher
American Medical Association
Copyright
Copyright © 1989 American Medical Association. All Rights Reserved.
ISSN
0886-4470
eISSN
1538-361X
DOI
10.1001/archotol.1989.01860300017006
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract At the 92nd annual meeting of the American Academy of Otolaryngology–Head and Neck Surgery in Washington, DC, Dr Egbert DeVries, MD, and coworkers, Pittsburgh, Pa, described their experience over the last 2 years in performing surgery in patients with significant coagulopathies that had been corrected preoperatively by employing 1-D-amino (8-D-arginine)-vasopressin (desmopressin acetate [DDAVP, USV Laboratories, Tarrytown, NY]). This drug has been shown to normalize factor VIII coagulant, factor VIII–related antigen, and von Willebrand factor (ristocetin cofactor), thus correcting prolonged bleeding times. Prior to the widespread availability of desmopressin acetate, these patients would have been administered blood products with the inherent risks of transfusion reaction or possible transmission of blood-born disease, especially hepatitis and the acquired immunodeficiency syndrome. Dr DeVries related a particularly interesting case. He and his colleagues were asked to examine a 76-year-old woman with renal failure complicated by acute respiratory failure. Coagulation studies in this patient showed abnormal

Journal

Archives of Otolaryngology - Head & Neck SurgeryAmerican Medical Association

Published: Jun 1, 1989

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