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Superheated Nebulized Saline and Gastric Lavage: To Obtain Bacterial Cultures in Primary Pulmonary Tuberculosis in Children

Superheated Nebulized Saline and Gastric Lavage: To Obtain Bacterial Cultures in Primary... Abstract IN YOUNG children infected with tuberculosis, positive identification of the organism by culture is very important not only to make the definitive diagnosis but also to document the drug sensitivity of the infecting tubercle bacillus. These data allow continued measurement of the prevalence of drug resistant bacteria in a community. It has been conventional clinical practice to do early morning gastric aspiration in children on three successive days to obtain specimens for bacteriologic studies. Lincoln and Sewell1 state in their excellent review book that... cultures obtained during the early phase of primary tuberculosis and before any antimicrobial therapy is given are most likely to be positive. Under the best conditions, bacilli have been recovered in 50% to 90% of all children with roentgenographic evidence of pulmonary primary tuberculosis, but in the average hospital only one quarter to one third of gastric lavages of children suspected of active tuberculosis yield References 1. Lincoln, E.M., and Sewell, E.M.: Tuberculosis in Children, Gastric Lavage , New York: McGraw-Hill Book Co., Inc., 1963, p 49. 2. Schwartz, I., and Small, M.J.: Preliminary Studies in the Use of Superheated Saline Nebulization in the Bacteriologic Diagnosis of Pulmonary Tuberculosis , Amer Rev Resp Dis 84:279-280 ( (Aug) ) 1961. 3. Steiner, M., and Cosio, A.: Primary Tuberculosis in Children , New Eng J Med 274:755-759 ( (April 7) ) 1966.Crossref 4. Elliott, R.C., and Reichel, J.: The Efficacy of Sputum Specimens Obtained by Nebulization Versus Gastric Aspirates in the Bacteriologic Diagnosis of Pulmonary Tuberculosis , Amer Rev Resp Dis 88:223-227 ( (Aug) ) 1963. 5. Lillehei, J.P.: Sputum Induction With Aerosol Inhalations for Diagnosis of Tuberculosis , Amer Rev Resp Dis 84:276-278 ( (Aug) ) 1961. 6. Yue, W.Y., and Cohen, S.S.: Sputum Induction by Newer Inhalation Methods in Patients With Pulmonary Tuberculosis , Dis Chest 51:614-620 ( (June) ) 1967.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Superheated Nebulized Saline and Gastric Lavage: To Obtain Bacterial Cultures in Primary Pulmonary Tuberculosis in Children

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Publisher
American Medical Association
Copyright
Copyright © 1969 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1969.02100030200014
Publisher site
See Article on Publisher Site

Abstract

Abstract IN YOUNG children infected with tuberculosis, positive identification of the organism by culture is very important not only to make the definitive diagnosis but also to document the drug sensitivity of the infecting tubercle bacillus. These data allow continued measurement of the prevalence of drug resistant bacteria in a community. It has been conventional clinical practice to do early morning gastric aspiration in children on three successive days to obtain specimens for bacteriologic studies. Lincoln and Sewell1 state in their excellent review book that... cultures obtained during the early phase of primary tuberculosis and before any antimicrobial therapy is given are most likely to be positive. Under the best conditions, bacilli have been recovered in 50% to 90% of all children with roentgenographic evidence of pulmonary primary tuberculosis, but in the average hospital only one quarter to one third of gastric lavages of children suspected of active tuberculosis yield References 1. Lincoln, E.M., and Sewell, E.M.: Tuberculosis in Children, Gastric Lavage , New York: McGraw-Hill Book Co., Inc., 1963, p 49. 2. Schwartz, I., and Small, M.J.: Preliminary Studies in the Use of Superheated Saline Nebulization in the Bacteriologic Diagnosis of Pulmonary Tuberculosis , Amer Rev Resp Dis 84:279-280 ( (Aug) ) 1961. 3. Steiner, M., and Cosio, A.: Primary Tuberculosis in Children , New Eng J Med 274:755-759 ( (April 7) ) 1966.Crossref 4. Elliott, R.C., and Reichel, J.: The Efficacy of Sputum Specimens Obtained by Nebulization Versus Gastric Aspirates in the Bacteriologic Diagnosis of Pulmonary Tuberculosis , Amer Rev Resp Dis 88:223-227 ( (Aug) ) 1963. 5. Lillehei, J.P.: Sputum Induction With Aerosol Inhalations for Diagnosis of Tuberculosis , Amer Rev Resp Dis 84:276-278 ( (Aug) ) 1961. 6. Yue, W.Y., and Cohen, S.S.: Sputum Induction by Newer Inhalation Methods in Patients With Pulmonary Tuberculosis , Dis Chest 51:614-620 ( (June) ) 1967.Crossref

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Feb 1, 1969

References